ID A0A1Q9CIW4_SYMMI Unreviewed; 2345 AA.
AC A0A1Q9CIW4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Kinetochore protein NDC80-like {ECO:0000313|EMBL:OLP82845.1};
GN Name=ndc80 {ECO:0000313|EMBL:OLP82845.1};
GN ORFNames=AK812_SmicGene36461 {ECO:0000313|EMBL:OLP82845.1};
OS Symbiodinium microadriaticum (Dinoflagellate) (Zooxanthella
OS microadriatica).
OC Eukaryota; Sar; Alveolata; Dinophyceae; Suessiales; Symbiodiniaceae;
OC Symbiodinium.
OX NCBI_TaxID=2951 {ECO:0000313|EMBL:OLP82845.1, ECO:0000313|Proteomes:UP000186817};
RN [1] {ECO:0000313|EMBL:OLP82845.1, ECO:0000313|Proteomes:UP000186817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP2467 {ECO:0000313|EMBL:OLP82845.1,
RC ECO:0000313|Proteomes:UP000186817};
RA Aranda M., Li Y., Liew Y.J., Baumgarten S., Simakov O., Wilson M., Piel J.,
RA Ashoor H., Bougouffa S., Bajic V.B., Ryu T., Ravasi T., Bayer T.,
RA Micklem G., Kim H., Bhak J., Lajeunesse T.C., Voolstra C.R.;
RT "Genome analysis of coral dinoflagellate symbionts highlights evolutionary
RT adaptations to a symbiotic lifestyle.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore
CC {ECO:0000256|ARBA:ARBA00004629}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NDC80/HEC1 family.
CC {ECO:0000256|ARBA:ARBA00007050}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLP82845.1}.
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DR EMBL; LSRX01001161; OLP82845.1; -; Genomic_DNA.
DR OrthoDB; 38726at2759; -.
DR Proteomes; UP000186817; Unassembled WGS sequence.
DR GO; GO:0031262; C:Ndc80 complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR GO; GO:0051315; P:attachment of mitotic spindle microtubules to kinetochore; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR Gene3D; 1.10.418.30; Ncd80 complex, Ncd80 subunit; 1.
DR Gene3D; 1.10.4190.10; Urease accessory protein UreF; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007751; DUF676_lipase-like.
DR InterPro; IPR005550; Kinetochore_Ndc80.
DR InterPro; IPR038273; Ndc80_sf.
DR InterPro; IPR002669; UreD.
DR InterPro; IPR002639; UreF.
DR InterPro; IPR038277; UreF_sf.
DR PANTHER; PTHR10643; KINETOCHORE PROTEIN NDC80; 1.
DR PANTHER; PTHR10643:SF2; KINETOCHORE PROTEIN NDC80 HOMOLOG; 1.
DR Pfam; PF05057; DUF676; 1.
DR Pfam; PF03801; Ndc80_HEC; 1.
DR Pfam; PF01774; UreD; 1.
DR Pfam; PF01730; UreF; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Centromere {ECO:0000256|ARBA:ARBA00023328};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Kinetochore {ECO:0000256|ARBA:ARBA00022838};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000186817}.
FT DOMAIN 894..1040
FT /note="DUF676"
FT /evidence="ECO:0000259|Pfam:PF05057"
FT REGION 239..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 293..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 376..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1213..1291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2005..2025
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1452..1583
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1669..1710
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 381..400
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..434
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1242..1256
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2345 AA; 261772 MW; 164F1C5B179D8E2A CRC64;
MFQARLIAGA WDVQQGQAAL EMLRGWLRDP RPPFVLKQFA AFFAVWQKEA LEEQLRVPVD
VDDIVGTHVS ELLIVASGPL WEERCLRDQA LEVILEHCKV LQPEPRREAF ASVLLRLGRS
AGTQAVAEVA LSCRAEATPL AEVLKRGLAA FWARFPEEVF SAVAFLVRTA LRIDDAEAFV
DSAPGLREEA DVEDLGFVVL CLLVFWLVAR DSSTQDDTID AASTGLTQLT GLPLEAMAEM
EEKDEEEEKA KDEKPKDEEA PEEEEPDVSA FRPGDSVITI RRRMQKARKE QMEQAAMERR
SRTPSPMGRH KLRSFASSGR PDLEDAAIEA FEAAAGRRVE VADSKQRPRK VERFHQDLIR
KEVWRQKFDY IFKQMQEQEH EEEEEEREEE EEEEQEEQEA GVEIELQKDR KSRRPSILQQ
KGKEEAEDAE ARRQKAVAGL SQSEMEQELQ QLRRASAPGS PLAIARVAGK LMSLKTEPGL
CSDGFGYHYH HPAADSSDED LLSTPDSASA SLPSDFVFLD PADNDAVEAP TASERSQPSV
QGFEDPVLEA KRESFTEELV KHLCLRHLQH QLQQDFSSRQ AAAQLREFKR RHETAKARSL
QNYVAQHLEP ERKQDMEHMV GAVRIMLEED TPENDLSWMQ SLANGPLPNQ TILLQTMQRA
MYDGLQPTVG NRSANMVAGL EDKRLQIQQW IIAYRVSAVE ADRVEQATCE PRQEFEAPVS
PEVVQRTFAR LKPEDVHAMS LADRVQLAKL LRPLFKADAS EGKVCAVKKC KKTKDVHNLR
DPRLVKAAGD LGKMKRRNLP LEKGVYTHVL RLLSADMSPA TPLCVKEIGS LETSSASAGN
RFSADGVLIV VVPGHTYIPP SSLEDLCDQL QLLLPEDMVW VPSMSKIPDG VQAALKEDDL
DFAALQLAQE VSAKLDAIEK EIGKSFSLSF WCLGTGGLIA RAALAWLTSR HEKLLTFISL
GTPHLGLFVP GLSWWYWWRV AVWRSCSSSP LWLEQVMHME GRRARGSRLH RLCQSGNFLD
CFKTLVFIGS GTDSLVPLSS SALHVSSCDV SKAPEAPPDL SQPIPSSRIL LVFFPILWLA
RLRAWSSLLV VSIGILLALL LPSPPGNLGR RLRIVKLQLH DFLKTVRGEV EPELDRHFAQ
LLVSSVAEKL VKVEVWPDNS GWSWWLGQGF GSHLLSEHEW IKTLVQRYGP SLTTHRKKPQ
SFTCRVFGSE ERVTRSRPVM ASTPKQKFRP SLGEPSRVSR LRAQSPGASS VGSGEDIGTS
PRRRALFPSG TGRTRALVSS RHSRDPRPVG DRAFTAQCAK NVVELLSARG YSKTFSHDKL
LKDPSTKEFY DVFRFLIAQL DPQLEVEGKM EDEVPSIMRR LKYPVEVNRS KLQAISGPNT
WPQLLAVLDW LTVLVRINDE LIEPLAACQL GLSDVGDPDR DAGDHHVLRS LHENYLNFLS
GKDDSGDEER LRMIYMQRLE ALQSEIQRLE NQQVEMQQRL QDFQGEHDRL LELQKMPAQL
EVEADRLRSI IQAQEHKVQT IEDEMLCKEA EEREQQKEIE TLQAKRAYLA EQVESQAYSR
RDIERLHAER SHLRQLFKDL KAEGERADEE VWELGMQEKS RAEEIGRLVR QVNDTVECLT
HALTEEEADI FDFRVRVDLS EPSDALASLA FDDQKTWAQA ASSSHGERLQ QAELALHELL
EEQRGLQTSL AEKEGEARHM RARHEQLTRI YQEYREWSAS QIDDAQKTTE ATEDAVHEIS
IGSAAPSLRD AAEVDKLKLT LASVQTQGAH ERAQLEEQIR RDEERLEEHR QLIMRELDSY
AKASTALCED VEAALLVDMA VEVDPNATLT LASTKIYRTN QDLPAIQRIS VRIRKGGLLV
LAPDPLVPFA SSQYSQLMRF TLTPDTDASA GDGASAVIVD WLGAGRIASG ERWAFDEYAS
RFEFVWEEGS YDTSEGTAGG KVKRPRLVEA VRLRRDDCHF LDHPLQSFDA FVTIFACGPQ
AQRVVCRTKA VALLLAARAG ARVRSEEASR SGGGHPSGPS HISLPQTKGQ ALMGITTDEN
SGCTVIRLMA EHTEDVYRLL HVCLEPLASL LGAEPYADRV HGAGVFQIVQ TKAGPASSAE
PGHPKPALTH ELNLQQQFAL CHLTDATLPV GGFAHSGGIE AAVQLGLLSR QEGDIDGLKH
FIKMLALSAF RLQGPFVRSA HRLGAEADGV PVDLNELGEL GRLDEDLHAH LAGSLACRAS
LLQGAGLSRI GRRWCNLSGL PRNGHFASFF GLLCARLDLP QEVSVQAFLY CNVRDAVSAA
VRLNLVGPLQ AAELQRCILA DLEHLQGDCV GDESPARYCE QFCMLPSQSK LLEKASPVVH
AAGGA
//
