ID A0A1Q9JML9_9FIRM Unreviewed; 436 AA.
AC A0A1Q9JML9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Integral membrane bound transporter domain-containing protein {ECO:0000259|Pfam:PF13515};
GN ORFNames=BIV20_09025 {ECO:0000313|EMBL:OLR57385.1};
OS Roseburia sp. 499.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=1261634 {ECO:0000313|EMBL:OLR57385.1, ECO:0000313|Proteomes:UP000186602};
RN [1] {ECO:0000313|EMBL:OLR57385.1, ECO:0000313|Proteomes:UP000186602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=499 {ECO:0000313|EMBL:OLR57385.1,
RC ECO:0000313|Proteomes:UP000186602};
RX PubMed=27613689;
RA Trachsel J., Bayles D.O., Looft T., Levine U.Y., Allen H.K.;
RT "Function and Phylogeny of Bacterial Butyryl Coenzyme A:Acetate
RT Transferases and Their Diversity in the Proximal Colon of Swine.";
RL Appl. Environ. Microbiol. 82:6788-6798(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLR57385.1}.
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DR EMBL; MJID01000010; OLR57385.1; -; Genomic_DNA.
DR RefSeq; WP_075720697.1; NZ_MJID01000010.1.
DR AlphaFoldDB; A0A1Q9JML9; -.
DR STRING; 1261634.BIV20_09025; -.
DR OrthoDB; 1653617at2; -.
DR Proteomes; UP000186602; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR Gene3D; 3.30.1240.10; -; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR049453; Memb_transporter_dom.
DR PANTHER; PTHR10000:SF58; MANNOSYL-3-PHOSPHOGLYCERATE PHOSPHATASE-RELATED; 1.
DR PANTHER; PTHR10000; PHOSPHOSERINE PHOSPHATASE; 1.
DR Pfam; PF13515; FUSC_2; 1.
DR Pfam; PF08282; Hydrolase_3; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186602};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..161
FT /note="Integral membrane bound transporter"
FT /evidence="ECO:0000259|Pfam:PF13515"
SQ SEQUENCE 436 AA; 49744 MW; 08C97814226F7C9F CRC64;
MKSRLCNIKI PRIGLRIQKS ALSVLFCYII YILRGHQGIC FYSMLAALWC IRPYIGNTLE
MAIQRTTGTL VGALYGLIVI MIKQAFLSQP GIQYELGYFL LVSLTIIPII QTTLLLNQQN
ASYFSCVVFL SIVVIHIGDA SPFLFVWQRV LDTMIGIGVG IGINSFRLPT RKRRDILFVS
GVDDTLIGKQ EQISTYSKRE LNAMIDDGAN FTISTMRTPA ALMKVLDGIH LQIPIIAMDG
AVLYDFSSNT YVKSFVISSE KSKEISELIK AEGLNCFANV IIDDCLLIFY QDFKNEVEKK
VFETMHTSPY RNYINANVPE NVCVVYFMLL AETERLQRFY ELLQEKGYGK SLKILFYASE
DYPGYSYIKI YNKNTSRENM LDYLKKMTGL EKTVTFGSIP DKYDIIVKKE ENDKVAKTLR
QMYAVPFWKG NEKHGD
//
