ID A0A1Q9EJ72_SYMMI Unreviewed; 2736 AA.
AC A0A1Q9EJ72;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=RNase H type-1 domain-containing protein {ECO:0000259|PROSITE:PS50879};
GN ORFNames=AK812_SmicGene9187 {ECO:0000313|EMBL:OLQ07401.1};
OS Symbiodinium microadriaticum (Dinoflagellate) (Zooxanthella
OS microadriatica).
OC Eukaryota; Sar; Alveolata; Dinophyceae; Suessiales; Symbiodiniaceae;
OC Symbiodinium.
OX NCBI_TaxID=2951 {ECO:0000313|EMBL:OLQ07401.1, ECO:0000313|Proteomes:UP000186817};
RN [1] {ECO:0000313|EMBL:OLQ07401.1, ECO:0000313|Proteomes:UP000186817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP2467 {ECO:0000313|EMBL:OLQ07401.1,
RC ECO:0000313|Proteomes:UP000186817};
RA Aranda M., Li Y., Liew Y.J., Baumgarten S., Simakov O., Wilson M., Piel J.,
RA Ashoor H., Bougouffa S., Bajic V.B., Ryu T., Ravasi T., Bayer T.,
RA Micklem G., Kim H., Bhak J., Lajeunesse T.C., Voolstra C.R.;
RT "Genome analysis of coral dinoflagellate symbionts highlights evolutionary
RT adaptations to a symbiotic lifestyle.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLQ07401.1}.
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DR EMBL; LSRX01000139; OLQ07401.1; -; Genomic_DNA.
DR OrthoDB; 2298697at2759; -.
DR Proteomes; UP000186817; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR001466; Beta-lactam-related.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR Pfam; PF00144; Beta-lactamase; 1.
DR Pfam; PF03372; Exo_endo_phos; 1.
DR Pfam; PF00075; RNase_H; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000186817}.
FT DOMAIN 1099..1255
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT REGION 269..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2395..2415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..326
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 399..413
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2736 AA; 296031 MW; 56832B89EC0E5496 CRC64;
MLWHTIMQEP DFVHPLMSTQ LAAHASYMKT SYDVEVYIRE MDPRILHYEG NSSATPGWAG
GGSSAPMFRR SDGHMDSQAV CTADVIGGAS DAGSAQSCRR NHNADVKLSC AAGAGGDRKP
GILKVSPPPG DSDLQACTDA TKVVKFAATV SNVFVAEPET GFFSEVPPPR PPTQVHKAVA
TAAPSSRLRC QADTALLGVA GPLQLGVSKV GSVSSLAHSA AAAQKQDRLQ PTDSAEVLPN
HMPSRYLGVA GPCKQTSIKL QAETGYPQIG SVPPSVPPAL HEAACPSAPG ASKVGSLSSL
ARPPTPTTPE MPMKASVLSR NPSSLLGVAG PSAPGVSKVG SLSSLARRTT APASLPGGPA
AQRKAPKTGE ALRRDPSPPL RVAGPPIPGD KENRVPQQTP PEPKAPPALL GREGPPRPND
ISKLGLNRIL FLPEHLARYP VNEIPVDQLG IYALEPGHAR RLLKYSVFDR QRHHQQRTAA
YGWSLNDLVS EAVRSSEERI KTAQVLTTTM PQLAVPQIVL TPDDTAHNQL CVPIDLRPLG
GRPCTLLLQE GTPAQDVILE ALRACPAGPL FVPPSGEARD LFLVDAQGNV WDELPPDLSQ
LQWLRIQGRR PLDMLQAASP EPQYGPTAPS HRAGTTTLTA TWVMEQQNVQ TVSFILAGLG
ITVRLHPQHI SQARVPESMA DLVMAIARQR RLPPRTRVTL VAAQPMPLQI QHIALLFIIY
PEDDRRHIIL DPSGDGSMAQ SISVDDQTRP EELLAEAQRR QGYEISVNGI PQSAMRRGIC
TGDYVQVIHN PRRHRVSPAD WYYQIYPDLR LFAFPIEFPR LQRATAMPLD ALAQTQVRDG
LLRYLQPRLE QQRGIMGQPA ADRQPVFVHG PGHAPALLYV PGRILPVLAE VEPSIHATEL
FPTGTSFVDS CQVTHMHAPL FLSVPPNLPG LGVFVPAPSF LMGYHLMWVT PDTAATVRHR
RITSATAASP RAPASGTSLV QLRAQRITAP LRSMQIATPL GRRQLKIPAE ACPQPGKNSA
EPQKALRLAA LLEPPSSQIS AETVGGDAAR KCDSQGPGVV PEIPPLSAWN VAWQSTPPGV
FKGPARRLLH DREPPGQWPP QAIHVYTDGS AGGGEIPGWA VAVFELCTNG AHYWENFLGC
SSGSCKAFAQ HAAGAAEHNI DAEAAALTVA TAWAAAWPSN VPVHIWSDCE TVVRAALGNA
DLHQEGRTAR LLQSCRHLWQ LLERREVPTQ LHWVASHQGV PGNELADQIA KHARALNTPA
LPDAFFELIK HPGLPWLWHA LRPSPALPQL AQLQHHVYEP ADPVPEHCFP LPTPAAGGRQ
TEPKALLLCT YNAQSMHKKK ELCRTQFKAR GVHIAFLQET RARTSSICTA ADYITVSSTA
KQGQGGCAIW VAASLPNCKV KANHIKVLHQ DHRILLARLC TAQLDCLLLS AHAPHSGAPA
QEREAWWEGL QSLLRKHYTG SIPLLAGIDA NAQVGAIESP AIGSHAADEE TPNGSCLREV
CDAHCLALPT TFCGPNGKTQ SVDADAYTWT APNGARYRID YIMLPQPCVA AVEARSVWHT
FETGGPEDHV PVLTSLRLRA KGDRANSLTY PRLPFKRVQD VQESSCDFIE VFSAHTPWNV
NIHEQVSCLD NLLWTEAAKA PKQRRPANKY LNDTAWQLVR ERKVAKATIR WCADRYRRLQ
LSAVFRAWKR QHRPPHLRPE ASAAGARIAE AGQQLEAAIA AHKALLPALR RGIEASKAQY
LSRLAQEYEE AASAKDAQAL YAALRYFRPA GKKVFKPFGP ATVLQDAEGH VVATHADQQE
VHRKHFQEQE AGEATTVAAY CAQPVPPTHA GNVSLQDLPT LSEVEAIIRG AADGKAPGPS
GVPSCIWKCN PAAAAHALLP IYLKSHIRLT EPVQYRGCRL VAMLKKLGQS VQAAHFRSIA
LFDASAKFYH RLHRSRLVAE LQSSNLPLLQ GCVPGSGPTA LTHLLSTRLR IARHKKEAAA
VLFLDLRAAY YRLIRQAVTG EISNDQELCL IMDRMGISPA HVEEVAKFAN SGGLLRNTSQ
HFRKVLACSF HATYFVVDGS ETITRTRIGS RPGDSISDVL FGLAVADMHK AVRASLAADG
IPDQQLPTWA DDVALPIQAA APQLLALSSH VAATLHNECQ NRGMEPNYDR GKTELLVVLH
GEGARKVKQG LFRSGQAQLS LPTAPAVSLT CVTQYKHLGT LLRATGKARQ DLRQKFAAAQ
AVTAPLAKQV FRRQTVPLAD RATLLDTLAL TRATYGVAIW HDLTQAEAEL WEQGLAHLYR
ALHKPRIVDG SPRFPDAPIL CYESGRPQAI AQRRLLQLEH LRAIGAQGQE ALLLALQEEA
ALSTQSWLSE AQAAVTWLAS TVGDLLAQNG VSTVEQFIEH SAAFPGQVKS WIRKGKHKAS
QHKPAPPELG PGTAPPGDAT AAFRCECCDV VCHSLHKVRA HMWGQHKHGC LLTALAPGTR
CPACLTEFWL HKRLVRHLMH DSVQCGHHVL AGGSTSATNE GPGKARDDTL PKDTLPAIST
PGPRPPCLSE WVSAEQLYRL QTFFEESGGG TADPVIAAQR SLSEYACANA ATRDAFLAWL
GPEKAPLYLR GPRAPPWRIL PEEKNRRKVE YPCPAGNGRG PAKELAALYA SLLPGAPGPL
LQAETVQQIT AVAREGIYDE LQGVDTPWSL GFAVNCILSG RHASPKAFGH GGSQSSWAFA
DPEHGLAVCC LCNGKPGPDL HYKRVGAVST AVYEAM
//
