ID A0A1Q9DSS8_SYMMI Unreviewed; 2020 AA.
AC A0A1Q9DSS8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000256|RuleBase:RU363031};
DE EC=2.7.7.6 {ECO:0000256|RuleBase:RU363031};
GN Name=rpoB {ECO:0000313|EMBL:OLP98229.1};
GN ORFNames=AK812_SmicGene19361 {ECO:0000313|EMBL:OLP98229.1};
OS Symbiodinium microadriaticum (Dinoflagellate) (Zooxanthella
OS microadriatica).
OC Eukaryota; Sar; Alveolata; Dinophyceae; Suessiales; Symbiodiniaceae;
OC Symbiodinium.
OX NCBI_TaxID=2951 {ECO:0000313|EMBL:OLP98229.1, ECO:0000313|Proteomes:UP000186817};
RN [1] {ECO:0000313|EMBL:OLP98229.1, ECO:0000313|Proteomes:UP000186817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP2467 {ECO:0000313|EMBL:OLP98229.1,
RC ECO:0000313|Proteomes:UP000186817};
RA Aranda M., Li Y., Liew Y.J., Baumgarten S., Simakov O., Wilson M., Piel J.,
RA Ashoor H., Bougouffa S., Bajic V.B., Ryu T., Ravasi T., Bayer T.,
RA Micklem G., Kim H., Bhak J., Lajeunesse T.C., Voolstra C.R.;
RT "Genome analysis of coral dinoflagellate symbionts highlights evolutionary
RT adaptations to a symbiotic lifestyle.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC {ECO:0000256|RuleBase:RU363031}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550,
CC ECO:0000256|RuleBase:RU363031};
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000256|ARBA:ARBA00006835, ECO:0000256|RuleBase:RU363031}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLP98229.1}.
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DR EMBL; LSRX01000404; OLP98229.1; -; Genomic_DNA.
DR OrthoDB; 804274at2759; -.
DR Proteomes; UP000186817; Unassembled WGS sequence.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0032549; F:ribonucleoside binding; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.90.1100.10; -; 2.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 2.40.270.10; DNA-directed RNA polymerase, subunit 2, domain 6; 2.
DR Gene3D; 3.90.1800.10; RNA polymerase alpha subunit dimerisation domain; 1.
DR InterPro; IPR010441; CH_2.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR015712; DNA-dir_RNA_pol_su2.
DR InterPro; IPR007120; DNA-dir_RNAP_su2_dom.
DR InterPro; IPR037033; DNA-dir_RNAP_su2_hyb_sf.
DR InterPro; IPR007121; RNA_pol_bsu_CS.
DR InterPro; IPR007642; RNA_pol_Rpb2_2.
DR InterPro; IPR007645; RNA_pol_Rpb2_3.
DR InterPro; IPR007641; RNA_pol_Rpb2_7.
DR PANTHER; PTHR20856; DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2; 1.
DR PANTHER; PTHR20856:SF7; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2; 1.
DR Pfam; PF06294; CH_2; 1.
DR Pfam; PF04561; RNA_pol_Rpb2_2; 1.
DR Pfam; PF04565; RNA_pol_Rpb2_3; 1.
DR Pfam; PF00562; RNA_pol_Rpb2_6; 1.
DR Pfam; PF04560; RNA_pol_Rpb2_7; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS01166; RNA_POL_BETA; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU363031};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|RuleBase:RU363031};
KW Reference proteome {ECO:0000313|Proteomes:UP000186817};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU363031};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363031}.
FT DOMAIN 1525..1629
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 806..826
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1187..1211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1187..1207
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2020 AA; 221969 MW; EBBB32C337424658 CRC64;
MYSSFFAVGA EQFQLFALAL LSSTAVHVPT VRALGLSGIR DPEAITDRLT YLLSASSPPG
ALRKLREIFR LVGSHDVRLC LRARGWLPKL LSETATLWKQ ASCLSAESNL SKAADFWRGG
IWYSLSADCG AACDILEGAL EDILFSAEDH HFALQRDLLF QTKLETASPR GGLLKRRRSG
QMVVGATTKS DDDNTAVEMV VQRIRESFEA SEASLEALKE QGEEAPQEEL CTSRVLCGAS
ASPHLVRGTW YDKTGTPETQ ATESMPPSQP GLHLLQAHRD SFKHFLQDLF SFELGKMARR
VQLSEDSIVF ISQREAELRG IAVAGRNQSA SELVGVRLSN LLPTAFHGQR FSSQLLADRV
HFLQSSTSAE VAEMKGETYL ATAFVPMQVT DCETGLVFTV QVKIGSFPML TEYANLVISG
NPYVIAHRLE RSSGAYFSID TTVKGESVHT IELVTEEYSR IRCRCMLAPK EEDKLSLEVL
MPKSNVPLPA CLVLLAMGLK PEEIKGARNA ASIWKEEHLL EGDPDHDASW LAADELCFIL
GLEADKLFEG NPVAAFSFKT AWSFASRVGP LGRRRLNERL GLDVSEQHLT PKDFLATFDL
LVDSFLGKDS LQVDDIDSLV NKKLRPVGQK MQSLVRDWLS QVGEAAEGLP IKMDAVQGTG
AVCAEQEGVR ELDKFCISQL WKENNRQLFD CVNPLSEVVQ ARRITQVSEM GLDKIKRIQG
IRLIHPSHYG RICPIETGEG MSAGIVMAMA SNTRITSDGE LEAPHQPVSQ GVQHLSQPWE
YLLAQDQFGH RVAQFDVAHA ADGTLLAPQR PERGGPRASA TATPDTLKRP ESVTMTHLGL
FGSCSPAQVE YVACGAPISV AVGLIPFVEH DDANRALMGA KHQQQAVPTL WPERPVVGSG
MEAQVATYSA RTTFAGIDGH VLYCDAAKVV TVSCAGIVQV SEQVQNMRQS LRAQYFEREQ
LSQWIRFDDF CELCARLPYA QLQQLYNDVT DSQTPNDQKI KQRWQDWSVR AGINPSRGSF
MHSEGAREEA PLPAGWVETE YCIHTQMMHH LMTDCASTKK HTLAHDTVTV RASDAVCSGD
IIAEGQGVAG GELALGKNLV VAYMPYEGYN YEDAIVISER CVREDILTSV HIEELTLELD
EDLVLRNPEQ HEEDRHSDYS EYMSNGMARE GAWLQGGDIA ICSMRPNSMN DANTGGEQPN
TGEQPRPRRR TITVPDGVQG RVIDASVWYT ESVKFGVVKK VQVAKVLLAV FCRIQVGDKL
SGRHGNKGIV SKIVPVQDMP YLPDGTPVDV CLNPLGVPSR MNVGQIFENI LGSAGRWNGE
EYRVGSFDEM FAEEASRGLV FEAMRRAQIG SGNKWLLDAA SPGKTRSRGG GLRLGEMEVS
ALIGHGAGAT LQELLTVKSD DLQGNDIALP KGATSEGYLA FSRELAASGL VLSEGDADLL
PGCLEGGSAT VAVGDVSLLV LRRLLSSLSS PSPRGALLGM TRRRLVGSLV DLLRTFTVFQ
VGFSLGLWSD SVLIETPTAF AMACAPLPRE IIKWLQSLDL SFSIKNPKRD LSNGYIVAEI
LSRYHPQDVD MNTYENGSRL EAKVDNWEQL YKFFKRKGIG ISKAEFDPVI HCAPGAAVML
MYKIYTFLTK CVVDIVAIEH WSQSHFDTLE QSPWNVAVNR VSDASEPAIA KMALVIMRQL
ELRGVPIINP SSAYSLLMSK SGQYAVLQLA GVEMPESTFV NGLGRTANSS QALSGLTQPQ
DKFPLLYKPC AAAYAKGVVT MKDEAELEAF ASQVQSFANS PSFEVSPLGN DYTGFLQKFC
APDLGQYFRV FVLDGKFQCA IKVVPRDESG PGATVTSTCA CSANKTSSSP LRFFAYTPTE
EEATEAVRIL SEVAQADCGS VEFLRIEGRR LYFDVNLLSH LPVRDESSDT FPGFEDPEGL
WSNRNFYAEL AMVQAHAPIQ ELVNNQHELP SFMRDTASKR LKDPEISRIQ DNVERTIIAI
DTLGVFHQER RAIKATEAPA LIRQERRLRM GLSQTATSQS
//
