ID A0A1Q8YKA3_9BURK Unreviewed; 2152 AA.
AC A0A1Q8YKA3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=BLL52_0318 {ECO:0000313|EMBL:OLP08393.1};
OS Rhodoferax antarcticus ANT.BR.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Rhodoferax.
OX NCBI_TaxID=1111071 {ECO:0000313|EMBL:OLP08393.1, ECO:0000313|Proteomes:UP000185911};
RN [1] {ECO:0000313|EMBL:OLP08393.1, ECO:0000313|Proteomes:UP000185911}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ANT.BR {ECO:0000313|EMBL:OLP08393.1,
RC ECO:0000313|Proteomes:UP000185911};
RA Baker J., Riester C., Skinner B., Newell A., Swingley W., Madigan M.,
RA Jung D., Asao M., Chen M., Loughlin P., Pan H., Lin S., Li N., Shaw J.,
RA Prado M., Sherman C., Li X., Tang J., Blankenship R., Zhao T., Touchman J.,
RA Sattley M.;
RT "Genome sequence of Rhodoferax antarcticus ANT.BR, a psychrophilic purple
RT nonsulfur bacterium from an Antarctic microbial mat.";
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLP08393.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MSYM01000002; OLP08393.1; -; Genomic_DNA.
DR RefSeq; WP_075584970.1; NZ_MSYM01000002.1.
DR STRING; 81479.RA876_15610; -.
DR Proteomes; UP000185911; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR Gene3D; 3.30.190.20; -; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 3.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SMART; SM00382; AAA; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 3.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000185911};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SOS response {ECO:0000256|ARBA:ARBA00023236};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 702..1048
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 216..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..248
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2152 AA; 231896 MW; 84DF52343222DC0E CRC64;
MTQGTIRIRG ARQHNLKNLN LDIRTGELTV VTGPSGSGKS SLVFDTLFAE GQRRYVETFS
AYARQFLDRM DKPAVDKVEG VPPAIAIDQT NPVRSSRSTV GTMTELNDHL KLLFARAGQL
FDSATAQPVR HDTPETIYAE LLRRTAAFSA GLPEGEAARW EGREPGPVGN VATTDPRLAI
TFPVELPAST TPEEIEQWLS VSGFTKVQAE RVVELGSDPD LGHQANGKPK SSSKSGSDPN
SARAENSSTR KVLDVIADRF RLSAVERARA LEAIEVALKH GSGRLSVYVL NQPLALMYKA
LVATDVVATE PPDIWRFSTG LHCPDSNLRY TDPTASMFSF NSAVGACDSC RGFGRVIGVD
YGLVIPNEKL TLRAGAIKPM QTPAWKEAQD DLMRHAEAEG IPRDTPWNKL NAEQQHWVIN
GSPHWKGKWN LHWFGIKRFF EYLESKAYKM HIRVLLSKYR SYTECPTCAG ARLKTESLLW
RIGTQAQADD VLAPAKRFLP SGVKWSRAQL EALPGLCLHD LMLLPIDQLR RFFDAMQLAQ
VGAGKATEAN AKTLKLLLEE ICTRLRYLSE VGIGYLTLDR QSRTLSGGEV QRINLTTALG
TSLVNTLFVL DEPSIGLHPR DMHRIIVAMQ RLRDAGNTLV VVEHDPAVMF AADRVIDMGP
GPGQQGGQIV FDGSTADLRN ADTLTGAYLG GRKQVGMGFK RLVAANTPRL ILEGACDHNL
KNVSVEIPLQ RLVCITGVSG SGKSTLVQDT LAPALLRHFG KASEAPGAFA RLLGAELLSD
VVFVDQSPIG KTARSNPASY VGAWDAVREI FATAPVSKQR GYTASKFSFN SGDGRCPTCG
GSGFEHVEMQ FLSDVYLRCP DCDGKRYRPE ILEITIERGE RHLNVADVLE LTVSEAAILF
ASDREVIRGL QPILDVGLDY VKLGQPVPTL SGGEAQRLKL AGFLADASKG SSASRQALAR
KGVLFMFDEP TTGLHFDDIA KLMRALRKLQ DAGHSLLVIE HNLDVIRASD WLIDLGPEGG
DAGGEVVAFG TPEEVMLHAS SHTGQALRDY AAQMGVVHVV AEAPLAYASM GRAAADGLAP
GASYVSFAAS KSLPGASPSA AGVGTPTNPS NGGRIPISVK KLSSDPHCVV NSAEAFVVNP
LSKSELSAHV SKGLEANNSI QIINAREHNL KGLSVNIPRG EFTVVTGVSG SGKSTLAFDI
LFNEGQRRYL ESLNAYARSI VQPAGRPEVD AVYGIPPTVA IEQRLSRGGR KSTVGTTTEV
WHYLRLLFVK LGTQHCIYDG TPVAPQTPES IAAQLMKTFR GQHIGLLAPL VMNRKGVYTE
LAEWARPRGF THLRVDGNFL PTTAFPRLDR FKEHTIELPV FSLDITPANE SLLRQALADT
LQHGKGVLHV LSGLDGLSQA MQTGAPTAGI GKLSVFSTLR ACPVCSTSYA ELDPRLFSYN
SKHGWCPDCV GTGVKLTREQ RKVFDDSVRD DYTSGREQTF TEADVDDLVN AVCPNCNGTR
LNATARAVKF GDVTITELAR LSVTDMRLWV EALQVQGRMS QRETDIARDL VPEILGRLKF
LEQVGLGYLT LDRGAPTLSG GEAQRIRLAA QLGSNLQGVC YVLDEPTIGL HARDNQILLG
ALRHLSDQGN TLVVVEHDED TIRAASHIID IGPSAGKRGG RLVAEGSVAD IQNAAESQTG
RYLLHAMRHP VQARRVVANT EFIATSAMDT RARGQFDDVT VEHAALAMSG DISRAMLVVQ
PDSTSGGAAA AKFGSDVKFV FVPAPKKKKV AKKLDSDPNF ADHEPQRWIT VQGARLHNLA
NVTVQVPLKR LVAVTGVSGS GKSTLARDVM LANVQTAVQK RSTKAGRDAL AVGEVIAWTG
CDSVTGFEAV DRVLEVDQTP IGKTPRSCPA TYIGFWDTIR KLFADTLEAK ARGYGPARFS
FNTAGAGGAA ASGGAGRCPS CEGQGIRTIG MSFLPDVKVL CETCKGARFN PETQAVTWRG
KNIGDVLQME VDEATAFFAA MPVIAHPLQL LKDVGLGYLT LGQPSPTLSG GEAQRIKLVT
ELSKVRDDIT RRGQKPPHTL YVLDEPTVGL HMADVEKLIK VLHRLVDGGH SVVVIEHDLD
VIAEADWVID LGPDGGNAGG RVVAAATPEG VVKLGTHTGV ALAGVLARGV AQ
//
