ID   A0A1Q9D970_SYMMI        Unreviewed;      1290 AA.
AC   A0A1Q9D970;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Soluble guanylate cyclase gcy-35 {ECO:0000313|EMBL:OLP91762.1};
GN   Name=gcy-35 {ECO:0000313|EMBL:OLP91762.1};
GN   ORFNames=AK812_SmicGene26502 {ECO:0000313|EMBL:OLP91762.1};
OS   Symbiodinium microadriaticum (Dinoflagellate) (Zooxanthella
OS   microadriatica).
OC   Eukaryota; Sar; Alveolata; Dinophyceae; Suessiales; Symbiodiniaceae;
OC   Symbiodinium.
OX   NCBI_TaxID=2951 {ECO:0000313|EMBL:OLP91762.1, ECO:0000313|Proteomes:UP000186817};
RN   [1] {ECO:0000313|EMBL:OLP91762.1, ECO:0000313|Proteomes:UP000186817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP2467 {ECO:0000313|EMBL:OLP91762.1,
RC   ECO:0000313|Proteomes:UP000186817};
RA   Aranda M., Li Y., Liew Y.J., Baumgarten S., Simakov O., Wilson M., Piel J.,
RA   Ashoor H., Bougouffa S., Bajic V.B., Ryu T., Ravasi T., Bayer T.,
RA   Micklem G., Kim H., Bhak J., Lajeunesse T.C., Voolstra C.R.;
RT   "Genome analysis of coral dinoflagellate symbionts highlights evolutionary
RT   adaptations to a symbiotic lifestyle.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OLP91762.1}.
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DR   EMBL; LSRX01000650; OLP91762.1; -; Genomic_DNA.
DR   OrthoDB; 46655at2759; -.
DR   Proteomes; UP000186817; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   Gene3D; 3.90.1520.10; H-NOX domain; 1.
DR   InterPro; IPR038158; H-NOX_domain_sf.
DR   InterPro; IPR011644; Heme_NO-bd.
DR   InterPro; IPR024096; NO_sig/Golgi_transp_ligand-bd.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR45655; GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2; 1.
DR   PANTHER; PTHR45655:SF13; SOLUBLE GUANYLATE CYCLASE GCY-35-RELATED; 1.
DR   Pfam; PF07700; HNOB; 1.
DR   SUPFAM; SSF111126; Ligand-binding domain in the NO signalling and Golgi transport; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186817};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        814..833
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        870..892
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        904..921
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        933..956
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1001..1021
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          423..584
FT                   /note="Heme NO-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07700"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          357..395
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        358..395
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1290 AA;  143224 MW;  8C42A51665A99DEC CRC64;
     MRSIPEVERL NMDGARDAAK EAARACAEAR KESNTATCAD PTEVYASNRR MPIDDDVDRK
     RIKQDLVKES EKDAMRTCME ESDKTGFDRC MGELAEPDEV AGELFRGLSD ARKQNKEKRA
     KEDAAVEVVG ERFQICMEAA TSDGQKKDCH DAMRAGAGMA GLKEDVEDVM KKFQRNTVGM
     AARACNETQR PMCIEQAKEE LKKSGLKAEL EEISGSMSIW TAEVAEKVKA LGEAMLEGRE
     IVLRKLQAIL LETLTDALNC SDAVLDKLAE KAQQTSDGFM PNATMGPRNV SHKECKIVWG
     LARYYCKVHT KDLNETETED LSDSLGTEVG TTDIDAANDR RLGLGRRLAV ITDSYAAQEE
     EETASTAGDG TSATTTTTTT TTTTSAGMGS TSTSHSMVTS PFETLGHLMK PCLLRMQIPY
     TMYGWIQETI EALVLEKFGS EAWQKVKLEA GLASFPTGGF ARNEYYNDAF TMNLVSALCK
     VCKLDKESAL ICFGEFFISW LMDHGYASML RNQGSNMFEF LSTVDDLHQG LQKGLPELLP
     PRMICRKGSD ATLSLEYISC RSGLAPMVIG MVRQVGRQLF HSDYSCMMEV QKQSEGENGK
     ALEHTFFKIA CISGRALDQA LGEASELQEE DSFDADSECS LKSSARDIEN YDFLQQNPTM
     AGAFSYILVE RVKLLDCPLK SQHFGHNFEF AQLMSLMASY SPEAAVALSG LFRQPLSDPT
     KCTPVPRHAC ISGPGGRDGL FTKSYDTIVM NPSIFSGQDP LLPVELSVCV IPDPLRSGQM
     LKSLANTPND DVLATTAAQA LLDAAWALTR SRKIFDITCE SIILLFTCSW IFFREHRGLW
     PCLVFCLMKE FVEKGIETVR SWKKGWSVPL ALVAGTALNI SLYVILIYQA MISDDYPSDR
     MGQIAIAVFG CTRWWSLLAH LRGFKAIGSK ILPILYALGS MGPFLLVFGI IMLGFLSSFC
     ALSDEALTMT RVRGIYFLAM LGEDGDTVLD GAREEWWLDS WVFLFVVVMC LVLLNILIGI
     LGEAYDMYRD SAEVIFSRER ARVTLSVTMR LLPMAWPEHC GNNLQRLFLS VFTENTCGRH
     KKYLWAVVPQ DHSLNVARIT SMKEHVSRES ERAVQAAKVT QQRLEQLERD WKSWKHPLAK
     CPFSGAPLAS GCQPSSGHKR LDVPGQSSCG DEFTVDSIKT YELSQVQDTS KHETPVEKLV
     YLEAIDSLVC LSRGCRSFRL YEPKRCTLKH NVPGHRGSVI NCCYVDAWSQ IATTAADMTI
     CFWDSHLQLR NRLAAKACGR SHALSSNLKC
//