ID A0A1Q9DE93_SYMMI Unreviewed; 2888 AA.
AC A0A1Q9DE93;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN Name=mcm9 {ECO:0000313|EMBL:OLP93536.1};
GN ORFNames=AK812_SmicGene24550 {ECO:0000313|EMBL:OLP93536.1};
OS Symbiodinium microadriaticum (Dinoflagellate) (Zooxanthella
OS microadriatica).
OC Eukaryota; Sar; Alveolata; Dinophyceae; Suessiales; Symbiodiniaceae;
OC Symbiodinium.
OX NCBI_TaxID=2951 {ECO:0000313|EMBL:OLP93536.1, ECO:0000313|Proteomes:UP000186817};
RN [1] {ECO:0000313|EMBL:OLP93536.1, ECO:0000313|Proteomes:UP000186817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP2467 {ECO:0000313|EMBL:OLP93536.1,
RC ECO:0000313|Proteomes:UP000186817};
RA Aranda M., Li Y., Liew Y.J., Baumgarten S., Simakov O., Wilson M., Piel J.,
RA Ashoor H., Bougouffa S., Bajic V.B., Ryu T., Ravasi T., Bayer T.,
RA Micklem G., Kim H., Bhak J., Lajeunesse T.C., Voolstra C.R.;
RT "Genome analysis of coral dinoflagellate symbionts highlights evolutionary
RT adaptations to a symbiotic lifestyle.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLP93536.1}.
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DR EMBL; LSRX01000577; OLP93536.1; -; Genomic_DNA.
DR Proteomes; UP000186817; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11630:SF48; DNA HELICASE MCM9; 1.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00493; MCM; 2.
DR Pfam; PF17855; MCM_lid; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS50051; MCM_2; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000313|EMBL:OLP93536.1};
KW Hydrolase {ECO:0000313|EMBL:OLP93536.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000186817};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1692..1709
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1729..1750
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1756..1775
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1782..1807
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1827..1844
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1992..2011
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2023..2043
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2082..2103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..89
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
FT DOMAIN 2220..2275
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
FT REPEAT 2784..2809
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 151..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 690..721
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 729..748
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 948..975
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1492..1530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1646..1671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..707
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1497..1511
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1512..1530
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2888 AA; 316698 MW; 124E229678B9B9BB CRC64;
MTSEADGATT CPTDATQDVR AAADLSAHGV CCSAIGATRS GLTVACVRDG AGWSLEAGAL
SLADGGVCCI DEFRHLAAEE KAALYEMVKW WQVGGSSNAD IADAADVARA VQPAEATWRA
QDDWPFFDSR LVVETSAQFV AASFRIRAGQ TDLRSPRSES KAGSRPSPED DGFQAAVPPQ
VQLPALKSSS KSVARKTTTR DFRLRHAACC HAHHFVGFER LATELVPRSR HLRDQLRQTL
WSLCVVPGNL KSVAEVDREQ LDELIESEVE RYLRSRLVVC QLTDVMTQDL IAKYNSDSDT
EEEAGEEGGG VEGKGLFNIA TMAKNSRGSK PWKDALFGDV GGRRGPAPVH PLGAPVNFSK
NSLAKRLQMM SINSLAGKVT GAIGQAAGSV ADAARQAARN ERRQRAKEKG MRQFEHRFFR
AFTTGLGQSL FGDREDLVFR FEVAALNVLH TYQGELPLAL HSLMGWLPAH VSNSLFVVVL
GLPALVASKQ TPDKFGMLLN CVNCIANGSG RYVFVSTPSW YLPLSARIGG LGRLHEIRER
SLALCGRPVT SVQAVWPSPC EPQEVLEAVD AVWGGRQPGV RAALGLCGGV EAMGEWVLRM
TMGCEGLLIR ALEVLKTFAP TCEAAYEELA EEGKFQSVEV PASPVLARCM AELAAELVAH
RARRRRRLQA TSDLEVVKVR SAAEMAFKRG ASQTCLKRSQ TTAMQEPAPM ESKEHGTRRG
EKPNILAQLQ RGDINSDRAT EDEHSQHLRR SVLVGPSGVR LPVGVPGRMG GRIPIHDSPK
LRPDIAAPIV EDVNLDEVAP LTAATASSTK LQRTRTAPQL RHPKSFAEQL AEMAALSKRS
HQDLKRRRAR SAPAQVDMQD FDAGNVIKNT AVALALQDEL SKVLSMECSE GPLNLFWRQG
RDEGESAELI RLRFNVGALL LFAAQRSALP PGLELPLKYF AATETIGIKE ETKPPGPEPP
GTGGETSDLE KSGGGQLNTT TLADGAFAMG FSVIFHSMPS SHFARTSPLG AGAFHVGLPH
AMLEALSDVL TQRCVGPLGE NFTVWTNGSL IVLLSAYLLQ EEHVASRHWT RLSGWLQQQH
SLFFSSSCCL RVLLAFELLM HYYAKRPDDK LVRLKEVLPF LSRVMSKVKD LPAKLDMCAD
YCQRPLLHAP KIASEMPGSP KFEPHFAEWG KEFVAGGLAV EMGVPLMDFA KWVGNLKPGR
IVYSSPNACP HWDLLLRLNW SVVILSFVVS KHDEISPEQL FRRYRRSVGE KSWWGKRVRT
ISYILIGDRL GFELENLFAS TSQKCVEIPG GCAVPGGTGD PGAPAGTRRK VDSLLDDAVD
DEMEDEEEEE EMPEVDHTVT ANPDLLCIEE TEKCDFMVRP DTEILLCKAP DCLERLLGPM
AGAVLGHRAS FDREISQEVS GDLQREVARR RAELNRARWS QDKGKLAVRQ PLPTASDKQL
TFNAEALRSI LDHIGAHTSK MLHMAEEIGS DSEDNSALGS CVSSVVPLPA LGPIKVPDSG
DRDKGEADDT SESRSSSSLS SQTASSLSQQ SQSLLLNPAL ALGQRRRSSV AEEQEEVDIE
ENPPARRRAS LHWAELRQSA KIMLMASRIR KVSRIAAAFA VPKTVPEEVI PDVDLETDAR
AGEEQGSAGI ASFPVEDAAE VATAVHFSED TQEPQRTEKR QQWRPPTPHP IQSAEGYTTW
KFGHEVSGKE KVAASMVLSA WSTFSTWWAD TTDRVVLSSP FMRRKQLRWM LSILNIWILF
DFSLGVHWHL GRTVLLTAWA LQFCIALVSL LGVLAPECFQ RYVVAVEIGT AACFSVMFVH
LCLSSLVNFY TGISWQQYTV AMMVLKMHPA AIVTTSLGYL YIWARPKTIK LEFYGPLDSC
VRRLLLFDIF QMLISAWYCV DFTNNVIAVR DGTMFDNELV DVTGDANGLL SSSRSFPCWR
RAFHWYRRSV HAAFTSSSIW QRHPFFPWVC AATILGNHLV ILELVFESVD PSAQWRIGPD
PKMCTKGQLI HYYSLLLLGT LLLSFVLTLI FRGLSRHVLS RDLHLAALIM MPCFMNIVLL
NFPRSYACPY SQMELDRLAT PTLHLAMLQA IFVMTLSKIH SVVAIGTSFV LATVTASYAG
AVVRGYSGDS VFLFVIVGFQ ILVHIADHWD SVSAVWASLE RTQANAAGVL RCREWQRDTS
VDVELRSFRD PLAAARRTNP ALQRAFQESL EAPRQRVLKF DWLGWDEPKK LFETDLRAGA
MEQQTISVAK PGLTCRLRAR CSVVAAQSWA VDPDGASLIQ LTGLPAPLLS RFDLILGLRG
ARTGDEELAE AILGAGDPAA EGQALRFQTL KDFVAAAQES VLRDSPDDNA RTLLETYYQK
LRGPGLGRSG EVSVTARSLE SLIRLSRAHA RLMRRHGAVQ LQDAVAVVFL HQVCWRSHSP
DSSQVLLSES SFGPLCPAHI RRLDMSSDIT SGTDYEVVEG AVLWSLGLEK APFVSQRNSC
PCLLPWPPLA VPHLHNIIMD NKEVQIGDPS PSDVQAAAGA LAAHAEQTAE ESDDYLQAAQ
TLARHLAAEP DASDLVAAAL LRQALGTEVV NPDTDLNAVS AALATHMAEA CSSPEHLETV
AAALAQHLLK QEVEVPVEGL ADVVAKALLT YAAMHCAGDQ PEETGFSMEG EATPARITSD
PARLLRIHAA LRQELMQGIR IGDTVQIRSA LNRGASLSAH YYSTRMPARP SVPLHGTPKG
PTTSLVNPVD WAVLEGRYKE AMFLLELTDG HMVFNRDEER SCLQVVQMAQ RSKQAVVVAS
QRGQASLLQM LLERSADVAQ QNLWGETALH VAARAGQEEV VSLLLQHGAW QKEPRKREVL
THAEAQRMQQ VIVAAGVSAD YTESILDRQL PGYQEVLQAL SETTCKADHD FTVSAILDLA
GASRARHI
//
