ID A0A1Q8ZJ29_9CYAN Unreviewed; 1874 AA.
AC A0A1Q8ZJ29;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=BST81_01450 {ECO:0000313|EMBL:OLP20127.1};
OS Leptolyngbya sp. 'hensonii'.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Leptolyngbyales; Leptolyngbyaceae;
OC Leptolyngbya group; Leptolyngbya.
OX NCBI_TaxID=1922337 {ECO:0000313|EMBL:OLP20127.1, ECO:0000313|Proteomes:UP000186296};
RN [1] {ECO:0000313|EMBL:OLP20127.1, ECO:0000313|Proteomes:UP000186296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=hensonii {ECO:0000313|Proteomes:UP000186296};
RA Hamilton T.L., Klatt J.M., De Beer D., Macalady J.;
RT "Physiology of photosynthesis in the novel isolate Oscillatoriales
RT cyanobacterium hensonii.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLP20127.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MQTZ01000003; OLP20127.1; -; Genomic_DNA.
DR RefSeq; WP_075596766.1; NZ_MQTZ01000003.1.
DR STRING; 1922337.BST81_01450; -.
DR Proteomes; UP000186296; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000186296}.
FT DOMAIN 16..283
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1694..1868
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 1504..1531
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1874 AA; 209063 MW; 194C9406E6293561 CRC64;
MDTVNPDNHS PPLEGYRLTQ LLHAGSRSLV YRGIRLTDEL AVVLKFSQDA RPWLQDLLQL
RNHYIITKNL NLPGVVQPLG LEPYGHGFVL VMADEGYIAL SDYIKAHPLN LAEFLAIAIQ
LADILHHLYQ HRVIHKDIKP ANILIHPESK HIQLIDFSSA SLLPKETEDV KPPSILEGTL
AYLAPEQTGR MNRGIDYRTD FYALGVTFFE LLTGQLPFRS NDPLELLHGH IAKPAPSVCE
FQPDIPPGMG QIVAKLLAKN AEDRYQSALG LRYDLNQIRH RWEQSEDIEA FELGSRDMSD
RFLIPEKLYG REFEINTLLH TFSQVSQGIT ALILVKGFSG IGKTAIVHEV HKPIVQQRGY
FIQGKFDQFN RNIPFSAFVQ AFRNLMGQLL SESEAQLQVW KSQILAAVGE NGQVIIDVVP
ELEQIIGAQP EAMELSGTAA QHRFNLLFQK FIQVFATAAH PLVMFLDDLQ WADSTSLHFL
QRLIAELETG YLLLIGAYRD HEVSPVHPLM LTLETLSQTQ AKITTIALPP LSLSSLNHWV
ADTLNCSQAL AQPLTELVFQ KTQGNPFFAT QFLQSLHQDG LIEFDLQAGH WQCDIVRVRE
AALTDDVVEF MTLQLQKLPP ATQAALKLAA CIGNPFDLAT LAIVRDPRDG NTSEQSEIET
ATVLWAALQQ GVILPLSEIY KFFQEGADIG REPTSEFWML DSATCTYRFL HDRVQEAAYS
MIPASQKEAV HLQIGRLLLE RIPPNDRELQ LFQIVNQLNH GITLIRTGRE REELAHLNWR
AGAKARAASA YEAAMNYLDI GIQLLSPQSW KHQYSLSLRL HHLATEVAYL CGAYDRMAAL
ITAGLQHSNN HLDRAKFYEI QILALVAQNQ TRAAVDYARH VLPNFGVQLP QNLSKPRILL
GFFATLYRMA GKTPRDLLTL PVMLDPDKLA ACTLINAIGA ATERGLPEIL PFITFTGISL
YLRYGNIPKS SLAYTIYAFL LCEKLGRVDA GYAIGKAAIA LCHRTSSKAA LASTLFLWNR
FIAYRKESLS STLQFLLEAY QVSLEVGDVE YAAYSLCFYF SQAFWAGQNL VDLRKEAIAS
RPTFQKLQQQ AMAALQDLNC QGLDNLTTDT GDACQLVGRF FDETAITAAD GHLQAYTSIR
KLQLACLFRR YAMAMEQIAI VETRLGAIEG TFNKSLFYFY AALVRLGQYP NLPPKQQRAC
LNKVKAALKH LSRLAKSAPM NYQHKACLVE AERLRVLGQM SPAEDRYDRA ISGAKAQGYL
QEEALANELA AQFYLDRGKE KIAQVYLIEA YYCYARWGAV AKVTDLEIRY PQLLLSVLQP
ERAVSPARTT SSTYISHGPQ ALDLETLLKV CQAISGEIEL DQLLATLLTI VITNAGADKC
VLLLQTEQGL QIVAQVETGQ QPHILPSPTP LDLSPNVAIG LVSWVQRHLE PLVLSHGRQN
PQFVRDRYLI EHQPKSVMCS PIMNQGQLLG VLYLENNLMV DAFTHDRIEL LNLLCTQAAI
SLENAQLYHQ LEQANLQLAE YSQTLTDKVA ERTQELSQAI IHLQSTQQEL IQSEKMAALG
QLTASVAHEI NTPLGVICGA TANIMAAFET TLRKLPPLLQ QLSPQQQADF LALVNRALQQ
QHPPSTQAER QLRQQLQSQL ADRGLAEAPR IASQLTLLRL GTDFDPYQSL LFDPNAVAIL
ETAYNLVLQH QNAQSIQQEV DRAAKIVFAL KTYSHPAKSG EKSLVAVTES IEVALTLYHN
RLKQGIEVIR RYAPGVANIL CNPDELTQVW VNLIDNAIYA MGEQGILEIT VTQQTDRVVV
EITDSGCGIP AELQSRIFDP LFTTKPRGEG SGLGLDIVRQ LLHKHAGEIQ VQSQPNRTTF
TVGLPLLMTE GQPG
//
