ID A0A1Q9LPB7_9PSEU Unreviewed; 305 AA.
AC A0A1Q9LPB7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Sphingosine kinase {ECO:0000313|EMBL:OLR93865.1};
GN ORFNames=BJP25_14090 {ECO:0000313|EMBL:OLR93865.1};
OS Actinokineospora bangkokensis.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinokineospora.
OX NCBI_TaxID=1193682 {ECO:0000313|EMBL:OLR93865.1, ECO:0000313|Proteomes:UP000186040};
RN [1] {ECO:0000313|EMBL:OLR93865.1, ECO:0000313|Proteomes:UP000186040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=44EHW {ECO:0000313|EMBL:OLR93865.1,
RC ECO:0000313|Proteomes:UP000186040};
RA Greule A., Intra B., Flemming S., Rommel M.G., Panbangred W., Bechthold A.;
RT "The Draft Genome Sequence of Actinokineospora bangkokensis 44EHWT reveals
RT the biosynthetic pathway of antifungal compounds Thailandins with unusual
RT extender unit butylmalonyl-CoA.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLR93865.1}.
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DR EMBL; MKQR01000009; OLR93865.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q9LPB7; -.
DR STRING; 1193682.BJP25_14090; -.
DR OrthoDB; 142078at2; -.
DR Proteomes; UP000186040; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 2.60.200.40; -; 1.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR InterPro; IPR045540; YegS/DAGK_C.
DR PANTHER; PTHR12358:SF106; LIPID KINASE YEGS; 1.
DR PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR Pfam; PF19279; YegS_C; 1.
DR SMART; SM00046; DAGKc; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OLR93865.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000186040};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 10..144
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
SQ SEQUENCE 305 AA; 31573 MW; 6F4636FA4838E37E CRC64;
MCAGDREVAV AGLRVAVVVH AASGHGAAAR VAPRVVERLS GVVSRVTVVE ADTVERSRAG
LLRARDAGLD VVVVVGGDGS VHQAVQFCAE HGVALAVVPS GTGNDLGRAL GVPARAAEAV
EAVVAALGAG ARRRVDLGRV AGGAWFASVL CAGFDSAVNE RVNRMRWPHG RRRYDLAIVA
ELAALSQRTL VVDTDGGRLE LAATMVAVGN TGFYGGGIPV CPRADPADGV FDLTVVGQMS
RWDLVRMLPT LRTGEHVGHP AVRTLRARRV SLGGDNEWVA YADGERLGPL PVVVECVPGA
LEVVG
//
