ID A0A1Q9J771_9FIRM Unreviewed; 532 AA.
AC A0A1Q9J771;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=DNA (cytosine-5-)-methyltransferase {ECO:0000256|ARBA:ARBA00011975};
DE EC=2.1.1.37 {ECO:0000256|ARBA:ARBA00011975};
GN ORFNames=BIV16_00960 {ECO:0000313|EMBL:OLR41102.1};
OS Roseburia sp. 831b.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=1261635 {ECO:0000313|EMBL:OLR41102.1, ECO:0000313|Proteomes:UP000186530};
RN [1] {ECO:0000313|EMBL:OLR41102.1, ECO:0000313|Proteomes:UP000186530}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=831b {ECO:0000313|EMBL:OLR41102.1,
RC ECO:0000313|Proteomes:UP000186530};
RX PubMed=27613689;
RA Trachsel J., Bayles D.O., Looft T., Levine U.Y., Allen H.K.;
RT "Function and Phylogeny of Bacterial Butyryl Coenzyme A:Acetate
RT Transferases and Their Diversity in the Proximal Colon of Swine.";
RL Appl. Environ. Microbiol. 82:6788-6798(2016).
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. C5-methyltransferase family. {ECO:0000256|PROSITE-
CC ProRule:PRU01016}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLR41102.1}.
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DR EMBL; MJHW01000001; OLR41102.1; -; Genomic_DNA.
DR RefSeq; WP_075678536.1; NZ_MJHW01000001.1.
DR AlphaFoldDB; A0A1Q9J771; -.
DR STRING; 1261635.BIV16_00960; -.
DR OrthoDB; 9813719at2; -.
DR Proteomes; UP000186530; Unassembled WGS sequence.
DR GO; GO:0003886; F:DNA (cytosine-5-)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:UniProtKB-KW.
DR Gene3D; 3.90.120.10; DNA Methylase, subunit A, domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR10629; CYTOSINE-SPECIFIC METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10629:SF50; DNA (CYTOSINE-5)-METHYLTRANSFERASE CMT3; 1.
DR Pfam; PF00145; DNA_methylase; 1.
DR PRINTS; PR00105; C5METTRFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51679; SAM_MT_C5; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01016}; Reference proteome {ECO:0000313|Proteomes:UP000186530};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01016};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01016}.
FT ACT_SITE 80
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01016"
SQ SEQUENCE 532 AA; 59492 MW; AAECB3941F1B570A CRC64;
MIKGELIVDN FAGGGGASTG IELATGYSVD IAINHDPEAI RMHKANHPNT KHYCENVWAV
DPVKACGGHP VALAWFSPDC KHFSKAKGGK PKDKNIRGLA WVACRWAGLV RPRVIMLENV
EEFKTWGPLN RRHHPIKSKQ GKTFERFIQQ LTDLGYEVQF KELIAADYGA PTMRKRFFMI
ARCDGKPIVW PEPTHGPADS EAVKAGLLKP YVGAYTQIDF SRPCPSIFDT SEEIKEKYGI
RAVRPLAKKT MDRIARGLKK FVLDNPEPFI IQCNHGGERR PNDIREPMPT ITGKHGYGIV
EPYMVQIGQT GFTKDRSKDV REPLTTIVSK NEHCLISPTL IQYHSETARG EVRGQTIEDP
IMTVDSSNRY GLVTSFLSKF YKSGTGQDLR EPLHTITTSA GHFGEVRAFL IKYYGDATGQ
DIEQPLDTVT TKDRFGLVTI EGVDYQIVDI GLRMLEPREL YGCQGFPGDY IIDHDYTGKT
YPRSEQVRRC GNAVCPPIPA ALVKANLPEL CVAERTPNMK IEAEQTGQLR FA
//
