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Database: UniProt
Entry: A0A1R0FCG6_9RHIZ
LinkDB: A0A1R0FCG6_9RHIZ
Original site: A0A1R0FCG6_9RHIZ 
ID   A0A1R0FCG6_9RHIZ        Unreviewed;       486 AA.
AC   A0A1R0FCG6;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   16-JAN-2019, entry version 13.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=PEB0149_020840 {ECO:0000313|EMBL:OLY44612.1};
OS   Bartonella apis.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bartonellaceae; Bartonella.
OX   NCBI_TaxID=1686310 {ECO:0000313|EMBL:OLY44612.1, ECO:0000313|Proteomes:UP000187344};
RN   [1] {ECO:0000313|EMBL:OLY44612.1, ECO:0000313|Proteomes:UP000187344}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PEB0149 {ECO:0000313|EMBL:OLY44612.1,
RC   ECO:0000313|Proteomes:UP000187344};
RA   Engel P.;
RT   "Comparative genomics of Bartonella apis.";
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OLY44612.1}.
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DR   EMBL; LXYT01000001; OLY44612.1; -; Genomic_DNA.
DR   Proteomes; UP000187344; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000187344};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000187344}.
FT   DOMAIN      176    303       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      391    460       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     184    191       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   486 AA;  55437 MW;  6DAC49F9E0900F5C CRC64;
     MKESLHHLVA QDEGDELFAR VMAQLKVHVG NEAYSSWFGR LQLDEFSRSQ VRLSVPTAFL
     RSWITNHYAT ILTELWRQEC PTLLRVDIVV RGMNRVVKHT VTHKDEDAHV HVQQENTTAS
     SMHNRPERFS GEAQQSVFGS PLDSRYTFDT FVEGPSNRVA LAAARSIAES HKSALRFNPL
     FIHASVGLGK THLLQAIAAA ALQRPTPVRV IYLTAEYFMW RFATAIRDNN ALSFKEQLRD
     IDLLIIDDMQ FLQGKSIQHE FCHLLNMLLD SAKQVVVAAD RAPAELESLD VRVRSRLQGG
     VSLEIESPDF DMRLEMLRKR LKTAQHDDPS ISIPDEVLAH IARIVSGSGR DLEGAFNQLL
     FRQSFEPDLS LNRIDELLDH LTRSGEPKRI RIEEIQRVVA RHYNVSKQDL LSNRRTRTIV
     KPRQVAMYLA KMMTPRSLPE IGRRFGGRDH TTVLHAVRKI EDMVGADQQL AKELELLKRL
     IDEQSA
//
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