ID A0A1Q9D3S8_SYMMI Unreviewed; 1421 AA.
AC A0A1Q9D3S8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Protein NLRC3 {ECO:0000313|EMBL:OLP89804.1};
GN Name=NLRC3 {ECO:0000313|EMBL:OLP89804.1};
GN ORFNames=AK812_SmicGene28686 {ECO:0000313|EMBL:OLP89804.1};
OS Symbiodinium microadriaticum (Dinoflagellate) (Zooxanthella
OS microadriatica).
OC Eukaryota; Sar; Alveolata; Dinophyceae; Suessiales; Symbiodiniaceae;
OC Symbiodinium.
OX NCBI_TaxID=2951 {ECO:0000313|EMBL:OLP89804.1, ECO:0000313|Proteomes:UP000186817};
RN [1] {ECO:0000313|EMBL:OLP89804.1, ECO:0000313|Proteomes:UP000186817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP2467 {ECO:0000313|EMBL:OLP89804.1,
RC ECO:0000313|Proteomes:UP000186817};
RA Aranda M., Li Y., Liew Y.J., Baumgarten S., Simakov O., Wilson M., Piel J.,
RA Ashoor H., Bougouffa S., Bajic V.B., Ryu T., Ravasi T., Bayer T.,
RA Micklem G., Kim H., Bhak J., Lajeunesse T.C., Voolstra C.R.;
RT "Genome analysis of coral dinoflagellate symbionts highlights evolutionary
RT adaptations to a symbiotic lifestyle.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC41A transporter family.
CC {ECO:0000256|ARBA:ARBA00009749}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLP89804.1}.
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DR EMBL; LSRX01000742; OLP89804.1; -; Genomic_DNA.
DR OrthoDB; 5474824at2759; -.
DR Proteomes; UP000186817; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.357.20; SLC41 divalent cation transporters, integral membrane domain; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR006667; SLC41_membr_dom.
DR InterPro; IPR036739; SLC41_membr_dom_sf.
DR PANTHER; PTHR24111:SF0; LEUCINE-RICH REPEAT PROTEIN (LRRP); 1.
DR PANTHER; PTHR24111; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34; 1.
DR Pfam; PF13516; LRR_6; 9.
DR Pfam; PF01769; MgtE; 1.
DR SMART; SM00368; LRR_RI; 9.
DR SUPFAM; SSF161093; MgtE membrane domain-like; 1.
DR SUPFAM; SSF52047; RNI-like; 2.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186817};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 1204..1222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1281..1300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1312..1341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1238..1369
FT /note="SLC41A/MgtE integral membrane"
FT /evidence="ECO:0000259|Pfam:PF01769"
FT REGION 233..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 585..622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..260
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 585..609
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1421 AA; 157492 MW; D5DB11BA00699715 CRC64;
MFLTKGNWQI ERKLFPCAKE NVVTNLVNVY DWVMLPLEIG EQYYLTGEID LSRFPCHQMN
GSFNALSAMR KSVQWFCQGV MNEGAEHQRL CFVVRRRDVN EAKRVWTEAS SSKRMKLDNY
LNRQFTDHIS TQNATMVEND GDSNGKWIWR VPTEESKNSM GIIRMDPYDA MSYTRTGPQL
LCLSEMCDWN RLATVPRTGL IEWRLMGHTM VPAVQAAHGG LDHDCSTWDE LYEGDDGENV
HPWNGPASSS TAAPKNAVTT SQGSNATVLA HVANALTPGA EVVLRMNVNA KDQGFGSILE
PEAAFNAFLV REQKRRSPRD TRPGLTAKWA RDPPKPPVDA VPYNGLNAAY HGAGSRVAFI
HICQRPSQAQ YGLTDPKSLA EYLNHANIRL VRAECSYLYK LLKSKQLLPR RQEADPEEWG
LVTHAEVKAW AAGTRRRGAM ICSVSHAWES REHPDPCAHQ LKCLVDVVAL FDAAYFSDVW
LFYDYVSLFQ FKRESDAEEE SFRRSMQDMH VLYAHECTRT FRIENLTPDD VWEAASKNSE
YRVRVYDARS AVVRDRPLKE LVANRVPYGT RGWCKAEVEW SSARSRSERN HRIDAPESRQ
HFRDWQEDSE PEPELLENQE PERLGKVPMA PEIFEKEMDS AAFTHRSDAE EVKKLQFKVF
LQKVSECEEA LFERLPEGQL GQLAKALPYF KKLRVLRLRD FKAGRAEAGE FAKVLTSNQT
IRELEIHGPR FGFEHEYGFR REAIAAALKT NSTLISISLE SNRIGVEGCK AICEALKTNS
TLASIKLAHN NIGDEGAQAI SEVLKTNSTL TSINLAVCYI GDEGAEAISE ALKTNCTLTS
VDLESNRIGG VKGDKAICEA LKCNCKLTSI NLKGNRIGKG AVKAICEVLK TNSALTSINL
AACYIRDEGA EAICEALKSN STLTSINLEH NDISQQVLAE VRRRRPLVDV WSAEAPEAAK
AWTGRVRIEA LAKQLNVHCN PTKLSFERCA LDVERVEAIC EALKSNSKLT SINLTWCYIG
DEGAQAICEA LKTNSTLTSI NLKSNRIGVE GGKALAKALM RHNRLEIELY GNKIRVDCEE
ALSEATGGRP GGVQAEVFLI LIPIFVRVTM TSVEDIHEGL CVALREHGLQ DLGVPAVAQA
IVREVCPNGL ILVDILGFEE VRQAHVNAGC LQRQVVPAEG TREGEQQAWD EHNKPAWRRA
VSRMPALLVT LVIELFVALI VTEYTDTFKK YTLLIAFQPV ISALSGNVGL QTMATITRGL
VIGIFNGRET LRGMRHEVKS GMVVAALLST VVAAVAFAWY NPFSSGHSFL GTLAFGFAIF
LGQFASSISA SVTGSLAPLL FNKRGWDPAA LGGPLETAFQ DVIGSSVMLA ASAAVLAQFG
DHAESCPGGD VKRCASLCKE GPSYNEQCLQ HCLDLALKGL C
//
