ID A0A1Q9NTN1_9ARCH Unreviewed; 414 AA.
AC A0A1Q9NTN1;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Putative tRNA sulfurtransferase {ECO:0000313|EMBL:OLS25458.1};
DE EC=2.8.1.4 {ECO:0000313|EMBL:OLS25458.1};
GN Name=thiI_1 {ECO:0000313|EMBL:OLS25458.1};
GN ORFNames=HeimC3_14450 {ECO:0000313|EMBL:OLS25458.1};
OS Candidatus Heimdallarchaeota archaeon LC_3.
OC Archaea; Asgard group; Candidatus Heimdallarchaeota.
OX NCBI_TaxID=1841598 {ECO:0000313|EMBL:OLS25458.1, ECO:0000313|Proteomes:UP000186063};
RN [1] {ECO:0000313|EMBL:OLS25458.1, ECO:0000313|Proteomes:UP000186063}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LC_3 {ECO:0000313|EMBL:OLS25458.1};
RX PubMed=28077874; DOI=10.1038/nature21031;
RA Zaremba-Niedzwiedzka K., Caceres E.F., Saw J.H., Backstrom D.,
RA Juzokaite L., Vancaester E., Seitz K.W., Anantharaman K., Starnawski P.,
RA Kjeldsen K.U., Scott M.B., Nunoura T., Banfield J.F., Schramm A.,
RA Baker B.J., Spang A., Ettema T.J.G.;
RT "Asgard archaea illuminate the origin of eukaryotic cellular complexity.";
RL Nature 541:353-358(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLS25458.1}.
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DR EMBL; MDVS01000023; OLS25458.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q9NTN1; -.
DR Proteomes; UP000186063; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004810; F:CCA tRNA nucleotidyltransferase activity; IEA:InterPro.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0140741; F:tRNA-uracil-4 sulfurtransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006400; P:tRNA modification; IEA:UniProt.
DR CDD; cd11716; THUMP_ThiI; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR020536; ThiI_AANH.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR43209; TRNA SULFURTRANSFERASE; 1.
DR PANTHER; PTHR43209:SF1; TRNA SULFURTRANSFERASE; 1.
DR Pfam; PF02568; ThiI; 1.
DR Pfam; PF02926; THUMP; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF143437; THUMP domain-like; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:OLS25458.1};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555}.
FT DOMAIN 98..207
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 414 AA; 47902 MW; 58797CACF7075897 CRC64;
MTNYSYADYI SFLLYQKKIY QLSHFRCVFM KKNQTNLYNM VLVRHGGEIG IKSRKTRSRM
IKLLNDTIKY KTQHLNVESV IHKYTRTLVT SSEFSPTKIA KYIANHICGV DSTSPVQFIE
IKTLDTILSS GVNYALTFLE KDDSFGFKVR RTGNHSFSSM ELASLLGSKV LKESTIKGFN
NNVNLTNPDY LFQLEIKYDY CFLFHNSFSG LNGLPQGSQG LILANIRSWT PDYLAACMML
RRGAKIIPIF FSSNKQKKLR KIQTFFDEVR LGSKERDFLV DLEKDFLKKW KEKISQIELC
QACHFFTELV SKYLYESEED YLGIVNGTSL KDVSSNFLKK LDVLPNIPIH RPYLLNFDKN
IPEPLKFMLE NSENNISCCE IQEKRFFSSE NNLSDDILKE IDSDAKIIVE KLVS
//
