ID A0A1Q9J3Z6_9FIRM Unreviewed; 799 AA.
AC A0A1Q9J3Z6;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN ORFNames=BIV16_08490 {ECO:0000313|EMBL:OLR39576.1};
OS Roseburia sp. 831b.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=1261635 {ECO:0000313|EMBL:OLR39576.1, ECO:0000313|Proteomes:UP000186530};
RN [1] {ECO:0000313|EMBL:OLR39576.1, ECO:0000313|Proteomes:UP000186530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=831b {ECO:0000313|EMBL:OLR39576.1,
RC ECO:0000313|Proteomes:UP000186530};
RX PubMed=27613689;
RA Trachsel J., Bayles D.O., Looft T., Levine U.Y., Allen H.K.;
RT "Function and Phylogeny of Bacterial Butyryl Coenzyme A:Acetate
RT Transferases and Their Diversity in the Proximal Colon of Swine.";
RL Appl. Environ. Microbiol. 82:6788-6798(2016).
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLR39576.1}.
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DR EMBL; MJHW01000006; OLR39576.1; -; Genomic_DNA.
DR RefSeq; WP_075680112.1; NZ_MJHW01000006.1.
DR AlphaFoldDB; A0A1Q9J3Z6; -.
DR STRING; 1261635.BIV16_08490; -.
DR OrthoDB; 9776025at2; -.
DR Proteomes; UP000186530; Unassembled WGS sequence.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000186530};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 10..104
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 518..788
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
SQ SEQUENCE 799 AA; 86226 MW; B5A5D09311F76A6B CRC64;
MPIRITGLNS GLDTESIISA LVSAYSYKTN KYKKAQTKLA WKQDAWKTLN SKIYSFYNNV
GNMKLSSAYN MKTATISDTT KASVTASSKA VNGSYSIQVT QLAKTGYLTG GQLSSGVTYS
TKMSELGFSG KGKITVGTGS SSKDITVSAD TTVSEFVTNL KEAGVNASYD ENNRRFYISA
KESGAANDFT LTGADAKGTE LINDLKLSVV TSSDTKAYKD LNNEYYGQDF ASIRDAKKTA
TNTVTNLTAK NQNYNSALSY AKALNSVNQV ASLATDAAKK DDYNQMVALA QKASLTNVWV
DNDGALYNYD ESTKKYTNVK EYTGGSYNEA TGEYTDADGN VITGGVYNDN GTYTVTKEAL
DTENLMTADA KLQELAIEFG MSKTETVKGK DGSETTKTVA DSDALNTFKK NLSTVSSLGS
QSGNNTELGN LIKEIDDTNA AGGTTDVATK ISEYESTVST NEAEIASANQ TLSEYSKITA
TMTDNDLAAL QQKVDYAHQV ATGSVTIASS AGATRIEGQD ATIYVNGAEY TGSTNNFSIN
GLTINATGVT GSSYDATEQS AVNVTVNTDT QGIYDKIKDM LTQYNSLINE ITSLYNADSA
KGYEPLTDDE KDAMSDTEVE KWEEKIKASL LRRDDTLESV MNGMTAAMSK SYTINGKSYN
LSSFGISTLG FLNAAENEQY AYHIDGDEDD TATSGKADKL MAAITQDPDS VVSFMQQLAD
GLYKNIDARM KSSTISSVYK VYNDKEMASE YSDYTTLISK WEDKLQEKED YYYKKFSSME
TALSKLNSQT SSLSNILGS
//
