ID A0A1Q9CG17_SYMMI Unreviewed; 1924 AA.
AC A0A1Q9CG17;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Tubulin--tyrosine ligase-like protein 5 {ECO:0000256|ARBA:ARBA00041448};
GN Name=Ttll5 {ECO:0000313|EMBL:OLP81826.1};
GN ORFNames=AK812_SmicGene37576 {ECO:0000313|EMBL:OLP81826.1};
OS Symbiodinium microadriaticum (Dinoflagellate) (Zooxanthella
OS microadriatica).
OC Eukaryota; Sar; Alveolata; Dinophyceae; Suessiales; Symbiodiniaceae;
OC Symbiodinium.
OX NCBI_TaxID=2951 {ECO:0000313|EMBL:OLP81826.1, ECO:0000313|Proteomes:UP000186817};
RN [1] {ECO:0000313|EMBL:OLP81826.1, ECO:0000313|Proteomes:UP000186817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP2467 {ECO:0000313|EMBL:OLP81826.1,
RC ECO:0000313|Proteomes:UP000186817};
RA Aranda M., Li Y., Liew Y.J., Baumgarten S., Simakov O., Wilson M., Piel J.,
RA Ashoor H., Bougouffa S., Bajic V.B., Ryu T., Ravasi T., Bayer T.,
RA Micklem G., Kim H., Bhak J., Lajeunesse T.C., Voolstra C.R.;
RT "Genome analysis of coral dinoflagellate symbionts highlights evolutionary
RT adaptations to a symbiotic lifestyle.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-glutamate + L-glutamyl-[protein] = ADP + gamma-L-
CC glutamyl-L-glutamyl-[protein] + H(+) + phosphate;
CC Xref=Rhea:RHEA:60144, Rhea:RHEA-COMP:10208, Rhea:RHEA-COMP:15517,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:29973, ChEBI:CHEBI:29985,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:143622,
CC ChEBI:CHEBI:456216; Evidence={ECO:0000256|ARBA:ARBA00036640};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:60145;
CC Evidence={ECO:0000256|ARBA:ARBA00036640};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLP81826.1}.
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DR EMBL; LSRX01001246; OLP81826.1; -; Genomic_DNA.
DR OrthoDB; 275962at2759; -.
DR Proteomes; UP000186817; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd06974; TerD_like; 2.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 2.60.60.30; sav2460 like domains; 2.
DR InterPro; IPR049452; Anoctamin_TM.
DR InterPro; IPR003325; TerD.
DR InterPro; IPR004344; TTL/TTLL_fam.
DR PANTHER; PTHR12241; TUBULIN POLYGLUTAMYLASE; 1.
DR PANTHER; PTHR12241:SF145; TUBULIN POLYGLUTAMYLASE TTLL5; 1.
DR Pfam; PF04547; Anoctamin; 1.
DR Pfam; PF02342; TerD; 2.
DR Pfam; PF03133; TTL; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR PROSITE; PS51221; TTL; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186817};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1805..1829
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..157
FT /note="TerD"
FT /evidence="ECO:0000259|Pfam:PF02342"
FT DOMAIN 191..358
FT /note="TerD"
FT /evidence="ECO:0000259|Pfam:PF02342"
FT DOMAIN 1794..1914
FT /note="Anoctamin transmembrane"
FT /evidence="ECO:0000259|Pfam:PF04547"
FT REGION 601..623
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1003..1030
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1171..1202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1219..1242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1302..1321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1506..1526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1573..1604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..618
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1302..1319
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1924 AA; 213941 MW; A96F402063C1781D CRC64;
MCALKHAEDL ALKSSRYGVA VSWDLEGKAV DLDLQAVVVD ERGCIVDAVY YNNMKALKGS
LTHSGDEQTG QKEGFDEVIW ANLPKLPENI RLLIFVVAAY SGGSLRDAKN GKLHVLEGNK
DCQVACFALE QSIYAVDAVA SILRTDSGWH MQIIEEPARE GRHFIDILEP VLGNIIRAAI
PGAPKRQKVA FAMEKASVVD LPQAESLGTV QACLGWDVSP DAGVDVDLDV SAVVVGGDGQ
VRGAVFFGEL EGWALTHSGD NLTGEGDGDD EVITANLQWI PADIHQIVFV VNVYTRGVTF
EKVSNAYCRI LDSSGEEMAR YVLREGRGER GLIMARLFRE GGGDGERWGF QALGSFCKGQ
TWKDSVPDIQ ALARKTARQL QMRSGTMSFA QESTSEPAVV ATPMKSEDSP KSGACDDAGL
SPITACETHP CPFAAFLKQG GPRKPSPKLQ AKFRLSGGGL QPRSAMSAYT KGEYEQLDAA
SGRGVDSPEV PMRRFYEVCM VFQHKTDKRF AFDEQENEFH RALPPAGPED HTKMQADTEG
NHMLYWLENN EDSYVSTTVV PKNMCATRAQ GKDSARSALL QLRAKGRMLQ LMQQPTRDLW
QKVPGYTSDE DEELASREPT PSQLEGRLAE VLLAASSRGL DRPMMQFRPV PFSGSRACSQ
SGAKSRSPGV PAFLLNAADA PLLQETFLHN GMVPTLGNDY VIQWSGPNIK DAVYQSMTEW
QRINHFPGST ELTRKDRLWH HFAEMARNYG KQCFDFVPET YVLPEQFDEF LTCYQRTRCT
WIVKPNSSSR GRGIFILQDL SELPVDETVV VSRYIMNPLL IQGLKFDLRV YVLVTSFDPL
KAYIYREGLT RFASAPYSTE ADHMQDAFRH LTNYSINKNS CTFVENSDLR CDNVGHKWSL
SALNKHLRCV GVDVDLMWTR IMDLIVKTLM SVEPAISNRT RQVLAGRENC FELYGFDVLV
DDELKPWLLE VNLSPSMQAE SPLDWQIKSS LLADTFNIVG VSSPERGTPK DRARNHAQPW
KQAGNGKGEW AKEDIPVDEN LPPVVLNALP DSALKMIAKS IGERARCRNF VSLYPTRAAV
KRYGIISEGR MQPGSFSRSG FPTAPLSLSQ ILASILYGPA PLRSATEMIR PDLRAEGSRV
EDKTEAMQAV RALPEGSTQR EWHRPRAVAD KESILGPKEP LSGQVPVPVS PLPPSVADPG
SSLEDREYAL MAARRTLRSL SGKTSRSKAD LQPEDLGQAD EKPLPISSVN MASCLLLMEY
LMRMKAACDN LGPSACARLA RSASYARLSN FHRQLPSAAK AFNDASSSSS SSSDSPQAKE
GSLIEDLGNA CRDSLDVLER FAWQEVDADW ELHEERDSKP RDNLPSSRAR MLSKRLPKAF
EKSKECKKLL KVLPELRAAD LESLLRGHAA SGLPSSNDDV CSMLECFRTS EEQEDGKDFQ
RSLPGGLWQA ASSPNLARAN SQVLPTIGAE SRGGGCDRGE IPCGPLSEIL TAAAAAHVEP
CRPCRRPHLS GRRSPPKHRG LSSSSFASWP RLSSAKSLPP AAVMKEVTAS LANRIVMPVP
NFMSTGIRRR SKPRALPELL PEVRVPAEGR HGSRDASTSP RDSSAARAAL TARFDIELCL
SCEPGMWKQH RESILKTLQN CGLNLYCFYS RDRDQILVKI GAGAQKLRDT AARKRYKLQL
KKEYLSAFAE FRHDYPGRPE FRFADRRIIS HIYQTHTEDN LDGSGIFKTV DKIQLISHII
QSKDKDCAGI NVAKLLHQKE VKAFFPLHEQ SVMDKIKSLQ FKWFWPDEEH ANRLRDYFGD
KITFYFLWMA FYVKWLSPLA CLGLFLQFID WCARTPDNVT AIPFCVLMSI WSLCLPHFWR
RQEAKCAISW GSMDLVEQLE PHRPEHTGEQ LINPVTSQAE PHYPLSKRIF KLPVLLPAFA
QEAS
//
