ID A0A1Q9LBV9_9PSEU Unreviewed; 1142 AA.
AC A0A1Q9LBV9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=XRE family transcriptional regulator {ECO:0008006|Google:ProtNLM};
GN ORFNames=BJP25_05265 {ECO:0000313|EMBL:OLR89495.1};
OS Actinokineospora bangkokensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinokineospora.
OX NCBI_TaxID=1193682 {ECO:0000313|EMBL:OLR89495.1, ECO:0000313|Proteomes:UP000186040};
RN [1] {ECO:0000313|EMBL:OLR89495.1, ECO:0000313|Proteomes:UP000186040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=44EHW {ECO:0000313|EMBL:OLR89495.1,
RC ECO:0000313|Proteomes:UP000186040};
RA Greule A., Intra B., Flemming S., Rommel M.G., Panbangred W., Bechthold A.;
RT "The Draft Genome Sequence of Actinokineospora bangkokensis 44EHWT reveals
RT the biosynthetic pathway of antifungal compounds Thailandins with unusual
RT extender unit butylmalonyl-CoA.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLR89495.1}.
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DR EMBL; MKQR01000032; OLR89495.1; -; Genomic_DNA.
DR RefSeq; WP_075978678.1; NZ_MKQR01000032.1.
DR AlphaFoldDB; A0A1Q9LBV9; -.
DR STRING; 1193682.BJP25_05265; -.
DR OrthoDB; 581105at2; -.
DR Proteomes; UP000186040; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF13560; HTH_31; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF17874; TPR_MalT; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SMART; SM00028; TPR; 7.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; Reference proteome {ECO:0000313|Proteomes:UP000186040};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 11..66
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT DOMAIN 68..165
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT REPEAT 811..844
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DNA_BIND 68..165
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ SEQUENCE 1142 AA; 120936 MW; 2D122EDC890FFF6E CRC64;
MVDRGAFGAA VRAHRLRAGL TQGELAERAG LSVRALRYIE RGGVGRPRPE SVRRLAEAVG
VEVGVLSAAV VPSPQLRVGV LGPFTVTRDD VRLRAGAVKQ RVLLALLALH PGERVSHAEI
VDVLWGEDPP ASCLGLVHTY VSRLRGTLDA GDAIASEPGG YRLDATAEEL DLLRFTELVE
RARATGGAAA VDLLGRALDC WRGPVLADLP DRLRAHPTAE ALAVRRREVA LEHADLALAL
GAHTAVVRVL RALVPHDPLH EGLHARLGLA LSGTGEQAEA LRVLTDLRSR LDEELGVEPG
QEVRAAHVRV LRAAPAPGPP PAGPDPALPV PAQLPAESPG FVGRHDPLGK LDELAGATDS
GVVPVVVSGT AGVGKTALAL RWAHRARHRF PDGQLSANLR GHAAGTPLST HQVLVRFLHA
LGVAPERVPA DTDEAAGLYR TLLAGRRVLV LLDNAATAEQ VRPLLPGAPG CLVLVTSRDR
LAGLTAQDGA HQLPLDVLGP AEAAELLGRM VGTARLRREP AAAAEVAEVC GHLPLALRIA
GANLAVRPQV SIADYTRELR DRGRLAGLAV PGDQSAAVRA AFDLSYAKLA PAARRLFRLL
GLAPGAEVDA PATAALGGLA VPEAARLLRV LHSGNLIRET APGRYALHDL LRDYARARAA
DEDDDHRGAL VGLFDHYLAE VEAHSAVLWQ VGAPRRTGTE DTALAWLDLE LGTLVAAATE
AAGLGLPRYA WRFAEALRPF FFNRGHGADG LAVARAALAA ARACGDVDAE ASVHDLLGVI
HCNLSDYAAA TEHHGWALEL SQGTGNRVVE AAALHNLGRA HSQLGQPAQA SAYYERSLRL
HRDIGNRFGE AGALHYLGVA ALSLGNPEEA VARHTEALEL SARIGHRHVQ AAASQGLGLA
HWAMGDLPLA TRRYRHALSV CRRYGYRHGE VSMLVCLAET GCDAGDYPAA TAQVRHAMEA
NRDLGERRHE VSCLDILGTI AQRTGEWSAA AEHYARALDL AREIRFGYGE ASVRMGQCSL
ARRTGDPGAA IDHGLGALTL MRASGMRLLE ARALTELAHA HLDAADPDTA ADHVERAITT
AHRTGQRLTE ARARHVRALL HQRAGNRPAA VLDWRAALPV FTALAVPEAD HVQALLAAFT
AT
//
