ID A0A1Q9F7K5_SYMMI Unreviewed; 5230 AA.
AC A0A1Q9F7K5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Ankyrin-2 {ECO:0000313|EMBL:OLQ15660.1};
GN Name=Ank2 {ECO:0000313|EMBL:OLQ15660.1};
GN ORFNames=AK812_SmicGene131 {ECO:0000313|EMBL:OLQ15660.1};
OS Symbiodinium microadriaticum (Dinoflagellate) (Zooxanthella
OS microadriatica).
OC Eukaryota; Sar; Alveolata; Dinophyceae; Suessiales; Symbiodiniaceae;
OC Symbiodinium.
OX NCBI_TaxID=2951 {ECO:0000313|EMBL:OLQ15660.1, ECO:0000313|Proteomes:UP000186817};
RN [1] {ECO:0000313|EMBL:OLQ15660.1, ECO:0000313|Proteomes:UP000186817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP2467 {ECO:0000313|EMBL:OLQ15660.1,
RC ECO:0000313|Proteomes:UP000186817};
RA Aranda M., Li Y., Liew Y.J., Baumgarten S., Simakov O., Wilson M., Piel J.,
RA Ashoor H., Bougouffa S., Bajic V.B., Ryu T., Ravasi T., Bayer T.,
RA Micklem G., Kim H., Bhak J., Lajeunesse T.C., Voolstra C.R.;
RT "Genome analysis of coral dinoflagellate symbionts highlights evolutionary
RT adaptations to a symbiotic lifestyle.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLQ15660.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LSRX01000001; OLQ15660.1; -; Genomic_DNA.
DR OrthoDB; 207309at2759; -.
DR Proteomes; UP000186817; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06257; DnaJ; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 1.10.287.110; DnaJ domain; 1.
DR Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR036869; J_dom_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR013103; RVT_2.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR24123:SF33; ANKYRIN 2, ISOFORM U; 1.
DR PANTHER; PTHR24123; ANKYRIN REPEAT-CONTAINING; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 4.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF07727; RVT_2; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00248; ANK; 11.
DR SMART; SM00271; DnaJ; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR SUPFAM; SSF46565; Chaperone J-domain; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 9.
DR PROSITE; PS50088; ANK_REPEAT; 10.
DR PROSITE; PS50076; DNAJ_2; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000186817};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT REPEAT 435..467
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 468..500
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 501..533
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 534..566
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 594..626
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 628..660
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 662..694
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 729..761
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 762..794
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 795..827
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 1906..1945
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 2210..2288
FT /note="J"
FT /evidence="ECO:0000259|PROSITE:PS50076"
FT REGION 21..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1999..2018
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2173..2207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2346..2367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2608..2672
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2794..2836
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2943..2979
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2992..3030
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3558..3597
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3861..3880
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3889..3908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4350..4383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4432..4467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..92
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2183..2204
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2997..3016
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3575..3589
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4350..4365
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4450..4467
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5230 AA; 574432 MW; EEC129A7961003CE CRC64;
MSATPRFPYN SAQVFSYQVA TRPRSAPFRR ATRPSSQRAA LWRTTPTRRQ RAEKAPKAAI
SRSANVDSES EEEPPETHAA GQGEKVETRA ARSWHIPDLQ IRELVKGWEA EAATPEPVLP
RAATASPSAS QVNRPLLACA RRKRMPETPQ RPMTCEPLVS EEPILDEEAE EKARAEFEDA
ERQRIKYYFR DAHAATEQQP TVTEAELQRC ASAPTGPAGA AKKRPALPRR NGELKQLERE
AKAAKEDTRL TLNFVDTGDR YVVRVDPDLP IGPVPGQTGG DKPPSLKEII EDISGIAPSQ
QILFCHRAKM GHDKYTLRSY HAHQHAQGLG PLCCYTPVHV ANVRISLSIA GTTRFYQYRT
LQKQPSHVGK RHVAARTTGL RKATLGAPTA CSRIIAGTAL CRIAADAQAA LAQAVRRGNV
EEVRRLLAAA SSLAQSPGLL HMAVNVGELE VVRALLTYGA PTETSSSTGA TALHVAATKG
EDKLLLVLLE ASAQVDACTM KQQTPLMMAA RVGSVAVVQA LLDHGASAER CSADGETVLH
MASGASTDSV LRLLLDRGIS LDARTRTGCL AGNLPGLRLL LARHGDLEAR ATNEGATALH
TAARKGHAEV VRELIHAGAD LEAATTANGY TPLHFTAFTG SSAACSVLLE AKARVDAQVG
ISGETALHLA SMSGHAGVAK HLLAAGATKD AENASGLTPL LMAIMYDQSG TVTPCLLEAS
ANVHATWRLG STALHEAAQR ADATTVAKLL DLKAAVDVQD THGDRPLHSA AAGGHVETSR
VLLERRAAMD AANAFGLTPL HAAAFNDCGD VLSLLLDLGS QAATAEDQFK ETPADVACSE
PAIRRLLLAQ GLSGGTLDGR VEECLASLQR ERAQHCPALD ARALGLSAAW ADAADATLTP
LERRLLVLRD IEKVSPGALI RELARVRRSA TFDRRVRSLL VDSDAAVLQK AAVLPAEACQ
TLCQEVDQKA SLRGGRTDSM PEFTLHLSRG ELEGLIGKGL VASLFATAAA YRKERGLLGP
DKEMEIFLRK YSASTRPWIK MHADIATVTA NVALSDEEGV GGQLLGFVGG RIHPMQRRAG
DVTVHSSSLL HGVTRMASGI YVRFAKGTVE TPSILHACTA KWRQQQAIRN NRRDRARACS
ETNSKHHVMP DWQKCVVPAN GTFFQYARRG IEGKLAQCFD LHHVEKTAGI RVQKLTGLPV
VLAVCVVAEE AGCSSMALGF HALEPQIAEW SWAWWRLVEP ALVLQPLDPQ RPGDPVEVGS
SLETGHSSGI AVATGPSEEQ MIEQLAADQN ETRGDDVALA AQQALFEAEE DTYYRGVEEV
VSGELEAQAA RAARSWDDWA LHDEMYQASP KPRKRPCIEI MVSGGAGDDA QGSERRWKVP
FAARGGRVVL SFGYMEMGEA APSETSTDPV HVDPVTGAGV RQEKAAGTEH LSTTIGDGHG
LEGAIPMDFP AFQELYEGWV RGDVSDAAVA EQHGQATLEL LQAQRIVVSS DLPGATPGDR
THLFHDPFAS FGDYHTWRPE HGVAEWDRLR SGPAYSHKID YPKRVENRRC IAELTPSQAM
AINASRAERR TDEYLKLSTS TSDIVAPGSY EPKLGKEVGE AVAPFMSLQD KELNPLSLMA
KMTPGPGSYA GQEPLPSTTQ EAYQILERAR WMVDGDNQGS RWEYHPLTNN CEHFVNFCWD
PQIPPRSDQV NNGLTTLAGS MTVGALGAGI PGTIVAATVT PVATAVTTTS TYYALGFIPW
GTVATTTTVM ANLPVGVVIA IGAGSVLAGA GILGGAAYGI REWSIADAAA NANMLPIAVY
NTSNQPITAS LSHDPKEGMA WALDSLYYFR SWTGVGLMSR AIDTQMAEEL NPPTWTEDGD
DQFVLTIECQ PGQPLRSISS IVSRGDVLTF DGQNCTKQDA AEPEECGICL DRRPNVLLQP
CGHWGYCEAC IQEVQRRTNT CPTCRGTIEA VDVAVLSGLM AVPYPEQVPI HEYFSGPQNY
NPELQTSYIR SMFDFDGLDA SDDDATKEES SESPAEEGPL LQARWQQLCL EPALVPRFQG
DPERVLEEME ALSTLRAKEL QRECERAGIP IAAGAEKGEL LRSLRQVFAW RYLDDESLQE
LCRSKGLADK GDPEAMRQRL FTSSFGAPAG GSRHGNIFAK ERSSAWSKED RCSYAQAHSG
DGSQAFRANL RAQGVAQRAE MPRPQPPTGP PKPRPPPVPP KPAMPTEVAS ALRQLDLPLD
AGEDQVKKAY RRLALLYHPD KNPSEESAEH FRRATKAYET CCEYLRGAGR KMPGAASAAG
RKSLSQMSFK SKLKRLAAST PGSTVYTEST IAKNPGPGTY GRKGSMTPPP MLDLMPAVKP
VLKDRDKTAP SVPPMRYLPG QVPQTEAASA DVAKLTSRHT GEPRDMAGPG EYDIVGERKL
AKNDRITVFH DPGKRKFRQL WEPTVAIDCA AAPTDLPGPG AYDGTTTAKP GNHAGAVTQF
VSKSPMAQDV EVKDKQRTPG PGAYTIVAKI DKSLSEQQER MEAVGNSAGF GSMTERVGWS
RDLNQPFKDP YHVLRRVDTT GLCRAGDEAV RAFLLAQSLH STVLPAVGSF AKRLVPELVA
CWSAAVPPEP TGWPLCGCRI GEARHPGPVA PGTPVGGERP APVTPVEAEC SGPSDSGRDA
APVVLISDSE PEVDAARAKR PRKQYQQYDS GQQSFDVQLV PGESKSKVED RVFRTYCRQW
MQKYDSELGM LSTAWRSGTD LRLKHVPGPG HYTMSPGDWK DPNEIDPNKV LQRPRRSLHG
VHHPTLILAL QETEGPLQAF NTSDDRRADR FFRSPLNARE GLPDPSYDGG KINMGKDPSS
PEARSPFQSG SPRMQAAGDA KEVGVIRLGE LQTPAPGEYE IKEPNYRSPY RMPRSEHLSF
GSGTARFHEK QEVFAKFKLP EGPSPGDYNT LPSKRHVVGG ARLKDKRKPA TVGCTTTTDL
VVGTDNGSLD NDEVQAEESD PWRSAAEARR DAMPGPDSAE FARFREFMVT RQTSGNRAWR
PRRDRSDDES ERDNGGDRSN AGPAPSWDGT TAFKDYQIRA RLWLATTRVK PKSRGPMLLK
SLAGTPFDDM KYLAKDSAWM SDPENGEKLI QLMDSKELYG EDEREDMINT LVKITYTLRR
TKGENNKAFF ARWDNIVRRL EEHKVKLPEE YLGFLLTNAL NLSNEELKLL LNFTQGRLKT
KDVKEWLRVH ETEFENKTSK LANPKANQVL LVGEAEPPDY GLDEEDLGEP DPDGIEVLLG
AIQELDEGIN HDGENENETV FDETEATEIL AAMIKEHTKG GGKRSFPAVN KAKKAKALAR
GYGSGRDAGQ RFREPPNVKV GNTYKVSIEA LKRRTRCGIC KEIGHWHREC PRNTSNNGAK
ENHFLESEEA LFLDYIEYLD FKEQSSSASS TSGKGIGAPP GLSDPSLRAA YTVPVHEVLY
VDQSEPVRED HCATVDTGCQ RTAIGAETLR KFLANQDHQV GCCYKPEAHC FKSVNGMTST
SQIACLPTSL GRKGCILRPA IFEDGQSRQA PFLLSLPFLL YCRATLTLDP KIGLSMHLGR
FNYRVPLHIG PTGALRVPLD SGSSVDDGRP HPSIRSTDTS ESISQSSEVG KEADGPREAE
LVQHLHQEAH ATEQRRRVQA VPGMAAVSGF QPAESVGIQL QGSDRIGPDR LGLPRRKLES
ELKRFEQIWS RLVECLGPDS ERALCELKQQ TVRELQRPSR KSLAFYRELF GMTDKQLRKV
AEIHNPLSAF HRAKRSEFNA GQVLDIELGD DLLSEPVRQS VMTHLQHDRP GLVIIYSSRA
RPDQLFSLSR SFVAKDHANL KKHLDSTRQG RKLLDFALQV CQRCCQLGLS FVLDCPWPPR
SWQYRWVQSL AATAGAKLSA YGPGPHRLHD PGREDRQSQQ GVFTNHPSIA KFISNNGSPE
GPKDRGGLNS LVVTPYAQAN FRDPKEINVR RYQEICDGDR RIDRAYFAEA ELHQIEHENS
PAIFPDFTKE VLHQEDEAIE IRRATFPDSY EGAAEHLDED GWHELSNGDW MHLARSTGNI
TVPEANLPAA SLPWRSTWTK NGDQGWRLHE DEVRWQDLRD QQRRLPLQDF IATVYQAKID
SAAERKMRQF PGLRQVTLEK LVRRAHEGAP PRESLTVNDL VGIDTVHLRG TNGLQAVGKI
FRASEKTHDR PRHRVYKSNF RRQAERDGTE VIPSSLEAPY QRGLTERAGG VFKNILYKAM
KDYDCQSEAE WRELVDISCM MRNRLLIRGG YSPIQRVIGY SPRLPGGLLS GGTDDHMAAD
LIKIGDAQAE KAMKMRRAAA IAFHAADCDQ ALRAAVHSGP RPHHNFENTV IKAAPERVRP
ATEEENLSLS GWMSGIAQIR KDFEAAPKRG FVDLTQERDP PEFSGDEGEP PGEPEPGLPP
VRRVRQKTGT YEFAREPEDP LPSADLSTAL AGNATSSQPM EIEDEISAGA APPEIENEDT
GMDLEGTISG SQENKRELDA APEPPGKRSR LEFLEAYNLQ LQALMKQRQR KESTAKDFKG
RDAARLQRAI QKEIRNNLET GAYRLLTLSE SEKILQNKRE KVMNSRYVLT KKPLEPSDVA
AAQADDTLLD DDGSGPHKAK CRHVMQGFSE EAAAEVESTT PQVSRDSVIF VAQVLSSMRW
IPGFLDFTQA FHSGDAIERE LYCFQPKEGI PGAHPQQLLR LMKTCYGLTD GPLAWYRHLS
RRLVQDFGYR RSLADPCVFY LQGEGDRAGT LDGIIGVATD DLLHGGNDRH WQVIDQIAAE
YKLGKNQSGA GRFTGKDIKQ QEDGSILIDQ AFYVGDKVHL IKISRGRKQQ RYSKCTPSEI
EQLRSQLGAL AWLAKETRCD LAGRVALLQQ AFPQPRVADL IEGNKIAEEA HKYATTGIRV
MPIPWDRLRV SVVTDAAWGN AKDCIWVEDN ATDWWEETEQ QWIRHHVTPR RTSFHPGAAP
DGPDLHQITG SRKTILLAAP DQDEPDQDEK TDVWFDSQGI RVLRDLPWTG STTFEKAREP
RLQVPPAKIH SSLIQLQNLA CQAGQIILYH DTDLAQSSVP AQTTVASWKS FKLRRKVVDT
LAAEGQALQS GVGAVHWHRL LFLEAFHGMM QADDWRREAC KLPFLAAIDS KSLYDAASKL
SATTAYISDK RTAIDLAVIK SDVQQTAGTI RWIDTRAMIA DPLTKSHPGH YLRHVLKTGY
WSIVEEGTAL QRKALERQEC HQLFLVVGNR VGPGSYGDQI DTALLKKTYN VTTQARSILN
RNAPTPAEPS
//
