ID A0A1Q9LEQ4_9PSEU Unreviewed; 676 AA.
AC A0A1Q9LEQ4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Dehydrogenase {ECO:0000313|EMBL:OLR90449.1};
GN ORFNames=BJP25_27785 {ECO:0000313|EMBL:OLR90449.1};
OS Actinokineospora bangkokensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinokineospora.
OX NCBI_TaxID=1193682 {ECO:0000313|EMBL:OLR90449.1, ECO:0000313|Proteomes:UP000186040};
RN [1] {ECO:0000313|EMBL:OLR90449.1, ECO:0000313|Proteomes:UP000186040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=44EHW {ECO:0000313|EMBL:OLR90449.1,
RC ECO:0000313|Proteomes:UP000186040};
RA Greule A., Intra B., Flemming S., Rommel M.G., Panbangred W., Bechthold A.;
RT "The Draft Genome Sequence of Actinokineospora bangkokensis 44EHWT reveals
RT the biosynthetic pathway of antifungal compounds Thailandins with unusual
RT extender unit butylmalonyl-CoA.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLR90449.1}.
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DR EMBL; MKQR01000026; OLR90449.1; -; Genomic_DNA.
DR RefSeq; WP_075977122.1; NZ_MKQR01000026.1.
DR AlphaFoldDB; A0A1Q9LEQ4; -.
DR STRING; 1193682.BJP25_27785; -.
DR OrthoDB; 7376058at2; -.
DR Proteomes; UP000186040; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR PANTHER; PTHR43105:SF14; POSSIBLE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00490; MOLYBDOPTERIN_PROK_2; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Reference proteome {ECO:0000313|Proteomes:UP000186040}.
FT DOMAIN 1..58
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 676 AA; 73292 MW; A06B75B2A8E7208F CRC64;
MASTRLITCN LCEACCGLQV EVEQDRVTSV SGDPRDPLSR GHLCPKGVAI GDVHADGKRL
RTPVRKTATG WQEIGWDAAL DEVATRLADA RERHGRNSVA VYLGNPTAHS LGALTHGTAF
FGMLRTRNRY SATSVDQLPH HLAAYLLYGH QLLLPIPDID RTDHFLLVGG NPLVSNGSLM
TVPDFANRRK ELRARGGKFV VLDPRRTETA KVADEHHFVR PGTDAALLLA LVRTVLHEGL
ATPPPYVDGV AELTEAVAGF TPEWAAPITG VDAGTIERLA REFATAERAV AHGRTGVSMQ
RHGAVCQWAV QVLNAITGNL DRPGGALATR PAVDILKMVG PGHFGVWRSR VRGLPEFAGE
LPVSVLAEEI ETPGEGQVKA AVVHAGNPVL STPDGKRLAK ALGQLDFLVA IDIKVTETSE
HADIVLPPTT LLERDHYDLI FHALAVRDTA RYSPPAIAKP ADARHDWEIF RDLGLRYAKR
VKTPLATRLR LRLRPTVLLD LLLRVGPHKL TLRKLRKNPS GVDLGPLAPS FPHRLRTKDK
RVQIAPEMML DALAAVRDMT AEDGLLLIGR RHLRANNSWM NDVARLTRGR PRHHLLMHPK
DLADNGLVDG ADVLVRSAVG SVRVPVTASE DVMPGVVSLP HGYRGTSAND LTDPAVVDEV
SGNAVLNGVP VHVTPV
//
