ID A0A1Q9J1P0_9FIRM Unreviewed; 528 AA.
AC A0A1Q9J1P0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=K+/H+ antiporter {ECO:0000313|EMBL:OLR38746.1};
GN ORFNames=BIV16_11815 {ECO:0000313|EMBL:OLR38746.1};
OS Roseburia sp. 831b.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=1261635 {ECO:0000313|EMBL:OLR38746.1, ECO:0000313|Proteomes:UP000186530};
RN [1] {ECO:0000313|EMBL:OLR38746.1, ECO:0000313|Proteomes:UP000186530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=831b {ECO:0000313|EMBL:OLR38746.1,
RC ECO:0000313|Proteomes:UP000186530};
RX PubMed=27613689;
RA Trachsel J., Bayles D.O., Looft T., Levine U.Y., Allen H.K.;
RT "Function and Phylogeny of Bacterial Butyryl Coenzyme A:Acetate
RT Transferases and Their Diversity in the Proximal Colon of Swine.";
RL Appl. Environ. Microbiol. 82:6788-6798(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLR38746.1}.
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DR EMBL; MJHW01000008; OLR38746.1; -; Genomic_DNA.
DR RefSeq; WP_075680727.1; NZ_MJHW01000008.1.
DR AlphaFoldDB; A0A1Q9J1P0; -.
DR STRING; 1261635.BIV16_11815; -.
DR OrthoDB; 9810759at2; -.
DR Proteomes; UP000186530; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR PANTHER; PTHR32507:SF7; K(+)_H(+) ANTIPORTER NHAP2; 1.
DR PANTHER; PTHR32507; NA(+)/H(+) ANTIPORTER 1; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02080; TrkA_C; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186530};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 395..460
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 461..528
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 528 AA; 58026 MW; DF1EC09F82186E9F CRC64;
MTTGILIVSI VLLLCVMAEK CSDKFGMPAL ILFMFIGMLF GSDGIAKIQF DNYKLTEEIC
SIALIFIMFY GGFNTKWKAA KPVVGKSILL STAGVVLTAG ITAVLCYFVL KFSFSESFLI
GAVLSATDAA SVFAILRKQK LNLKDGTASI LELESGSNDP VAYLLTLVGI SLMKQDGTNT
VWLLILLQLV VGTLFGVGFA AVSIWLMRKT RLISEGLETI FLISFILLCY GVTKVAWGNP
YLSVYLMGIL IGNSKIKSKQ VLIPFFDGVT GLAQILIFFL LGLLTFPHKM PQIIPTALCV
TVILTLIARP IAVFSLLKPF GCSTRQCLLI AWAGLRGASS SVFAIMAVAS GMSMSYDLFH
IVFLVSLFSV SVQGGALPWM VQRLKMRDDN ADVRKTFNDY QDETSFTMMR MYIPKGHNWE
NKCIREVTMP TGALALMIKR KDETIITKGD TKILAGDSVI LSVPPYEPDG EELQEEAIEK
GHPWCNQVIS SLKLSTDELI IMIVRGNTTI IPDGKTKILE HDKVVFCR
//
