ID A0A1Q9F1C5_SYMMI Unreviewed; 1270 AA.
AC A0A1Q9F1C5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Vacuolar amino acid transporter 1 {ECO:0000313|EMBL:OLQ13451.1};
GN Name=AVT1 {ECO:0000313|EMBL:OLQ13451.1};
GN ORFNames=AK812_SmicGene2540 {ECO:0000313|EMBL:OLQ13451.1};
OS Symbiodinium microadriaticum (Dinoflagellate) (Zooxanthella
OS microadriatica).
OC Eukaryota; Sar; Alveolata; Dinophyceae; Suessiales; Symbiodiniaceae;
OC Symbiodinium.
OX NCBI_TaxID=2951 {ECO:0000313|EMBL:OLQ13451.1, ECO:0000313|Proteomes:UP000186817};
RN [1] {ECO:0000313|EMBL:OLQ13451.1, ECO:0000313|Proteomes:UP000186817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP2467 {ECO:0000313|EMBL:OLQ13451.1,
RC ECO:0000313|Proteomes:UP000186817};
RA Aranda M., Li Y., Liew Y.J., Baumgarten S., Simakov O., Wilson M., Piel J.,
RA Ashoor H., Bougouffa S., Bajic V.B., Ryu T., Ravasi T., Bayer T.,
RA Micklem G., Kim H., Bhak J., Lajeunesse T.C., Voolstra C.R.;
RT "Genome analysis of coral dinoflagellate symbionts highlights evolutionary
RT adaptations to a symbiotic lifestyle.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLQ13451.1}.
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DR EMBL; LSRX01000028; OLQ13451.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q9F1C5; -.
DR OrthoDB; 3425278at2759; -.
DR Proteomes; UP000186817; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR013057; AA_transpt_TM.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR PANTHER; PTHR22950:SF688; AA_TRANS DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22950; AMINO ACID TRANSPORTER; 1.
DR Pfam; PF01490; Aa_trans; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186817};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 907..926
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 933..957
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 993..1018
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1056..1074
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1131..1155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1191..1218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1239..1258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 907..1266
FT /note="Amino acid transporter transmembrane"
FT /evidence="ECO:0000259|Pfam:PF01490"
FT REGION 111..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 169..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 242..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 626..648
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 727..761
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 872..895
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..139
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..304
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 878..893
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1270 AA; 137544 MW; 06E2DD16AFBBA2CA CRC64;
MEDFASKLRE RMNRTEDLTY VRSDQYILLG ELLTSPELSE AMCLAGIDDG SGVNFQKDSG
KVTLTPEINS FIEQMVENCQ LHEGEKVFDY WADTGVGSWI RLAGKRQSQG QYQYRRYSHG
SGSSHGPNGS FSGGNATRPA RQVESCPPRS AQFQARALPG WVTRVQSADG VATPATRTMP
AAASSALPEE ASLPPSSAST FLTEEVLPKA QPDRPPPLPS ENTPQNSSHV VAQAILKRNK
VSNKMKHEST GTPEIQVAAP APAPTPKPPP AELRQVAPAP PPSIPSPAQE PIRPVQPPAP
EIAPEQAKEP WELPEVSKAW LRGKLRSYHP DQACGYLAIP GRGELLLRAS AIEGDVPSEL
AEGWQIEVEV EDLEKEPRIL RAKVAAAPAL PLKESRAPAE APATKRGRIK TFMLEKGFGF
CQLEEADRTV DVFIHINSFE GPAPEDFHGM PGSPPVGQEV EIKLGDNSAR PRACWARVVG
PALPIDKANA LSSCLSHVLK SAERLLEGKP KKGGWHKLVD ILATDSLRVA VTAYSPNGVA
EIKMGIVPEP LMNCLHDLAV CVVAPTPEAA AEAIAGSVPS TAEASESSSR FHLWLEQEAF
ISENTTPEAE RLWIRAAHRG GARGVLAAKA QPEKSKQGKE KSWWEGGGTT ARTGLWEPQH
LKALCSNPLG DCTADDVLKV LGALPVDAPS EVRRYLEVVD APPAACSKPG ELLAAQVAQC
ILNAKDDSPG DSRDKAAVET KGTRAVGSCT PSAPSVASGS RVRGHPLTQE VISFSTNVLR
GNLSQEEFNK KLTHLQIQDK RIGPDLEGLR LVPGVYVLYA YDNVISSLAG IENLRRLQQL
FLQNNRIASM AGLEVFVLEE LILSCFGPAM RVPDEPSSEE EWSEEESGTV QPWDSDDELD
FTPGMPWWQA TFSLVVVVIG VGVMALPQLP VKGGWWMSIL SMLVCFMAIA ESGIAMWKGV
MAGNHAGAKD LAPKAIVSYE DFGKAAFGKT GEALVLLMMM LYFLGVVASF GVLIAEELEN
LIGHLSKKEW LLAFAPVMIL MSQLPNVTAV AKMTPLAVLC ILILVSVIIS KSVLDAQRWQ
AWPDPAKLHT DWPEDPMAMG TVVATMFGAF GVNGNVPSIL CEMKDPMEFP FAYKTAMTIV
LLIYLAVMCC GYYGYGDFMQ PDIVKSLSSF PATEEQALDV KFDDWTGPKA LILRGVCAAL
LLIKLIIGLP LNMMVIYYSL QTYEGTKDWF PAQSVANKIM RVLVAIIAIV IGLVVTQFNK
LFALVASEPF
//
