ID A0A1Q8IPE3_9BURK Unreviewed; 757 AA.
AC A0A1Q8IPE3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Propionate catabolism operon regulatory protein PrpR {ECO:0000313|EMBL:OLL28555.1};
GN ORFNames=BTH42_27575 {ECO:0000313|EMBL:OLL28555.1};
OS Burkholderia sp. SRS-W-2-2016.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=1926878 {ECO:0000313|EMBL:OLL28555.1, ECO:0000313|Proteomes:UP000186182};
RN [1] {ECO:0000313|Proteomes:UP000186182}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRS-W-2-2016 {ECO:0000313|Proteomes:UP000186182};
RA Chauhan A.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLL28555.1}.
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DR EMBL; MSDV01000063; OLL28555.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q8IPE3; -.
DR STRING; 1926878.BTH42_27575; -.
DR Proteomes; UP000186182; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR012704; Sig_transdc_resp-reg_PrpR.
DR InterPro; IPR010524; Sig_transdc_resp-reg_PrpR_N.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR NCBIfam; TIGR02329; propionate_PrpR; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR32071:SF77; TRANSCRIPTIONAL REGULATORY PROTEIN GLRR; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF06506; PrpR_N; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF159800; PrpR receptor domain-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000186182};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 194..238
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 415..648
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT REGION 239..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 696..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 757 AA; 79348 MW; 716C8934C8FC2E9C CRC64;
MPGVALVSIS RLQSLCETVA PRYAGQARFF PVREGYAAAV AALQAYVDAG SVDVVLAAGS
NGAYLRDHLS VPVVMVKVNG FDVLNAITRA TTSRPGARIG LVLYETIAHE LDELGPWLNV
GLTQRAYRSP DDVRLAVEQL AAAGCGVIIG PGMACDLAQQ AGIDSVFLYS LGAVEEAFER
SVELARVSRQ QEARRRRLNT IVAHLRDGVA AFDHAGQLEA VNPAMLELLG VAPDATRGDG
LASGPARGDG LASGPARGDG LASGPPRGDG LASGPARGDG LVSGMASDDL APGATRGRGL
APNAARGDGL VSDIARGANH VHAQVARALA PLLREALAAT APGDGRIERI ERIERIEQIG
GRALSVNCVP IVEQGARAGF VVTAQDALVA QRIERSLRTS QRPKHLVARH RLDDLIGASP
ALARVRRLAH AGAAHDATVL LTGESGTGKE LVAQGIHNAS RRRGNPFVAF NCAALPEGLI
ESELFGHEEG AFTGARRGGK PGLFEIAHTG TIFLDEIGEM PAALQSRLLR VLQEREVMKL
GAGRATPIDV RVIAATHRDL LELVEQGAFR ADLYFRLNLL QIKLPPLRER RADIAPLARH
LLARSASQYG LPAASFERVL AFLEPLFAQY AWPGNVRELE NLLARAAIYV GDSGHEPAID
SSDDAAGNSP VTALPDWQAV FPEFGRLGPA MAALAGPAGA AGPAGPPPEA AAGSSLPRST
PTREDALRAL EQSGGNRAAA SRALGIGRTT LWRLLKG
//
