ID A0A1Q9P6Z5_9ARCH Unreviewed; 284 AA.
AC A0A1Q9P6Z5;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=2-oxoacid dehydrogenase acyltransferase catalytic domain-containing protein {ECO:0000259|Pfam:PF00198};
GN ORFNames=HeimAB125_20380 {ECO:0000313|EMBL:OLS30140.1};
OS Candidatus Heimdallarchaeota archaeon AB_125.
OC Archaea; Asgard group; Candidatus Heimdallarchaeota.
OX NCBI_TaxID=1841596 {ECO:0000313|EMBL:OLS30140.1, ECO:0000313|Proteomes:UP000186239};
RN [1] {ECO:0000313|EMBL:OLS30140.1, ECO:0000313|Proteomes:UP000186239}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AB_125 {ECO:0000313|EMBL:OLS30140.1};
RX PubMed=28077874; DOI=10.1038/nature21031;
RA Zaremba-Niedzwiedzka K., Caceres E.F., Saw J.H., Backstrom D.,
RA Juzokaite L., Vancaester E., Seitz K.W., Anantharaman K., Starnawski P.,
RA Kjeldsen K.U., Scott M.B., Nunoura T., Banfield J.F., Schramm A.,
RA Baker B.J., Spang A., Ettema T.J.G.;
RT "Asgard archaea illuminate the origin of eukaryotic cellular complexity.";
RL Nature 541:353-358(2017).
CC -!- COFACTOR:
CC Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC Evidence={ECO:0000256|ARBA:ARBA00001938};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLS30140.1}.
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DR EMBL; MEHH01000168; OLS30140.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q9P6Z5; -.
DR Proteomes; UP000186239; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR PANTHER; PTHR43178; DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX; 1.
DR PANTHER; PTHR43178:SF5; LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL; 1.
DR Pfam; PF00198; 2-oxoacid_dh; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
PE 4: Predicted;
FT DOMAIN 18..153
FT /note="2-oxoacid dehydrogenase acyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00198"
FT DOMAIN 194..272
FT /note="2-oxoacid dehydrogenase acyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00198"
SQ SEQUENCE 284 AA; 32309 MW; EF6E78B9C2D6B481 CRC64;
MKDISLIKLK MSKKKPEHTV RKMSVARRIL ADFNDVAAKF PRVQGVVEID ITEGRKKIKE
YKEKNNYSIS LTSWIAKCVS KAVKENPKLN SFRKRGKKII VFENVDISIM VEVTTKDGKY
VPFNHVIRKV ETKSVKEITD EIRSVQNKKI EEKEQITGDS GSFSGLIMLI PRKVRQFFIK
RKLKNPFFVQ KLIGTVGITS LGMFAKNIFG WAVPFSDRTC NVALGGLQRV GWEIDGKLQA
RDVICVLFMI DHNLVDGAPI ARFISRVAEL MGQAYGLEDI TKKE
//
