ID   A0A1Q9E110_SYMMI        Unreviewed;       533 AA.
AC   A0A1Q9E110;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4D {ECO:0000313|EMBL:OLQ01124.1};
GN   Name=Pde4d {ECO:0000313|EMBL:OLQ01124.1};
GN   ORFNames=AK812_SmicGene16156 {ECO:0000313|EMBL:OLQ01124.1};
OS   Symbiodinium microadriaticum (Dinoflagellate) (Zooxanthella
OS   microadriatica).
OC   Eukaryota; Sar; Alveolata; Dinophyceae; Suessiales; Symbiodiniaceae;
OC   Symbiodinium.
OX   NCBI_TaxID=2951 {ECO:0000313|EMBL:OLQ01124.1, ECO:0000313|Proteomes:UP000186817};
RN   [1] {ECO:0000313|EMBL:OLQ01124.1, ECO:0000313|Proteomes:UP000186817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCMP2467 {ECO:0000313|EMBL:OLQ01124.1,
RC   ECO:0000313|Proteomes:UP000186817};
RA   Aranda M., Li Y., Liew Y.J., Baumgarten S., Simakov O., Wilson M., Piel J.,
RA   Ashoor H., Bougouffa S., Bajic V.B., Ryu T., Ravasi T., Bayer T.,
RA   Micklem G., Kim H., Bhak J., Lajeunesse T.C., Voolstra C.R.;
RT   "Genome analysis of coral dinoflagellate symbionts highlights evolutionary
RT   adaptations to a symbiotic lifestyle.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OLQ01124.1}.
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DR   EMBL; LSRX01000304; OLQ01124.1; -; Genomic_DNA.
DR   OrthoDB; 199121at2759; -.
DR   Proteomes; UP000186817; Unassembled WGS sequence.
DR   GO; GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.1300.10; 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain; 1.
DR   InterPro; IPR002073; PDEase_catalytic_dom.
DR   InterPro; IPR036971; PDEase_catalytic_dom_sf.
DR   PANTHER; PTHR11347:SF198; CAMP-SPECIFIC 3',5'-CAMP PHOSPHODIESTERASE 4; 1.
DR   PANTHER; PTHR11347; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; 1.
DR   Pfam; PF00233; PDEase_I; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   PROSITE; PS51845; PDEASE_I_2; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000186817}.
FT   DOMAIN          291..506
FT                   /note="PDEase"
FT                   /evidence="ECO:0000259|PROSITE:PS51845"
SQ   SEQUENCE   533 AA;  59224 MW;  51627D759736D5FD CRC64;
     MLARSLRASL SGASPNDGSG VTSAGSKAQS RILDTTWMVL SIIPGAEFQA VCGYHFATND
     GALISSVVLH LSDDEARISV SPPAVTEKSV GLLHETAFAS VTCCGFELTS KRECLKVLKE
     GQSATEEPFP GYKFFLLLNV CKNQCREIDA SQDFPWSFLD EGVKQTLEVN LDPPRIDTYA
     AAFSNSKVPA LIRFYGRQSC VLLEMNCPML LGYELTIMTD PDLSLLTVRC SASFSYAIGP
     FAVAGLLKLL SACSESKKCG CIAWFSAPTG XPGNVLFSAL DLTFALLGSW AMTYNDRSCL
     ESMSCSRLFE IVSQPHCAIF EPLSKNHYNT VRKVVIAAIL NTDTAQHFQS VKKVQMFYEM
     NSEVLQMAGD VYREQVEEDE EEPVFPLPEV ADVFKDTNNK QILVNLLVHL ADTSNSTKPF
     RICKIWAQKA MEESFLQGDH EKALGLPIQA MNDRFKANLS FSQFGFIEYL VAPFLMTVIK
     VLPPVEPMLA QMMLNAKCWQ HAYEEEGFPS PEEREALQSR VTDLVRLYNE RWK
//