ID A0A1Q8IWT9_9BURK Unreviewed; 990 AA.
AC A0A1Q8IWT9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=BTH42_13220 {ECO:0000313|EMBL:OLL31165.1};
OS Burkholderia sp. SRS-W-2-2016.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=1926878 {ECO:0000313|EMBL:OLL31165.1, ECO:0000313|Proteomes:UP000186182};
RN [1] {ECO:0000313|Proteomes:UP000186182}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRS-W-2-2016 {ECO:0000313|Proteomes:UP000186182};
RA Chauhan A.;
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLL31165.1}.
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DR EMBL; MSDV01000026; OLL31165.1; -; Genomic_DNA.
DR RefSeq; WP_075299930.1; NZ_MSDV01000026.1.
DR AlphaFoldDB; A0A1Q8IWT9; -.
DR STRING; 1926878.BTH42_13220; -.
DR Proteomes; UP000186182; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd00156; REC; 1.
DR CDD; cd18161; REC_hyHK_blue-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43065:SF49; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF08448; PAS_4; 2.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00072; Response_reg; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 2.
DR SMART; SM00448; REC; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 2.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000186182}.
FT DOMAIN 31..88
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 90..142
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 229..287
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 394..449
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 487..710
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 730..846
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 876..987
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 780
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 925
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 990 AA; 108469 MW; 024BEF2FA17C69E7 CRC64;
MQVNDQSVAG ATLSGNGHFE LMIERVRDYA IYLLTPAGLV KSWNEGAERI KGYSAAEIIG
QHFSLFYTAE DRATDLPARA LDISVREGKF ESEGWRVRKD GSRFRAHVVL DALFDDAGHH
IGYAKITRDI TAEYEARRSA EQQNQLALDA RNREYQELLR LFEQAPGFVC FFRGPEHVYQ
LQNSAHHRLA GFRDILGKPV RQALPELVGQ GFFELLDEVY RSGKAFVGRA LPLRVDPLAA
EKNEEGEVRF IDFVYQPIVD DHGAVVGIFS QGNDVTEQVL AQQALEHKQE ELERLVLERT
AALEKTSQTL QLARELHLDK AHLLQLFEQA PGFICVLKTG QHIFELANSA YRSLVGERDL
VGRRVQDALP EVTEQGFIEL LDRVFRTGQP FVGTSVPVKI QPRDSAKLET RFLDFVYQPI
SGPDGEVIGI FVQGHDVTAQ KLAQDELQRY QTSLEALVQE RTRELEHTQT ALQRSQKLEA
IGKLTGGIAH DFNNILQVIG GNLQLLQSHL IDDCPALNRV NTATSAVERG AKLSSQLLAF
ARRQPLQPVA TNLAPVITGM DDMLRRALGE SVIIETVLAG GLWNVLVDPN QLENVVLNLA
INARDAMPDG GKLSIELGNS MLDDDYVASD DDLLPGQYVL LAISDTGVGM TREVMERACD
PFFTTKPEGT GTGLGLSMAY GFVKQSGGHF KIYSEPGHGS TIKIYLPRSH EAVVQTAPPV
TLAVVGGSET ILVVEDDLAV QATVVEMLRE LGYHVLKADN AESALGILRS GLSIDLLFTD
VVMPGTMRSP DLARRAKALL PDIEVLFTSG YTQNAIVHGG RLDAGVHLLT KPYRREQLAR
KIRHLLSNGQ AAALARAEPP AAETEAAVPS PCRALHVLVV EDQPDLREMA VELIRMMGHH
AQAAASGEEA IEVFARSGFD VLLTDVGLPG IDGVELSRQL VTVKPGLHVI FASGYGHAIG
DGADRLGTVL PKPYTFAGLE TLLASFSGED
//
