ID   A0A1Q9VA56_9MICO        Unreviewed;       605 AA.
AC   A0A1Q9VA56;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Phosphohydrolase {ECO:0000313|EMBL:OLT46842.1};
GN   ORFNames=BJF88_04520 {ECO:0000313|EMBL:OLT46842.1};
OS   Cellulosimicrobium sp. CUA-896.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC   Promicromonosporaceae; Cellulosimicrobium.
OX   NCBI_TaxID=1517881 {ECO:0000313|EMBL:OLT46842.1, ECO:0000313|Proteomes:UP000185790};
RN   [1] {ECO:0000313|EMBL:OLT46842.1, ECO:0000313|Proteomes:UP000185790}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CUA-896 {ECO:0000313|EMBL:OLT46842.1,
RC   ECO:0000313|Proteomes:UP000185790};
RX   PubMed=27902408; DOI=10.1099/mic.0.000386;
RA   Schorn M.A., Alanjary M.M., Aguinaldo K., Korobeynikov A., Podell S.,
RA   Patin N., Lincecum T., Jensen P.R., Ziemert N., Moore B.S.;
RT   "Sequencing rare marine actinomycete genomes reveals high density of unique
RT   natural product biosynthetic gene clusters.";
RL   Microbiology 162:2075-2086(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OLT46842.1}.
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DR   EMBL; MKKH01000066; OLT46842.1; -; Genomic_DNA.
DR   RefSeq; WP_075829530.1; NZ_MKKH01000066.1.
DR   AlphaFoldDB; A0A1Q9VA56; -.
DR   OrthoDB; 9758038at2; -.
DR   Proteomes; UP000185790; Unassembled WGS sequence.
DR   GO; GO:0008773; F:[protein-PII] uridylyltransferase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   CDD; cd05401; NT_GlnE_GlnD_like; 1.
DR   Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR   Gene3D; 1.10.3090.10; cca-adding enzyme, domain 2; 1.
DR   InterPro; IPR005105; GlnD_Uridyltrans_N.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR043519; NT_sf.
DR   InterPro; IPR013546; PII_UdlTrfase/GS_AdlTrfase.
DR   InterPro; IPR010043; UTase/UR.
DR   PANTHER; PTHR47320; BIFUNCTIONAL URIDYLYLTRANSFERASE/URIDYLYL-REMOVING ENZYME; 1.
DR   PANTHER; PTHR47320:SF1; BIFUNCTIONAL URIDYLYLTRANSFERASE_URIDYLYL-REMOVING ENZYME; 1.
DR   Pfam; PF03445; DUF294; 1.
DR   Pfam; PF08335; GlnD_UR_UTase; 1.
DR   Pfam; PF01966; HD; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR   SUPFAM; SSF81593; Nucleotidyltransferase substrate binding subunit/domain; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:OLT46842.1};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   Reference proteome {ECO:0000313|Proteomes:UP000185790};
KW   Transferase {ECO:0000256|ARBA:ARBA00022695}.
FT   DOMAIN          37..132
FT                   /note="Protein-PII uridylyltransferase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03445"
FT   DOMAIN          191..299
FT                   /note="PII-uridylyltransferase/Glutamine-synthetase
FT                   adenylyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF08335"
FT   DOMAIN          451..531
FT                   /note="HD"
FT                   /evidence="ECO:0000259|Pfam:PF01966"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   605 AA;  64520 MW;  AF83B2963F84B802 CRC64;
     MTDHASSPVG SGGGPADRTE VPHPEGVRDL RARTLGLARS MSGRGRSGVA RRAAVVELVT
     TSLESLWKEA TDDVAPDGIA LAAVGSLGRG DMGPVSDLDL VLVHDGRSHS ADEVAQVAQR
     LWYPLWDAGV DLDHAVRSLA QCRQVASKDV PAAVGWLDVR AVAGDAVVVH RASSAVLTDW
     RSASRRRLPE LLSSTRERAE RAGELAYLVE PDLKEARGGI RDAVVLSALA ATWLTDRPHG
     SVDRAYAHLL DVRDTLQVVT GRHSSRLLLA DLDEVADLSG FDDPDELLAS LAEAGREISY
     ALDTTVRRAR QALQRPSVAR RPVLVRGRRA APRLRSVGDG LVEHDGELVL AVDAHPESDP
     LLSLRAAATA ARTGLTLSPV SVASLAQCPP LPEPWPKPAR TAFLSLLASG QAQVAVWEAL
     DLAGVVTRWI PEWAGVRNRP QRAAVHRHTV DRHLVEVVAR AARDRKDVAR ADVLLLSAVL
     HDIGKRAGAA DHSVEGARLA PPILRRMGFD EGVVADVARL VRHHLTLSRL AVTQDPDDPA
     TVAELAAAVD HRVDLLEVLR ALTEADASSL RPGAWTAWRA RLVDDLVGAT ASALRAEGGQ
     EGSAG
//