ID A0A1Q9DWC9_SYMMI Unreviewed; 646 AA.
AC A0A1Q9DWC9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Multiple C2 and transmembrane domain-containing protein 1 {ECO:0000313|EMBL:OLP99485.1};
GN Name=MCTP1 {ECO:0000313|EMBL:OLP99485.1};
GN ORFNames=AK812_SmicGene17949 {ECO:0000313|EMBL:OLP99485.1};
OS Symbiodinium microadriaticum (Dinoflagellate) (Zooxanthella
OS microadriatica).
OC Eukaryota; Sar; Alveolata; Dinophyceae; Suessiales; Symbiodiniaceae;
OC Symbiodinium.
OX NCBI_TaxID=2951 {ECO:0000313|EMBL:OLP99485.1, ECO:0000313|Proteomes:UP000186817};
RN [1] {ECO:0000313|EMBL:OLP99485.1, ECO:0000313|Proteomes:UP000186817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP2467 {ECO:0000313|EMBL:OLP99485.1,
RC ECO:0000313|Proteomes:UP000186817};
RA Aranda M., Li Y., Liew Y.J., Baumgarten S., Simakov O., Wilson M., Piel J.,
RA Ashoor H., Bougouffa S., Bajic V.B., Ryu T., Ravasi T., Bayer T.,
RA Micklem G., Kim H., Bhak J., Lajeunesse T.C., Voolstra C.R.;
RT "Genome analysis of coral dinoflagellate symbionts highlights evolutionary
RT adaptations to a symbiotic lifestyle.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLP99485.1}.
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DR EMBL; LSRX01000360; OLP99485.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q9DWC9; -.
DR OrthoDB; 5385125at2759; -.
DR Proteomes; UP000186817; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00030; C2; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR39490; ARRESTIN DOMAIN-CONTAINING PROTEIN D; 1.
DR PANTHER; PTHR39490:SF12; FYVE ZINC FINGER FAMILY PROTEIN; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF01363; FYVE; 1.
DR SMART; SM00239; C2; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000186817};
KW Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:OLP99485.1};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 569..594
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 129..191
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 221..343
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 94..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 627..646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 646 AA; 70826 MW; E83FC9FD82EBD849 CRC64;
MLEISIAVVD VVMIIMGIAS IGKSMTISWT TKIIIIIIIS VIFYLVVVTN LITSINLYRT
SGAKSSGPHD SGVQAIRVRN GSYQIDSGAA RAWPSPGSAR NMAGEPLQPV PSRKTSSMSS
TSTVEWVDNS AADACMSCHA RFGVMQLRRK HHCRRCGQVV CRACSSAREI VPEYHPIKPQ
RVCVACVSNR AETQESEEAA ESVVTAVRSG KRGTRPVRVN ALGGMALPSY DDKKHEFGTL
RVRIIEAKGL LAADYGLMNK SSDPYCLVNA GHSVQVRTHT VSATLEPRWD TTLSFRLSRP
DDVLHLEVWD EDTTSRDDAI GFLDLPLSQV PLSSSSAPLR GWVPLCRPEA QALPGEVVNL
PAKGAGAVLL EVQLVDVEQF KLFKAFAAPL PAVPQPPPPF DVDAVYGPAM HLVDLLWTRF
FSPILFWLLD LIFWASPIRS LVALILWNLG ARYGLPHYPA LPPLGLLSLS CRKWEAVHPQ
PPLSRQDSAL AKDYDEAQLG SAVQRLCFVL PSSIKDLCRG LQPLLRTVAD GLQMVHDIFE
WEHSASPAVA IVLILCTVVS EVLRFDILLM LIGSAVLLVC SPLVPAVSGT IGFLSYRTAQ
GRPKVWGMQD EYNEEWSSKD YRDITATTSA QDSPQRPRLR HAFTKA
//
