ID A0A1Q9DC02_SYMMI Unreviewed; 3651 AA.
AC A0A1Q9DC02;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN ORFNames=AK812_SmicGene25401 {ECO:0000313|EMBL:OLP92773.1};
OS Symbiodinium microadriaticum (Dinoflagellate) (Zooxanthella
OS microadriatica).
OC Eukaryota; Sar; Alveolata; Dinophyceae; Suessiales; Symbiodiniaceae;
OC Symbiodinium.
OX NCBI_TaxID=2951 {ECO:0000313|EMBL:OLP92773.1, ECO:0000313|Proteomes:UP000186817};
RN [1] {ECO:0000313|EMBL:OLP92773.1, ECO:0000313|Proteomes:UP000186817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP2467 {ECO:0000313|EMBL:OLP92773.1,
RC ECO:0000313|Proteomes:UP000186817};
RA Aranda M., Li Y., Liew Y.J., Baumgarten S., Simakov O., Wilson M., Piel J.,
RA Ashoor H., Bougouffa S., Bajic V.B., Ryu T., Ravasi T., Bayer T.,
RA Micklem G., Kim H., Bhak J., Lajeunesse T.C., Voolstra C.R.;
RT "Genome analysis of coral dinoflagellate symbionts highlights evolutionary
RT adaptations to a symbiotic lifestyle.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLP92773.1}.
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DR EMBL; LSRX01000607; OLP92773.1; -; Genomic_DNA.
DR Proteomes; UP000186817; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR007125; Histone_H2A/H2B/H3.
DR InterPro; IPR000477; RT_dom.
DR Pfam; PF13202; EF-hand_5; 2.
DR Pfam; PF00125; Histone; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186817};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1181..1202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1214..1233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1276..1297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 3492..3520
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 3628..3651
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 625..668
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1071..1129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1360..1406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1507..1553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1920..1950
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2251..2277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2314..2363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2378..2411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2600..2657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2765..2786
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..661
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1364..1388
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1531..1553
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2335..2356
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2378..2394
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2619..2649
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3651 AA; 397464 MW; DFCE3EDE6F4EF665 CRC64;
MLKQLPHEAI GPLTELLNQV EQTGLAPGQW SITKFVMLAK NQAIERPIGL CSVAYKAWLQ
MRYPLVQAWL QGYEKVAPWD AAVPGVTCLS VSIARVFKCE VAVATGCHRA TLYLDLSTFY
ETLSHAKLIE SALALDFPAS VLNIALQIYR GGRIIDAEGN MGPISFTDRG VIAGCPAAPA
LSKLALYQPL KTVQEAGLCA GLDSWIDDVT IDAEDKDPQR AAQKIVSLYR TVSAELGHAE
LKISTSKSAF VCTDRQTQSR VQQLLREGEP PVLHLVKDLG VDSAGARRRR VATSNARLAK
ATGRSGKLVR LKVPNPKKRA QVATTGVFTA ATFGHQGQGI SPKRMKVLRA IAGGHYGKMA
FGSLDLLFDL SWMGSGDPLC KIVLEHWSMM QECVARNRPA SSLIRRTWEV SWHKLSRSPH
RWKLAAGPIG AMQCYLMDMG FEAPTMDEWK RPGTHINLAW GSSQVGKEVR EQLNQAMLVD
RWHRISCQES AAGTEEGIDW TVPRKMLKES VKHPFQHAGL RMLFQGAIRR ANSGGDMVCS
RCGQTNTLRH VLHDCIRWAE VDIGPDPEWQ SLFPQAPDCF KAQLQVRKTG IFTGEFLPDD
NVYFGTDASG ITDNIDRAAR ATCSISRSKV PLPPPPPPRR GTSSKASAYQ PRETNEQTGG
GPHGGPSGVL LNYIARGSDK LAFESDGLVL KLSEGTQREE LVFSGKLPSV TATTYWIEKI
QVHLHKEDGT VWHNYTLFLS CQEKAVRASD LMSSRGETWA FRFLAYVGCL LTWLTARGCD
KLFVSLKLEL KKMAGVTSQG LAILVHVLAG FVDFCDMWMW PAAHFRNESD ILRRYCIVCA
KWRLRSSSPI PRLGVMAASS PKVTAGASQA LPRACIPLIG YPCAFLPGSV PAIMHVPAAA
AAAGTAYTGK WLFDYNRANF QYDVPQRFGR FMTSRGMLNT QVGQYRQDVH GIAELTSSKM
DTVQGMMTLV LCVCAALSDA GRIGMHGCAP PQWLVGLYSG HIYTSILYCG TALWLGMHGS
LRAQCAMTSL LTRKVRLPIP SMAQLDAARS FGSAFEQQKF GDIFRVPFMR HPEDAPELPP
ADPGDSGEDD DDKNDKKEKG SKDGKKPGKK KASKVHLPDP RTEFSSTARD TVPSWIRDEQ
VVDKGGGLLG LPSRDDFEPH ETPDHFKMLL AAQEEWWQYD VYARVLMLYG SCQFLYAVCY
YCIGTTTAEL RGFWISWSMP MLFMAAQVLI LRLDVVRTSG NHMLPNAEWI GHLAPYFAVT
ATTLEYRHLY SPTTVILTWV FVFLTYFAHI VMAMRFLDLA WPDWNRATDM PDEPGKPWWP
SSWKVPSAFR NALWLLAPPK KLEPGQHDLL HEAEGLQSTG GGAEIRRRGK DKKGKSGGKV
KEVGEGLVSD EAGESSPTTY RGEAEGAYTG RSPFKAFAEA RSPDLPWQLA RVAICTVGGL
WLYMGIALFV EMNVGPDTLM KPPGEPPWIR DQKMKNVWVP KGWHMSSEPL PSDYRLESST
LAKYEEGSVG GFNPDDIHSP GVGESGVQES HGSEHGGEHG GHESHSAHRR LAGEDGQLLR
DLLKATDGLA WLHDSLKEIE ANQAAPLYEL PPSPAVPFMA PTVLNAKKVK WPSLFEPHHL
LCRGSQLMAL TSRGFGAHLA NLDDEEVDAA PFALEGLGAV RSLVGGAWLD EGLQLITKVG
ELFDCPGVAP MKGRWSCKNS TMKLPLPHGS QLLAAAISKT EESGHIAALL FDHAPATVNL
FHGASGSWTS AGEVHLPSDA GHVGLSISGQ DLLALLGTNG AVLRRHIVKG RPSMEALAEI
TVWGNFLPAY KPPDSRRHPE LESFWHFRAS KEIVCSTDYV LPAPADEIDP IDALRDAVSQ
WRVHSDWFPG LRRLVRDVFG DRTRLVQGVE HATRNMKKND SQGRARARGI LPRFRPRRAR
GRGRGRMRGR GAREAVPHDE GQQQEPVPIP PHLTSRGLPV FLAYFYESIF IPSALGFSLF
WRTCKLRMEE GWGERIWVQY FFAQYMKQEA FRQEILWGAS WHAGSVGRHE PGLPPSQQTA
EQAWRMLKRC LRAKPVRTHL ELADRIETVM KHWSAPVPDN RNRPCNKRPA ATMFLMPVGR
DVSLIRPHSP HQWMISGEGR TVRRPGGWQQ YIPSIGTIIR KSQLRGGASV QRLQRGRKIF
MCMSVGKCTV VPANLLQRML EQIQARTEAD LSRLWLQEGF IVDDDQGGPR RINLTAYRTV
WRKFCLLSLD LDGERCMRTW YEPLAMVRGA EQGPQMHDSD DAKRSLSTPS LLQSRRTQRH
LRSSLRVPYR LPWNCKNQRQ SAEVASVLSL SSAEKDPKSG SRAGKAGAAC KAETEPWPDL
RRRLARTGRD SDDSSSEQVD MQSGMLGALE AEAKEHQVTV KEKAKDRQAD MGELEEAEEA
PEEERCPGVA PQKVARQLLA AQGHLQDRVA RDAESVLKTL PKKGRRGNDL RDQVRSMFHE
NHDKLSIWPN TFVRLLRDTF RSIVAEEADR SDWRRAEFLE TMRLDTRAMA ALHTVMEGVM
QEIMRQSGEL AEHGKRVTVY KEDLQLALRM REQLGDPMAA GVVRRVFGPE PRELDERERE
RDLAVRARCR QNMDMLSDIL HEGKELGRRS RKPAKNLRRQ RESKATAPSE KDVPHTNASR
LKDTALSEKD VPHTTASQLK AALPGHCVEE EPLLDPATAP SKADFSRKTV SQLKATGRKD
ELVPDLRVPV RWAGVIANLE FVNVARKNKR GPSLPALFAD CAPTLVLESN AIANAEKPDA
DITKTDAHAG STTWHPSPPA TQMPREYRGA CSKDSEVGGL IRLAIRQAAP KTEAWLPELS
LVPLPAGSRQ QVEYEEQDLE PEYVERIVEV PRVRVDHVER YPKSRWWTES WKFLKFKMLW
KQMGDMEDRG VEDLASAELA WAEAQATGLE RDTVQVMVRD VVVVVVGQED ADLAATDLVE
AVGLTAGDLV AMHQEDVGLA PTDPVVVADL VVAGLVVADP AVADPAVADX XXXXXXXXXX
XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX GGPGGCGPGG CGGPGGCGPG
GCGGPGGCGP GGCGPGGYGP EGGVNFAFTG GAVDVGSSTG RYPYYGDEGA SRFGGGGSFG
GGGFGGGGFG GGPCGLSGGP GGFGGGGMGG MGGYGPGRAG PRGLGAAGRG NLPVKVITRE
VPKVEVKQVE RVVEVPNIEY EDRLVEVREV REVVRRVPRI EVREIPIERV IQVPKKIVQE
VETPVYRPVP HLVKQQVERE IPIPKPYTQT LEVVKQVSVP TNESGAVLAQ SSVAPQTAQV
ASVPPAVVHA PSVSRTYALP AVPSTGSACM STPTDKTPVA TVAPSMPYAG QMQTLPAQVP
PSAVGAATPP AMYPASALAT SSTAGRSMCA SVGSMAPGTV QTGIVAPAVA SMAPPALPSQ
PIQTYTQGSI AYPAYPSVMV ASAGGASAAG AATPPMAPSS AVLQGTGNLS QAANPFATVQ
GGLVPQAQAG SDLFSRLDAD GSGTITREEF EKATSTNVAG SGIMYASVGS MAPGTVQTGI
VAPAVASMAP PALPSQPIQT YTQGSIAYPA YPSVMVASAG GASAAGAATP PMAPSSAVLQ
GTGNLSQAAN PFATVQGGLV PQAQAGSDLF SRLDADGSGT ITREEFEKAG F
//
