ID A0A1Q9RZ23_9PSEU Unreviewed; 554 AA.
AC A0A1Q9RZ23;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=FAD-binding dehydrogenase {ECO:0000313|EMBL:OLT01905.1};
GN ORFNames=BJF90_30620 {ECO:0000313|EMBL:OLT01905.1};
OS Pseudonocardia sp. CNS-004.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Pseudonocardia.
OX NCBI_TaxID=1904967 {ECO:0000313|EMBL:OLT01905.1, ECO:0000313|Proteomes:UP000186863};
RN [1] {ECO:0000313|EMBL:OLT01905.1, ECO:0000313|Proteomes:UP000186863}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CNS-004 {ECO:0000313|EMBL:OLT01905.1,
RC ECO:0000313|Proteomes:UP000186863};
RX PubMed=27902408; DOI=10.1099/mic.0.000386;
RA Schorn M.A., Alanjary M.M., Aguinaldo K., Korobeynikov A., Podell S.,
RA Patin N., Lincecum T., Jensen P.R., Ziemert N., Moore B.S.;
RT "Sequencing rare marine actinomycete genomes reveals high density of unique
RT natural product biosynthetic gene clusters.";
RL Microbiology 162:2075-2086(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLT01905.1}.
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DR EMBL; MKJV01000092; OLT01905.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1Q9RZ23; -.
DR OrthoDB; 9813348at2; -.
DR Proteomes; UP000186863; Unassembled WGS sequence.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR014614; KsdD_DH.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR43260; 3-KETOSTEROID-DELTA-1-DEHYDROGENASE; 1.
DR PANTHER; PTHR43260:SF1; KSDD-LIKE STEROID DEHYDROGENASE RV0785; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR PIRSF; PIRSF036654; UCP036654; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000186863}.
FT DOMAIN 4..536
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 554 AA; 59131 MW; FEC5ECB97B0124A3 CRC64;
MDADVIVVGA GLAGLVATAE LAGAGKKVLL LDQEPEASLG GQAFWSFGGL FLVDSPEQRR
MGVRDSVDLA LQDWLGTAGF DRGVDDPAGE DFWARQWATA YVDFAHAEKR AWLHGLGVRW
FPVVGWAERG GGLADGHGNS VPRFHIVWGT GPGLLDPFVR QVRDAAARGL VELRFRHRVD
GLSVTDGVVD GVRGAVLEPS STARGTASSR TGVGEFELHA QAVIVTSGGI GADHDLVRAN
WPSRLGAAPK QLISGVPEHV DGRLLGITEG AGGRVVNRDR MWHYTEGIRN WDPIWARHGI
RILAGPSSLW FDALGRRFPA PCFPGFDTLA TLKAITATGH DHSWFVLTQK IIEKEFALSG
SEQNPDLTGK DLRKVLSRVR PGAPAPVEAF KEHGADFVVA DTLPELVAGM NALTDEPLID
LAVLEGQIAA RDREIDNPFT KDLQVTALHG ARRYRGDRLI RTATPHKVLD PANGPLIAVQ
LHVLTRKTLG GLQTDLTGRV LRPDATPFPG LYAAGEVAGF GGGGVHGYAS LEGTFLGGCL
FSGRQAGRAV SLAV
//
