ID A0A1Q9V7T8_9MICO Unreviewed; 343 AA.
AC A0A1Q9V7T8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=CNNM transmembrane domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BJF88_05515 {ECO:0000313|EMBL:OLT45999.1};
OS Cellulosimicrobium sp. CUA-896.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC Promicromonosporaceae; Cellulosimicrobium.
OX NCBI_TaxID=1517881 {ECO:0000313|EMBL:OLT45999.1, ECO:0000313|Proteomes:UP000185790};
RN [1] {ECO:0000313|EMBL:OLT45999.1, ECO:0000313|Proteomes:UP000185790}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CUA-896 {ECO:0000313|EMBL:OLT45999.1,
RC ECO:0000313|Proteomes:UP000185790};
RX PubMed=27902408; DOI=10.1099/mic.0.000386;
RA Schorn M.A., Alanjary M.M., Aguinaldo K., Korobeynikov A., Podell S.,
RA Patin N., Lincecum T., Jensen P.R., Ziemert N., Moore B.S.;
RT "Sequencing rare marine actinomycete genomes reveals high density of unique
RT natural product biosynthetic gene clusters.";
RL Microbiology 162:2075-2086(2016).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OLT45999.1}.
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DR EMBL; MKKH01000078; OLT45999.1; -; Genomic_DNA.
DR RefSeq; WP_075829702.1; NZ_MKKH01000078.1.
DR AlphaFoldDB; A0A1Q9V7T8; -.
DR OrthoDB; 110231at2; -.
DR Proteomes; UP000185790; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.90.1280.20; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR PANTHER; PTHR43099:SF4; INTEGRAL MEMBRANE PROTEIN-RELATED; 1.
DR PANTHER; PTHR43099; UPF0053 PROTEIN YRKA; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|PROSITE-ProRule:PRU01193, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000185790};
KW Transmembrane {ECO:0000256|PROSITE-ProRule:PRU01193,
KW ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|PROSITE-ProRule:PRU01193,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..203
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 281..338
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 343 AA; 36335 MW; 1AF66FCD77F0D41A CRC64;
MSNPWVVVVA TVAIIALSAF FVAVEFALLA AKRHRLEDAA PTSRAARAAL RSSNELTLLM
AGAQLGITAC TLALGAITKP AVHHWLTPVF EAWGVPLWAA DVAGFVLALV VVTFLHLVVG
EMAPKSWAIA HPERSATLLA LPMRGFMAVF RPLLRWLNAL ANRCVRAVGV EPVENVEGGG
QDPATLRHLV EHSASVGALE ASYRAQISGA LELQTLTVDA LVPAGGAPTA VPSHATAADV
RAASAASGHL RILVRNGSVV PRVVHVRDTL LEPDDRRVHD LARPGFVLES GTTVHAALAR
MRESSEHLAI VMDGDRFVGV VTLADVLRRI LPRPEEPVAT LVG
//
