ID A0A1Q8RPI7_9PEZI Unreviewed; 11300 AA.
AC A0A1Q8RPI7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=CCHL11_04129 {ECO:0000313|EMBL:OLN86255.1};
OS Colletotrichum chlorophyti.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum.
OX NCBI_TaxID=708187 {ECO:0000313|EMBL:OLN86255.1, ECO:0000313|Proteomes:UP000186583};
RN [1] {ECO:0000313|EMBL:OLN86255.1, ECO:0000313|Proteomes:UP000186583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NTL11 {ECO:0000313|EMBL:OLN86255.1,
RC ECO:0000313|Proteomes:UP000186583};
RA Gan P., Narusaka M., Tsushima A., Narusaka Y., Takano Y., Shirasu K.;
RT "Draft Genome Assembly of Colletotrichum chlorophyti a pathogen of
RT herbaceous plants.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NRP synthetase family.
CC {ECO:0000256|ARBA:ARBA00029454}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLN86255.1}.
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DR EMBL; MPGH01000132; OLN86255.1; -; Genomic_DNA.
DR STRING; 708187.A0A1Q8RPI7; -.
DR OrthoDB; 2301216at2759; -.
DR Proteomes; UP000186583; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 8.
DR CDD; cd05918; A_NRPS_SidN3_like; 1.
DR CDD; cd02440; AdoMet_MTases; 2.
DR CDD; cd19531; LCL_NRPS-like; 8.
DR Gene3D; 3.30.300.30; -; 12.
DR Gene3D; 3.40.50.980; -; 16.
DR Gene3D; 1.10.1200.10; ACP-like; 8.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 9.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 10.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 3.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR013216; Methyltransf_11.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 8.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 9.
DR Pfam; PF13193; AMP-binding_C; 3.
DR Pfam; PF00668; Condensation; 9.
DR Pfam; PF08241; Methyltransf_11; 1.
DR Pfam; PF00550; PP-binding; 9.
DR SMART; SM00823; PKS_PP; 9.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 9.
DR SUPFAM; SSF47336; ACP-like; 9.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 19.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 3.
DR PROSITE; PS00455; AMP_BINDING; 7.
DR PROSITE; PS50075; CARRIER; 9.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 8.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000186583};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 835..911
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1928..2003
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3423..3497
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 4499..4573
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 5991..6065
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 7066..7140
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 8130..8204
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 9205..9279
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 10701..10775
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1901..1925
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 11276..11300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11276..11291
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 11300 AA; 1244279 MW; DF51EA619BE23805 CRC64;
MTTTREQPTN LTQNAGTTAE VRADGSKTPA DVTPYWRQHL VDLDATSFPI LPSHLTRPQP
GAQAEHNITY PASAQNEWDS TAVCRAALAV LLARYTHESE ALFGVAVERP PRSEGQGRMA
NGPARTVLPT RVFCDPRQSA SDLLRAVAAH DAAVREFAYA DLDTVRRSGD FGPAACDFQT
VLEVTSSKRG SSDPLVGSTP LPTRTAVGSG GFTPCPDRAL SLHCHVGENS VSIFASYDPS
VLDSRQASRF LRQLGHLIGH FRRRGLDLPL EELDIITAED RAEIESWNST QPLRREVCIH
DLIAQRAAET PDSPAVCAWD GEWTHAELDR VSSRLAGYIQ SLKLGAGLAV PLCFDKSKWM
VAGVLAVLKA GRAFAMVDPL HPAGRVAQIC RQTAATVALA SELNRDKFDG LVPTTIVLGD
DLLRSLPGDG EQGFTPVAKP NDLAYIIFTS GTTGEPKGAM MEHRAFASCA LEYSPAAGIN
KETRSLQFAS YAFGASLIET LCTLMQGGCI CIPSSHDRMN DITGFIKRAR VNWSTLTPSL
VATLPRDSIS GLKTLLSGGE PFLPYQRDAF ASRMQVLNGY GQSETSTMVA GPRVYENTTD
LQNIGRALGC RFWLTEPNNP GRLAPIGCVG ELLIESPGVA RGYVVPLPPD QSPFLDVAPA
WYPKGWRRQQ QLNCRFYRTG DLVCYRPDGT VACLGRRDSQ VKIRGQRVEL GDVDSHLRNV
LPGHLTPVAE TFKRTQEASS IVLAAFLFGP LKSEEAAHVG KEAYILENTS AQRIRASLKP
VLPEYAVPTY FIRMEKRPTI VTGKTDRKRL RSVGAKLVEE LIQSAVSSQP GAALGEPASV
EDHLRQMWFR SLQLPANSNS QGANFFELGG DSIAAIKLVN MAKSVGLELT VTEIFENPTV
EGLAAAIRHE PTRRGDPITA APYQGPVELS YAQGRLWFLD QLNRGSSWYL VPFAERLRGP
LQTEALAAAL YALKQRHETL RTTFEEHDGV GMQVVRESHA RELRVVDLSS APGTYEEWLR
REQTTPFDLT TEPGWRVTLL RLGQEDHVLS VVFHHIISDG WTVDIVRKEL GIFYAAARRG
EDPSAALVPL PIQYRDFAVW QKQEAQVAEH QRQLEYWTEQ LVDSSPAELL CDKPRPAILS
GDAGEIDFVI DGALFESLQA FCRVHHVTPF AILFAAFRAT HYRLTGAEDA TIAAPVANRN
LPELEDMIGF FVNTLCLRTV IDNEQTFHGL VQQVRSKSTE AWEHQDVPFE RVVSALLPGS
RDPSRNPLSQ LVFALHSQQD LGRIRLEDLR DESLPTVTTT RFDLEFHLYR EQERFRGSVP
FSSDLFERAT VGGVVDIFLE VLRRGLDRPE TRVATLPLTD RMTELHKMGL HSVEKTNYPQ
NASLVDLFRE QVAARPKAIA VTDTSSVKLT YAELDQQSDE LAGWLSQRQM APETLVAVLA
PRCCQTILTF LAILKANLAY LPLDVNTPLG RVEAILSAVQ GHKLVLLGTG TPTPEIQVPD
VEVVPIADAL SEAADTRRPS DAAAVKPQAT SLAYVMFTSG STGQPKGVMV EHRGIVRLVR
QSNVNSKLPP AARVAHLSNV AFDASTWEIW SALLNGGTLV CLDYFTTLDS KALEAVFVRE
QIQAAMLPPA LLKQCLTNTP AMLHGLDLLF AAGDRFDGRD AIATKALVRG SVYNAYGPTE
NTILSTVYEV SEQDSAFANG VPVGRAVSNS GAYIMDADQQ LVPVGVMGEL VVTGDGLARG
YTNQTLNRDR FVQVSIAGQL LRAYRTGDRV RYRPTDGQIE FSGRMDQQVK IRGHRIEPGE
IEQAMLSHSA VLDAAAVVRR FEGEEPEIIS FAMVRDDSAV VNHNLGRDTN ELPNGDNRDE
EFEILMEQQI WQRLKSVLPP YMIPARIIVL NQMPLNANGK VDRRELSRRA QTAPRRGAAS
GQKSAPVLPR NEVEAALCEE FAEVLGGTVV GITDNFFDLG GHSLMATKLA ARISRRLEVR
MTVKDIFEQP ILLDLAATLR QGSTRHSAIV SRPYSGPVEQ SFAQGRLWFI ERLYPGLTWY
HTSFATRLRG PLSLEAIGAA LLALEERHEG LRTTFRQDDG VNVQIVQPFT PKQLRIVDIP
GASEEELSQA LQKETSTPFD LENEPGWRPA LLRLGAQNYV LSIVMHHIVS DGWSVDILQR
ELVVFYAAAL AGQDPLSKVN ALPIHYRDFA LWQKEESQQA EQERQLAYWK KQLDGSQPAT
LLCDKPRPSL PSGTADMHEF IVEGAIYQDL QRFCKEHQTT PFSVLFAAFR ATHYRLTGVE
DAAIGTPIAN RNRQELEDLI GFFVNLQCIR TALAEDETFE TLVKQVVSAT AAASANQDVP
FDRLVAELQS GTRDVSRHPL VQMTVAVHYQ ENLGHVQLGG LDSEPLDVAK TSRFDLELHF
FQQQGDRLRG VIMFSNELFD PASITLMEAV FHEVLRRGLA EPSVPIASMP LTDGLSALND
KGLDQVARTE YPRDASVPAL FHEQVALHGD AIAVKDGVSK LTYLELDRQS DQLACWLAQR
GLAPETLIGV LAPRSCEAIV AMLGILKAGL AYLPLDVNEP LGRLESILSS IETKKLLLLG
NGVPVPATQL ADVEFLTIAE ARDSQLVTQQ DVAKRLPMPT ATTLAYVVFA SGSTGRPKGV
MVEHRGIVRL AKNTNLQTPT QSTGPVGHIA NLAFDAATWE IYTALLNGRS LVCVDNATVS
DVATLGRVFE QEKIRAAMFT PALLKQCLAE SPSTIKGLDL LLASTDRLDV QDALAAQSLV
KGGIINALSH TENTVYSTAF QMQPGELCIN GVPVGRAVSN SAALVLDPEG RLVPLGVMGE
LVLTGDGVAR GYTDPSLDEG RFIEVTVHGE TMRAYRTGDR VRYRPRDAQM EVFGRMDQQI
KIQGFRVEPA EVEQVLLKHP AVRDAAIVVR KHENREVELV GFVAAREEQV TQDAQNEVSN
QVEGWGNHFE TSTYVDIDKI DQTDVGKDFM GWTSMYDGTD IDKGEMQEWL DDTMATILDG
QPAGRVLEIG TGSGMILFNL GEGLESYVGL DPSSSAVAFV RNKIRSVPAV AGKAQVLVGT
ATDVAGLSGL QADVVVTNSV AQYFPSAEYL LQVIEGLIHI PGIKRLVFGD MRSWAINHDF
LAARALRTLG PSATKKEIRR KIAELEEFEE EFLVDPAFFT GLASRFPDRI WHVETLPKRM
KATNELSAYR YQAIVHVREP GEKIQQPVHV IRPEAWIDFK ASRLDRDGLR SLLQGSRDSQ
TLAVGNIPFS KTIVERLLAE SLDDRDAFSS TDGAAWISSI REAAGQCASL SPFDLVQLGK
AAGFRVEFSC ARQRSQNGAV DAVFHRFRPA HENSRVLIQF PTEHQGRSPS LLANRPLQRQ
QSRKVESQIR EYLQALLPPY MIPAQITVLD QLPVNASGKV DRRELTQRAQ AEPRARTATD
HVAPRNEVEA ILCEEFANVL GTVIGITDNF FDLGGHSLMA TKLAARLTRR LEARVSVKDI
FDWPALADLA ARIQQGSTKH NLIPSRPYSG PVAQSFGQGR LWFLHQLELG DSSSYHMPIA
IRMSGPLQID ALRVALHALV QRHETLRTTF EEHDGVGVQI VQPVSNNKEL RVLEIPDGRY
EEILAQEQTR PFDLASEPGW RVALLRLGAD DHIISIIMHH IISDGWSFDV LQRELSLFYA
AALRGQDPLS QVSPLPIQYR DFSAWEKEEA QVAEHERQLT YWKEKLAGSQ PATLMCDKPR
PATISGNGGL IELSIEGPVY ESLQEFCRTY QATSFTVLLA AFRAAHYRLT GDGDATVGTP
IANRNRSEVE DLIGFFVNTQ CMRIAVDDDQ TFAALVRQVR STATFAFENQ DVPFERIVSA
LLPGSRDTSR NPLVQLIFAV HSQKDIGKIQ LEGLTNENLP FTPTTRFDLE FHLFQEEERL
RGTVFYSTDL FEATTVQAVV DVFQEVLRQS LDQPKVPIAG LPLTDGLPAL RSMGLLQVDK
TDYPRNSSVG DVFLEQVAAH PESIAVKDAS SQLTYAQLNE QADRLAAWLR QRKLAAGTLV
GVLSPRSCET VIAFLGILKA NLAYLPFDTN VPTARLKEIL SEVSGDTLVL VGASVTMPDL
GLPSVNLVRI AEALRHSRSK EEGVDALSAP NADSLAYVMF TSGSTGRPKG VMIEHRGIIR
LVKGTHPHMQ VEAGVSSAHV SNLAFDATTW EIYSPLLNGG TLVCLDQMTV LSPSLLHEAI
RTNNISVAFF ATALLRQYLE EMPSIISNLD ILFTGGETIR PKDAFKAREL VRRAFCHAYG
PTENTDYSTL YVMRPDERCS NGLPIGRAIK NSGAYVMDSR QQLVPLGVIG ELVVTGDGLA
RGYTDPSLNA NRFVQVTVDG QSVRAYRTGD RARYRPADGE IEFIGRTDNQ VKIRGYRIET
AEVEQALAGL TGVRDSAVIV RKFEDQQPDL VGFVTVNVHV KQDQADSEDG ESAAAGTANV
TERDIRQRLQ AALPSYMVPA QIIVIDHLPL TVTGKIDRRE LVRRALTAPR AKTVSLRVAP
RTEVEAVLCE EYAKVLGMEV GITDNFFDLG GHSLMATKLA ARISRRLDAR VSVKDMFDQP
VLVDLAAIIR KGSALHKPIT PMPYYGPVEQ SFAQGRLWFL DQLNTGALWY LIPLAARLRG
PLNVDALNVA INALQERHET LRTTFVEQDG IGVQVVHPPC SKELKIIDLS TNRDSGSYVQ
PLHTEQTTPF KLDSELGCRA TLFKLAEEDH VLSIVMHHII SDGWSVDVLR KEISTFYAAA
LRGEDPLSRV NPLPIQYRDF AAWQRSDIQA TNQKKQLEYW TEQLADSTPA EFLCDKPRPA
ILSGDAGVVQ LSIKGDLYES LQTYCRANHS TSFAVLLAAF RATHYRLTGA KDATVGTPIA
NRNRPELEDV IGFFVNVQCI RTVVQDDETF DSLVRQVRAT ASAAFENQDV PFETVVTALQ
PSTRDPSRSP LVQLMFALHS QHDLGRIPLE GLASDLIPSP PTTRFDLEFH LFQEEGQLGG
TVLFASNLFE AATVSSLVEI FLEVLRRGLA QPDTPIASLP LTDGLASLYS AGLVNVEKVE
YPRESSVVDV FAEQVAANPD VVAVKDSSSQ LTYSQLDRLS DVLAAWLRQQ NLAAETPIAV
FAPRSCEAIV GFLGILKANL AYLPLDVNVP TARLTSILSA IDGNVLVLVG STVEKPTVDL
PNVSMVPIGD ALRDAPADIS SQGFSRPSAT SLAYIIFTSG STGKPKGVMI EHRGIVKLVK
HSNVVSKFPP AARVAHLSNI AFDASVWEIY SALLNGHTLV CIDYFTTLNP LALNSLFLQE
QINMTILPPA LLKQYLKPLA PALGALDLLF VGGDRFDGQD AAAASRALVS GTLYNLYGPT
ENTVISTMYE VCEQDSFVNG VPIGKAVTNS GAYILDPNQQ LVPVGVMGEL VVTGDGLARG
YTDAALNKGL FAQVAINGQV VRAYRTGDRV RYRPTDGQIE FFGRMDQQVK IRGHRVEPAE
VEQALLNQSD VTDAAVALRR QDGEEPEMIG FVTVRGDQSL EKDEASNQVE GWGNHFETGT
YADIETIDQS AVGNDFLGWT SMYDGTEIDK GEMQEWLDET MVALHDGQPA GRVLEIGSGT
GMILFNLKGL EGYVGLDPSS SAAAFVNSKI QTVPSVAGKA QVRVGTAMDV GTIDVQANLV
VTNSVAQYFP SGDYLFQVIE HLTRLPGVER LFFGDMRTLA INKDFLAARA LRDLGPDATR
EQVQRRVVEL EQREEELLVD PAFFTGLTSR LPDSIWHVEI LPKRMEAINE LSTYRYGAVV
HVRNPEDKHP QQTVHTIKEE SWIDFKKSHL DSPGLLSLLQ GSKNAQNVPV ANIPYRNSIV
ERLLVESLDD DEEAQRSVDG AAWISAIRDA AGGYACLTAA DLVRIGEQAG FRVELSSARQ
RTQNGALDAV FHRHQPANKH NRVLFGFPTD HDDQLPSLLT NRPLQRHQSL RIETQLRERL
QAVLPPYMIP AQIVVLDKLP LNANGKVDRR ELTRKARAVP KTKTSPTERV EPRNEVEAVL
CEEFSVVLGV EVGITNNFFD LGGHSLMATR LAARISRRLN TQISVKDIFD QPVIVDLAAT
VRKGSSKHNA IKPQPYNGPV EQSFAQGRLW FLDQLQLGAT WYVMPLAVRL RGPLQVKALS
VALQALEQRH ETLRTTFEEH NGVGVQVVHP YRPKELRVVD VSANQSGGYL EALQKEQSTP
FDLVTEPGWR PALLRLNDQD HILSIVMHHI IYDGWSLEIL YRELDTFYAA AAQGQDPLAR
VVPLPIQYRD FAVWQKEEAQ VAEHERQLSY WREQLQGSQP ASLPCDKLRP AALSGSADVV
SITVEGSTFK NLQAYCRARQ ATPFTVLLAA FRMAHYRLTG AEDATIGTPI ANRNRSELED
LVGFFVNTQC MRITIEEEGE SFETLVQQVR ATVNAAFENQ DVPFERIVSA LQPGSRDTSR
NPLVQLMFAV HTHQGSGSIQ LENVASELLP NAVTTRFDIE FHVFQEKGRL TGKILYATDL
FTSKTIRGLA DVFQEVLRRS LEQPEAIISS LPLTDGLDKL QSMGLLSIPK TKYPRDASVV
DVFCEQALNH PDAPAVIDAS STLTYSQLDQ QSEKLAAWLR LQGMADETLV GVLAPRSCDT
IVAFIGILKA NLAYLPLDVN VPAARLEVIL STIPGRKLVF LGAEVSAPDS LPAEVELVRI
GAALKHSHRN PSTASRPSAT SLAYTMFTSG STGKPKGVMV EHRGIVRLVK NSNVVSKLPK
AARVAHLSNV AFDAATWETY APLLNGGTIV CVDYFTVLDN KALLALFKRE QVQAAMFPPA
LLKQCLANAP ATLDSIELLF AAGDRFDARD AIEADSIVPG SVYNAYGPTE NTILSTIHQV
SKDDLYVNGV PVGQAVSNSG AYVMDVRQRP VPIGVMGELV VLGDGLARGY TDSALDAGRF
VNITIDGQPS VRAYRTGDRA RYRSDGQIEF FGRMDQQVKI RGHRVEPAEV EQAILRHTAA
SDAVVVLRTQ EGQEPEVVSF VAVRYTNGVA AEHAETAREA FASNTEKQIQ QKLQTVLPPY
MVPAQIIVLD QLPVNANGKV DRRLLAHKAQ TTSNTTNAAN VSTRVAPRTD VESVLCEEFA
DILGVDVGIT DSFFDLGGHS LMATRLAARL SRRMHARVSV KDVFDHPVLA DLASTIQQGS
DQYSPMVPAP YTGPVEQSFA QGRLWFLEQL ELATSWYLVP LAVRFRGRLD VEALDTALQA
LEKRHETLRT TFEDNDGIGM QIIQPSRAKS LRLIDLSVSD ESAYLKALSQ EQTTPFNLSS
EPGWRVALLR LGDEDHVLSI VMHHIISDGW SVDVLRKELG AFYAAALQGA DPLSRVNPLP
IQYRNFAVWQ KQEAQVAEHE RQLAYWKKQL DGSQPASLIC DKPRPNILSG EAGVVQLKIT
GDLYESLQAF CRSRYTTPFA VLLTAFRTAH YRLTGSDDAT IGTPVANRNR PELEDLIGFF
VNTQCMRIAI EGEEETFEGL VRKVRSTAIS ASENQDVPFE NIVSALLPGS RDTSRNPLVQ
LLFAVHSQKD MGKIQLDGLD GENLSITPTT RFDLEFHLYH EEGGLGGTAL YATELFSPET
VQSIVDVFHE VLRRGLEQPD ICLTKLPLTD GLPALGRLGL LKVPTTNYPR QSSVVDLFRE
QVAAHPTAVA VTDTSSKLTY AELDEQSNML AAWLCQRKLP AETLVGVLSP RSCQTIVAFI
GILKANLAYL PLDVNAPAAR IETILSTLPG RKLVLLGSAV VAPEPPLPDV ELASLTDVLA
AAVEHNHAND SARPHANSLA YVMFTSGSTG KPKGVMVEHR GIVRLVRQST VVSKYPPAIR
VAHLVNIAFD MSTWEIYSAL LNGGTVVCID YFTTLDPIAL NTVFLEERVQ ATMMAPALLK
QCLAHMAAAF RDLDLFFASG DRFDSCDAVA MQALVGGTVY NAYGPTENTV LSTLYEVVEE
PFVNGVPIGK AVSNTGAYIT DAHQQLVSLG VMGELVVTGD GLARGYTDPE LDKNRFVQIS
VDNQLVRAYR TGDRARFRPL DGQIEYFDRI DHQMKVRGHR IEPAEIEQAM LGHPAVTDAT
VVRREQEDEE ADLVGFAVAQ DLAADTDAAA QTEKSILRRL QTLLPSYMVP DQVIVLGQMP
LNSNGKTDRR ELARMAKVAP KDKEASTRIA PRNDVETALC EEFADILGVE VGISDNFFDL
GGHSLMATKL AARLGRRLHT RVSVKDVFDH PVVADLAATI QRDSMRHRPI DASEYTGPVE
QSFAQGRLWF LEQLDVGATG YLVPLAVRLR GPLQLKALSA ALYALEQRHE TLRTTFEDHD
GLGVQVIAEP GRAGRINLVD VQAGEDFMER LGQDQKTPFD LSSEPGWRVT IFRIGDHDHV
LSIVMHHIIS DGWSLDVLQR ELATFYTAAL QGKDPLSQVS PLPIQYRDFS VWQKQEAQVA
EQDRQLAYWK EQLDGSQPAS FLCDKPRPTK LSGEAGFVDF RLEGAAYGNL QAFCRAHQTT
MFTVLFAAFR ATHYRLTGVE DATIGTPSAN RNRPELEELI GFFINTQAIR TAVPDRRTFR
ELLAQVRSAV SAALEHQDVP FERIVSTLLP GSRDQSRNPL VQLMFTLHAQ KDLGKVQLDG
LKDEQLNMAP TTRFDVEFYL AQQEGRLGGG VLFSTDLFET ETIRGIVNVF QEVLSQGLAQ
PDAPISGLPL SYALPELRQM GLLDMETTEY PRDASVIDAF SEQVVARPGA TAVTDASSSL
TYRQLDQQSD QVAAYLQHRH MVPETLVAVL APRSCQTVVT ILGILKANLA YLPLDVNVPA
ARVEGILATV PGHKLVLLGT DVTALTTESP EVEQVQISHA LSQGRALVPL DARLRLSVTA
KSLAYVIFTS GSTGKPKGVM VEHRSIMRLV KSTNVISQSQ AARPVAHISN LAFDAATWEI
YAPLLNGGTV VCIDHMTVLN PNALGQAFAA NSVSAAFVTT ALLKQLLDEV PSIISGLDLL
LSGGEAMRPK DASKARELVR QTFCNVYGPT ENTTFSTIYP MNADDCCANG VPIGRGISNS
GAYIMDPGQQ LIPAGVVGEL VVTGDGLARG YTNSALEKDR FVQIKVAGRS IRAYRTGDRA
RYRPTDGQIE FLGRMDQQVK IRGHRIEPAE IEHAMLSIDT VIDAAIVIRK QGQDSEIVGF
VAARYTNGVT ASPDESREKE QHFALDTERE VRRRLQVLLP PYMVPAQIIV LDQLPQNANG
KVDRRELAQR ALTAPRGSEH SIRVAPRNEV EAALCDEYAD LLGVKVGITD SFFDLGGHSL
MATKLAARIS RRLDARITVK DVFDKPVLQD LAAFIQLGSK LHKPIESTPY SGPVEQSFAQ
GRLWFLDKLN IGGASYIMPI AVRMRGPLQI EALKTALHGV EQRHETLRTT FEEHDGVGVQ
VVNESRPKAL RIIDVSNESN ETVDGSFHFL QKEQRVPFNL ASEPGWRVAL FRLGEQDHIV
SIVMHHIISD GWSVDILRND LASFYAAALR GQDPLALMTP LPIQYRDFAA WQKTEDQVAE
HEKQLEYWTK ELTDSSPAEL WNDKPRPAMP SGNAGVIEII IDGPLYESLQ AFCRSRQVTP
FAVLLAAFRT AHYRLTGIED ATIGTPIANR NRPELEEMIG FFVNTQCMRI VVDDESFEGL
VQQVRTKATA AFENQDIPFE RVVSALLPGS RDTSRNPLVQ LMFALHSQRD LGRLKLEGLD
SEPLPPPTRT RFDLEFHLFQ EEGYLAGNVV YATDLFEPET ARNLNDVFQE VLQRGLTQPE
TPITSLPLTN GLATLRSMGL LDVEKTDYPR ESSIIDVFLE QVAAHPERLA VKDASSQLTY
AQLNEKSDKL AVWLQRRKMA AETVVGVLAP RSCQTTIAFL AILKSNLAYL PLDVNTPAAR
LKSILSALPG LTLVLLGNDV PPPNVRLSDI EFVPLAETLA LSRQSLAGAP SRLSLPSATS
LAYVIFTSGS TGRPKGVMIE HRGVVRLVKQ TNIVRELPDA TNISHVSNIA FDASAWEMYT
ALLNGATLIC IDYFTTLDSR ALEAVFAREN IRVAMLSPAL LKQCIANIPA TIEALDILYV
GGDRLNLSEA TAAQALVKTG VYNAYGPTEN AVASTIYKVE EGKHFEHGVP IGRAVSNSGA
YIMDSQQQLV SIGVVGELVV TGDGLARGYT DPALDRDRFV EVAIEGRRVR AYRTGDRARY
RPTDGQIEFF GRIDQQIKIR GHRVEPAEVE LAMLKHAVVR DAAVVIRSQA GQDQEMIGFV
TVQEEESLQD EASKQVEGWG THFEIGTYAD LETIDQSAIG NDFLGWTSMY DGTLIEKAEM
QEWLDETMVA MLDGQPAGRV LEIGTGTGMI LFNLGQGLEN YIGLEPSSSA AAFVRDSIKS
VPALAGKAQV HVGTATDVNR LVQGAEARTD MVVTNSVAQY FPSADYLLEV IRALAQLPGV
KRLFFGDMRT YATNRCFLAG RALHSLGENI SKEGVRRKVT ELEENEEELL VDPAFFTSLL
RQIPDLVWHV EVLPKRMKAT NELSRYRYAA VVHVRGAEKP TQTVHTVSPD AWVDFQASSL
DRDGLFALLQ DSPNASTVAV GNIPYSKTMF EQLLVESLDN DDEAQDSIDG AAWISAVRNA
AERRVALSAS DLAQLGERAG FRVELSWARQ RSQNGGIDAV FHRLEHPSNK GSRVLFQFPT
EDQGRPARLL TNRPLQRLQS RKVEAQIREQ LQTLLPPYMI PAQIIALDQM PVNANGKVDR
RELTRKAQAA PVGKPSSERV EPRNDVEAAL CEEFTDVLGV EAGITDNFFD LGGQSLMAAK
LATRISRRLG VHVSVKDIFD QPLPMDLANK ILDTLLQGGS NGKSHLVDSE PFQLLSQEDP
ETFVQHELSS QLDLSGSRIE DAYPATWTQK IYLKHFITEQ SLDPTIIFLD FPTNAELTTV
KKVSRAMVQH FDIFRSVFLL AAGKFYGVVL DQLEVPTDVI RVETDMASAV AGVIDADRRD
PLRLGQSLIR IAILVKQATP VRMMIRMNHA VYDGLSFEHI LRAVHALYIG EHLPTPPKFS
RLVQYMMNSR EEGYKFWRSV LQGSSMTIMK GAEKKNGRLR QGEEQESQEG TLYSEKIIKA
PHHTNVDGIT PATVFTTACA LMLGSELDSN DLVFGRVVSG RQCLPPSSQH MVGPCANAVP
VRISLGATTR PRELLRKVQE QYVNSLPFEA LGLDDIRQNC TDWPESTSHY SCYTAYQNFD
KHARDGKGDQ LIQLNYPEAD TPTWEVSEED PTLVRYSWND IPMHDVDIVG TPEPDGIHVK
VVVGVNRRLC DTSTVDRMVL KLCDMIGMLD SILQYPLPEI PGGNATQTLN GDAKKRVNGD
EKQRVKVDAQ PISEGDDIQI
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