ID A0A1Q9DHM5_SYMMI Unreviewed; 743 AA.
AC A0A1Q9DHM5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Sodium channel protein type 11 subunit alpha {ECO:0000313|EMBL:OLP94682.1};
GN Name=Scn11a {ECO:0000313|EMBL:OLP94682.1};
GN ORFNames=AK812_SmicGene23289 {ECO:0000313|EMBL:OLP94682.1};
OS Symbiodinium microadriaticum (Dinoflagellate) (Zooxanthella
OS microadriatica).
OC Eukaryota; Sar; Alveolata; Dinophyceae; Suessiales; Symbiodiniaceae;
OC Symbiodinium.
OX NCBI_TaxID=2951 {ECO:0000313|EMBL:OLP94682.1, ECO:0000313|Proteomes:UP000186817};
RN [1] {ECO:0000313|EMBL:OLP94682.1, ECO:0000313|Proteomes:UP000186817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP2467 {ECO:0000313|EMBL:OLP94682.1,
RC ECO:0000313|Proteomes:UP000186817};
RA Aranda M., Li Y., Liew Y.J., Baumgarten S., Simakov O., Wilson M., Piel J.,
RA Ashoor H., Bougouffa S., Bajic V.B., Ryu T., Ravasi T., Bayer T.,
RA Micklem G., Kim H., Bhak J., Lajeunesse T.C., Voolstra C.R.;
RT "Genome analysis of coral dinoflagellate symbionts highlights evolutionary
RT adaptations to a symbiotic lifestyle.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLP94682.1}.
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DR EMBL; LSRX01000533; OLP94682.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q9DHM5; -.
DR OrthoDB; 339700at2759; -.
DR Proteomes; UP000186817; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0005261; F:monoatomic cation channel activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR043203; VGCC_Ca_Na.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR10037:SF62; SODIUM CHANNEL PROTEIN 60E; 1.
DR PANTHER; PTHR10037; VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000313|EMBL:OLP94682.1};
KW Ion transport {ECO:0000313|EMBL:OLP94682.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186817};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000313|EMBL:OLP94682.1}.
FT TRANSMEM 212..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 435..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 478..513
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 39..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 677..743
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 677..696
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 727..743
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 743 AA; 82777 MW; CFA00B5F29CE3636 CRC64;
MLLQGAVRDM LEVPGGGGSW AIFRTTEFRQ EVTKVTFPDA MPPHELGKQS ADATAADSVE
QAQQASALPA ESQTKISAAK ASSDVSSECS LEFKRLLQLL AAQHVQDMAS LRSELVNPGL
DAPKEPPSLN LSRSASIGSS PPEVPLPRVA REPSKDTNRM PRLSVMPQPS ARRFDPNSPH
SMRDRSREGI EQVSALERCA DFLQSAVFES ALSALLVANV FFMALEMQFL GMVSGWEIDK
YDEPVPSQSS WPTINRVITV GDFVFTVIFA VDVTVRIVVL RCRFWRAVMN WIDAIVVATS
SVQWFMPSLA IDAVYLRLIR LGKLARAFRM VTMSRSLDSL QLLLKCCASS VDMLFWSFCL
LTFIQCISGM ILSALVREYL NDDTKPLQIR QQVWDYYGTF TRTFLTMFEI LFANWGPPCR
VLVDYVDEAF SLFFLVYRCM IGYAVLNVVN AVFVQQTLLM AANDEDLAFK QKQKDWALYT
KKVQRLFSAM DTSEDGMVTL DEFAQLIESP KLRFWMSQLE LDYHDLLGLF EMLDDGDGEI
SMKEFIENAQ KLKGPAKAID LHRLETKLEL LLAQVLANTS SAAAGRSHRS STYSLQTLFS
AAGLSRESHG FASRMAAAAA ATALGDDDKS AKNVKRSASR VTLPCGRWCI TVCAEDREVA
QKLRPESTVM AYTRDSKNSA AESIAEGIQQ QVQSSDTAAE EEEEEEENGP QALLRPTTPF
PPSISEQLRC RHRRSPRGVR EGE
//
