ID A0A1Q9LEV4_9PSEU Unreviewed; 379 AA.
AC A0A1Q9LEV4;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Inosine 5-monophosphate dehydrogenase {ECO:0000313|EMBL:OLR90571.1};
GN ORFNames=BJP25_28530 {ECO:0000313|EMBL:OLR90571.1};
OS Actinokineospora bangkokensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinokineospora.
OX NCBI_TaxID=1193682 {ECO:0000313|EMBL:OLR90571.1, ECO:0000313|Proteomes:UP000186040};
RN [1] {ECO:0000313|EMBL:OLR90571.1, ECO:0000313|Proteomes:UP000186040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=44EHW {ECO:0000313|EMBL:OLR90571.1,
RC ECO:0000313|Proteomes:UP000186040};
RA Greule A., Intra B., Flemming S., Rommel M.G., Panbangred W., Bechthold A.;
RT "The Draft Genome Sequence of Actinokineospora bangkokensis 44EHWT reveals
RT the biosynthetic pathway of antifungal compounds Thailandins with unusual
RT extender unit butylmalonyl-CoA.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC {ECO:0000256|ARBA:ARBA00005502}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLR90571.1}.
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DR EMBL; MKQR01000026; OLR90571.1; -; Genomic_DNA.
DR RefSeq; WP_075977244.1; NZ_MKQR01000026.1.
DR AlphaFoldDB; A0A1Q9LEV4; -.
DR STRING; 1193682.BJP25_28530; -.
DR OrthoDB; 9805398at2; -.
DR Proteomes; UP000186040; Unassembled WGS sequence.
DR GO; GO:0003938; F:IMP dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR005990; IMP_DH.
DR InterPro; IPR005992; IMP_DH-rel2.
DR InterPro; IPR001093; IMP_DH_GMPRt.
DR NCBIfam; TIGR01304; IMP_DH_rel_2; 1.
DR PANTHER; PTHR11911:SF85; INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR Pfam; PF00478; IMPDH; 1.
DR SMART; SM01240; IMPDH; 1.
DR SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000186040}.
FT DOMAIN 18..306
FT /note="IMP dehydrogenase/GMP reductase"
FT /evidence="ECO:0000259|Pfam:PF00478"
SQ SEQUENCE 379 AA; 39106 MW; 80F3356FAED60F71 CRC64;
MRDLVDIGMG RTARRAFGLD DVEIVPSRRT RSSSDVATTW QIDAYRFDIP LVTHPTDAVV
SPAAAVAVGK LGGLGVLNAE GVWARHTDPE AALARLVEAA DKGEDPAVLV RVLQELHAAP
IQEDLVTEAV RQVRESGVTA AARVSPQNAA ALAPLLIAAG VEILVVQGTI VSAEHVAKGD
GEPLNLKSFI GGLDIPVIAG GAHDYRTAMH LMRTGAAGVV VGYGHVDGVT STDAALGIGV
PMATAIVDAA AARRDYLDET GGRYVHVIAD GEVHTSGDIA KSIACGADAV MLGAPLAAAA
EAPGGGLYWT AAAAHPSLPR SRVLPVAEET GIPLQQLLFG PSGEADGQVN LFGALRRAMA
KTGYSDLKEF QRVGLTVRG
//
