ID A0A1Q9DLT5_SYMMI Unreviewed; 1125 AA.
AC A0A1Q9DLT5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 22-FEB-2023, entry version 12.
DE SubName: Full=Patched domain-containing protein 3 {ECO:0000313|EMBL:OLP96125.1};
GN Name=Ptchd3 {ECO:0000313|EMBL:OLP96125.1};
GN ORFNames=AK812_SmicGene21675 {ECO:0000313|EMBL:OLP96125.1};
OS Symbiodinium microadriaticum (Dinoflagellate) (Zooxanthella
OS microadriatica).
OC Eukaryota; Sar; Alveolata; Dinophyceae; Suessiales; Symbiodiniaceae;
OC Symbiodinium.
OX NCBI_TaxID=2951 {ECO:0000313|EMBL:OLP96125.1, ECO:0000313|Proteomes:UP000186817};
RN [1] {ECO:0000313|EMBL:OLP96125.1, ECO:0000313|Proteomes:UP000186817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP2467 {ECO:0000313|EMBL:OLP96125.1,
RC ECO:0000313|Proteomes:UP000186817};
RA Aranda M., Li Y., Liew Y.J., Baumgarten S., Simakov O., Wilson M., Piel J.,
RA Ashoor H., Bougouffa S., Bajic V.B., Ryu T., Ravasi T., Bayer T.,
RA Micklem G., Kim H., Bhak J., Lajeunesse T.C., Voolstra C.R.;
RT "Genome analysis of coral dinoflagellate symbionts highlights evolutionary
RT adaptations to a symbiotic lifestyle.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLP96125.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LSRX01000479; OLP96125.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q9DLT5; -.
DR OrthoDB; 3027485at2759; -.
DR Proteomes; UP000186817; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR PANTHER; PTHR10796:SF92; PATCHED-RELATED, ISOFORM A; 1.
DR Pfam; PF02460; Patched; 1.
DR Pfam; PF12349; Sterol-sensing; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50156; SSD; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186817};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 439..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 517..540
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 597..616
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 834..852
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 858..880
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 887..907
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 927..948
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 960..980
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 444..521
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 525..550
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 1025..1050
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1031..1049
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1125 AA; 123439 MW; 6C4B22D546B63847 CRC64;
MPRVKSLVCS VLFVVACGGG FSFLTNETRP EKQWVPAGSL ALDHNEYVQQ TFPSNSRFNL
FTATCNDVEE ADCNIFDPKY IKRFHQINER IMNISIDGDE IVADLDKAHK RGEGDRRPWL
QYQGQWSFMG SPENVNGSVV FNGRKCFSFG PFCGKQSILD VFKDDDYIIR TLTAEGARMA
INEWEDQENF CPLTIAVDNS PCFNSNCQKY DTVQERNDCR TLARSYCATS CPDPRNMDTC
KDRGCLTLGS FEAVEAENQL NTDPNETGQA PESAFEFQPT KIKTMVGGLV LDDTQQYVGG
KHLSGFFALN KAELFCPSQG TADPVADEWE RRALCLMGVD ADPRAEPKLE CPEDDLLKFN
GCLAEFGNAI RGDIAKLTSS YAVIIVYCAI MIGKCDAIHS GVAMSFVAVL LAPASPLRRM
GVDADPRAEP KLECPEDDLL KFNGCLAVLI VGLTIASTLG LMGYFGVPNG NLNNNLYFLL
LGLGVDDAFV LSSEYARHSQ ENKDLSIPDR IAATARTGGI SAPWFCTYAG VSIVLCYTYQ
LTVFLPCLAL NARRVEANRI DCCRSGCCCC CLPRQAFQGG VLKRGLKGFM ERVTTPMGQI
ITIVLFAALT AGGIFGTTKI YKDFKLEWFI PDSSYVNQFF DVNNMYFATG TPITINMRAS
PDAFEVQEGL HELYGYLNTT ELINHDVGVD SWYQEFMEWA VDPNQAATAS ATFTPSRTAA
IARFADRPAF YGALHTWYRG TTGSRYRGSL IWASEACNVD GSVEVIPPGC DVSGGLRASR
FNAELSLAAT DKGTNRYTTM ESMRKKVDEL VSGAFPYSFD FLYWEEVGVI DTELVRNLMV
CGGVILVVIF TLVPSPRIAI WVVLCVALSI VDTLGFMYFW DVTISGVSTI YVLICVGLAV
DYAAHIAHMF KESTGSPRER AIAAAERIGP CTFNAVLSTL LAVVVVGFSE SYVFRIFFKV
LFLVVTIAEA HGLWLLPAIL SICGGSKDPV GFSAGARPAR EKGLVLFCDC LPQNGPVDKV
NEELRELQSP PKQEEGSSSD SSAVPHSGIG QSVWENAPIG KYRAEYGNEG RFCLDHLLAL
TWMQRMSLAF AASSMIRLGT RAVTGALEDD VAGVVCVIAN SSRRV
//
