ID A0A1Q9TI05_9ACTN Unreviewed; 307 AA.
AC A0A1Q9TI05;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Sphingomyelin phosphodiesterase {ECO:0000313|EMBL:OLT25044.1};
GN ORFNames=BJF83_05520 {ECO:0000313|EMBL:OLT25044.1};
OS Nocardiopsis sp. CNR-923.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Nocardiopsis.
OX NCBI_TaxID=1904965 {ECO:0000313|EMBL:OLT25044.1, ECO:0000313|Proteomes:UP000185703};
RN [1] {ECO:0000313|EMBL:OLT25044.1, ECO:0000313|Proteomes:UP000185703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CNR-923 {ECO:0000313|EMBL:OLT25044.1,
RC ECO:0000313|Proteomes:UP000185703};
RX PubMed=27902408; DOI=10.1099/mic.0.000386;
RA Schorn M.A., Alanjary M.M., Aguinaldo K., Korobeynikov A., Podell S.,
RA Patin N., Lincecum T., Jensen P.R., Ziemert N., Moore B.S.;
RT "Sequencing rare marine actinomycete genomes reveals high density of unique
RT natural product biosynthetic gene clusters.";
RL Microbiology 162:2075-2086(2016).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLT25044.1}.
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DR EMBL; MKKC01000131; OLT25044.1; -; Genomic_DNA.
DR RefSeq; WP_075927928.1; NZ_MKKC01000131.1.
DR AlphaFoldDB; A0A1Q9TI05; -.
DR STRING; 1904965.BJF83_05520; -.
DR OrthoDB; 9787701at2; -.
DR Proteomes; UP000185703; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0004767; F:sphingomyelin phosphodiesterase activity; IEA:InterPro.
DR CDD; cd09078; nSMase; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR038772; Sph/SMPD2-like.
DR InterPro; IPR017766; Sphingomyelinase/PLipase_C.
DR NCBIfam; TIGR03395; sphingomy; 1.
DR PANTHER; PTHR16320:SF23; SPHINGOMYELINASE DDB_G0288017; 1.
DR PANTHER; PTHR16320; SPHINGOMYELINASE FAMILY MEMBER; 1.
DR Pfam; PF03372; Exo_endo_phos; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000185703};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..307
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013023027"
FT DOMAIN 27..301
FT /note="Endonuclease/exonuclease/phosphatase"
FT /evidence="ECO:0000259|Pfam:PF03372"
SQ SEQUENCE 307 AA; 33837 MW; 6F24D63E4D823428 CRC64;
MILAAIIPLL ATAAPAAADD GQAPRIATYN AYLLPTALYP NWGQSIRADL IARDGVVSGQ
DVVVLQELFD NSSAAVLRGG IAQEYPHGTP VVGRSRDGWD RTTGYRPFTT TNGGVSIHST
WPITRQEQHI FSRSCGSDWF ANKGFAYVEL DTPDGPLHVL GTHMQSEDSA CSDDEDEEIR
THQLGQIRGF IDATVPDDEP VYLAGDLNIV GGGMEWDQAL KRLDAVEPTH AGAPFSWDTE
TNSIAEYNYP DWSPEHLDHV LPIRNAAAPE SYVNETRDVH SEPWTVWSWG RSYTYDDYSD
HYPVFGG
//
