ID A0A1Q8RMP2_9PEZI Unreviewed; 1086 AA.
AC A0A1Q8RMP2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Regulator of nonsense transcripts 1-like protein {ECO:0000313|EMBL:OLN85582.1};
GN ORFNames=CCHL11_05845 {ECO:0000313|EMBL:OLN85582.1};
OS Colletotrichum chlorophyti.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum.
OX NCBI_TaxID=708187 {ECO:0000313|EMBL:OLN85582.1, ECO:0000313|Proteomes:UP000186583};
RN [1] {ECO:0000313|EMBL:OLN85582.1, ECO:0000313|Proteomes:UP000186583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NTL11 {ECO:0000313|EMBL:OLN85582.1,
RC ECO:0000313|Proteomes:UP000186583};
RA Gan P., Narusaka M., Tsushima A., Narusaka Y., Takano Y., Shirasu K.;
RT "Draft Genome Assembly of Colletotrichum chlorophyti a pathogen of
RT herbaceous plants.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00000600};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:13066;
CC Evidence={ECO:0000256|ARBA:ARBA00000600};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the DNA2/NAM7 helicase family.
CC {ECO:0000256|ARBA:ARBA00007913}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLN85582.1}.
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DR EMBL; MPGH01000162; OLN85582.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q8RMP2; -.
DR STRING; 708187.A0A1Q8RMP2; -.
DR OrthoDB; 170190at2759; -.
DR Proteomes; UP000186583; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR CDD; cd21407; 1B_UPF1-like; 1.
DR CDD; cd18039; DEXXQc_UPF1; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR CDD; cd21400; ZBD_UPF1-like; 1.
DR Gene3D; 2.40.30.230; -; 1.
DR Gene3D; 6.10.140.1240; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR040812; UPF1_1B_dom.
DR InterPro; IPR018999; UPF1_CH/ZBD.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF364; REGULATOR OF NONSENSE TRANSCRIPTS 1; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF18141; UPF1_1B_dom; 1.
DR Pfam; PF09416; UPF1_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51997; UPF1_CH_RICH; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022806};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU01341}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000186583};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU01341};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU01341}.
FT DOMAIN 90..247
FT /note="Upf1"
FT /evidence="ECO:0000259|PROSITE:PS51997"
FT REGION 43..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 98..130
FT /note="C3H"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01341"
FT REGION 112..140
FT /note="CC/SHH/C"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01341"
FT REGION 158..188
FT /note="C4"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01341"
FT REGION 1064..1086
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1086 AA; 119517 MW; 337BAE20871441F7 CRC64;
MEGAFSHVGN HLLSNSAAAI KAGADDFTGI GIDPDESLLY GKFGGRGGRR RADDDDNQTE
LYEDDDNDSL TSVPVGAMKD LNLGRPQEED RELPPHACAY CGIHSPSSVV KCLGCNKWFC
SARGNATSSH IVNHLVRARH KEVQLHPEST LGDTVLECYN CGTKNVFLLG FIPAKSDTVV
VLLCRQPCAA NTSSKDMSWD TSRWQPLIEE RAFLTWLVAT PSDAEQLRAR HLTPPMIAKL
EEMWKENSTA TVADLEKAAS IDDDPHPVLL KYDDPYHYQN IFGPLVKMES DYDKKLKEAQ
SEDGLTVRWD YGLNNKHLVS FELHKIESGD VKLAVGDEMR LRYKGELRPA WEGVGYVIKI
PNNQSDEVTL ELRKAGNEKT VPTECTHNFS ADYVWKATSY DRMQYAMKTF AVDDMSVSGY
IFHKLLGHEV AVAPMKTSMP KKFSVPGLPD LNTSQIAAIK AVLQNPLSLI QGPPGTGKTV
TSATIIYHLC KMNNGQVLVC APSNVAVDQL CERIHRTGLK VVRLTAKSRE DVESSVSFLA
LHEQVRMNDS NGELVKLAQL KSELGELSSQ DEKKFKQLTK AAERDILHNA DVVCCTCVGA
GDPRLSKMKF RNVLIDESTQ SAEPECMIPL VLGCKQVVLV GDHKQLGPVI MNKKAAKAGL
NQSLFERLVN LRLVPIRLNI QYRMHPCLSE FPSNMFYDGS LQNGVTVKER LRKDVDFPWP
VGDMPMMFWS NLGNEEISAS GTSYLNRTEA SNVEKVVTRF FKAGVKPLDI GVITPYEGQR
SYIVSTMQNT GTFKKESYKE VEVASVDAFQ GREKDFIVLS CVRSNDNQGI GFLSDPRRLN
VALTRAKYGL VIIGNPKVLS KHELWHHLLV HFKDRKCLVE GPLTNLQTSL LQFGKPRTAY
RQKMSQPPQF NATGFPNGNR FNGAGSTRDF DSGSMMSYIP DDVSSIHSSL GGAGLNTTYP
PIFSSFTPEQ WPGLPGVPGA GRSGNKRGRA TESIAGESVA NSEYTDASAS VIGAKGVGQG
GVSLGAGLQD AIHGMRPASY SHSDRLKQYV ESGGRMGHGN GFGRRYDDDE KSVSTAFHSQ
IGGGFD
//
