ID A0A1Q8S2A4_9PEZI Unreviewed; 1964 AA.
AC A0A1Q8S2A4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Iterative polyketide synthase CazM 5 {ECO:0000313|EMBL:OLN95511.1};
GN ORFNames=CCHL11_05125 {ECO:0000313|EMBL:OLN95511.1};
OS Colletotrichum chlorophyti.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum.
OX NCBI_TaxID=708187 {ECO:0000313|EMBL:OLN95511.1, ECO:0000313|Proteomes:UP000186583};
RN [1] {ECO:0000313|EMBL:OLN95511.1, ECO:0000313|Proteomes:UP000186583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NTL11 {ECO:0000313|EMBL:OLN95511.1,
RC ECO:0000313|Proteomes:UP000186583};
RA Gan P., Narusaka M., Tsushima A., Narusaka Y., Takano Y., Shirasu K.;
RT "Draft Genome Assembly of Colletotrichum chlorophyti a pathogen of
RT herbaceous plants.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLN95511.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MPGH01000035; OLN95511.1; -; Genomic_DNA.
DR STRING; 708187.A0A1Q8S2A4; -.
DR OrthoDB; 5396558at2759; -.
DR Proteomes; UP000186583; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 2.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 2.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR013217; Methyltransf_12.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF21; NON-REDUCING POLYKETIDE SYNTHASE AUSA-RELATED; 1.
DR Pfam; PF18558; HTH_51; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF08242; Methyltransf_12; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186583};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1964
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012209433"
FT DOMAIN 241..636
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 1449..1530
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1964 AA; 214409 MW; 3330D182626D51BB CRC64;
MTEAAELGAI AVRLALCTAA FVDLDQLESA EPVVCISARY PRSMSDGREG TGEGGPELFK
ETMENYQQAY TSVRIDATSA TITATRGVAK SLMRDLEDHG VMVKEIDLKG RFHYPGHADA
LRKLVQLCTC TPMLQFPEHK RPLIPLRQNI NGAVVSDEIP LHETVLRSIL TDTADWHTTM
AMVMAATVDS QGADTGEAGS PARLLVQLGP VDCVPRSVLT ATTFRVLQST TNETMHYGYP
DDAIAVIGLS CRFPDAETPK QFWDVIRGGK KTSNSFPDVG SFDCGLFRKS PREAEYMDPQ
HRLGLHLAYE ALESGGYFSP SSSSTDNVGC YVGMSSCDYE DHVNARPPTA FSFTGTARAF
ASGRISHFFG LTGPSMVIDT ACSSSGVAIH TACKAIQSGE CAMALAGGIN LMTPEGQAHQ
NLAGASFLSP TGQCRPFDIG ADGYRRGQGG GFVLLKRLSA AVADNDRILG VLTASAVNNS
KGSRSITLPS SESQSSLYQQ VLRSANLHPR YVSYVEAHGT GTQKGDPVEC QSIRNVFGGD
RRAGCSPIRF GSVKANIGHG EAASGIASLI KVLLMLQHGL ITPQANFSAL NPAIPPLDEA
NMEIAVEIAR WKGPCRTALI NNYGASGVNA AMVVRQPPST RTHQALSAAA TPRRFPFLVT
ASTAVALQRN CRALLHFIKT QVGSLDDDNL PSFAFHLAQR QNHTLTHRVV FSAASVADLH
TQLLAQVEGK NAVGGADARN PTVGPKPVVL LFSGQTGRRA HVNRDAYLSL PLLRRHLDRC
DRILQSLGLH SLFPRMFDAE PVGDLVDLHC MQFALQYSVA ASWIDAGLEV KALVGHSLVT
HAFHSRLVDD ILPDYYRLLR GLVFHPATIP IEPCSEPGGG WDSVTPELVG RQSREPVYFA
QAVSRVEERL GSCIWLEAGS GSAAITMTRR ALEGQQSHGV PAHSFDAVQL HGSDPISSLA
DTTLGLWNKG VRVQFWLYHA SQRQSFVPMD LPSYQFEKTQ HWLPFIERHK GPERESQGQP
QSLQEPLDLV SLIGNADATD AKAFEFSINQ NSDEYSLFVR GRTVFGHILA PGSVYAESAA
RAFTLLPTHT TSADQSLAPV ELSQLKLHAP FGIDLQRRLR LILRRLTASC WDFVVESRPL
HNDPSKPAKL QASGSIRLQG PDNSHFGASQ RLLRRLHDRC DELRDDPSAS VVQGAYVKRI
MGRVASYDDR YFGIRFIASR GLEAVGDVEL LPIESECRAG IALSPPVFDN FLLVAELHAG
SLGDLAEDHL YICGGFDAII PHISSSEDSS SQPEGPWTVL STLERDNEKT VTSDILVFDA
RKKTLFLSIL GAKLTQIPKR SLQKVLEEIN VSGPAKIKDD LDTTDKMLQV DSWGATPQSS
FASTPTINTK AGLGIADYLH PDFSNRQIHH ELHSVLSPAH DSTTSSQLTS TDHTKESLGF
VAEPSVTPAS SAPSEHDQSS AVLYNLLAEH LDCSNGIPPD MPLGNIGLDS LVAIQIQSDL
ERLFGKSPSL KSIDERTTFL DLCSMVLQPD LTSQLESKSF AVNSTTTKST SNTLQGMDHS
FADAVPVVAQ TPVLSQGPSA YLTLAVGEFD RVKKETGVFA QQTEFAGFYA GVHQKQASLV
VAYILEAFSA LGCDLRSLGA GEPVPTISYL PKHQKLVSRL CEILEEAEII SASDSQLFRY
RTDAPLPPST PSADLYRDVL TEYPRYQPDH QLLNVTASRL ADCLSGRADP LQLLFQDRKS
LALLEDVYVS SPMFSMGNNM LGEMLRGLLS HSMFQRNSAE KLRILEIGAG TGATTRRVLD
QLLACDVDFT YTFTDISLAL VNSSKKKFSD RYGRQRVQSD MEFMVLDIEK PVPVNMLQSY
HLVISSNCIH ATKDLRQSCA NIEKLVRRGN GILCLLELTR PLGWLDCVFG LLDGWWRFED
GRIHALAHES DWKARLQNAG FRNVDWTDDG SRESQHFRLI TAWH
//
