ID   A0A1R1A1Y5_9BACL        Unreviewed;       464 AA.
AC   A0A1R1A1Y5;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Sodium:alanine symporter {ECO:0000313|EMBL:OME79550.1};
GN   ORFNames=BK120_21435 {ECO:0000313|EMBL:OME79550.1};
OS   Paenibacillus sp. FSL A5-0031.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=1920420 {ECO:0000313|EMBL:OME79550.1, ECO:0000313|Proteomes:UP000187447};
RN   [1] {ECO:0000313|EMBL:OME79550.1, ECO:0000313|Proteomes:UP000187447}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FSL A5-0031 {ECO:0000313|EMBL:OME79550.1,
RC   ECO:0000313|Proteomes:UP000187447};
RA   Beno S.M.;
RT   "Paenibacillus species isolates.";
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OME79550.1}.
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DR   EMBL; MRTD01000012; OME79550.1; -; Genomic_DNA.
DR   RefSeq; WP_076269530.1; NZ_MRTD01000012.1.
DR   AlphaFoldDB; A0A1R1A1Y5; -.
DR   OrthoDB; 9804874at2; -.
DR   Proteomes; UP000187447; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF5; SODIUM_GLUTAMINE SYMPORTER GLNT-RELATED; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        15..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        67..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        144..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        182..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        209..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        300..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        341..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        379..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        409..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   464 AA;  50181 MW;  2EA7B021063ABE65 CRC64;
     MEQMIQDLIG IVNDFLWSKL LIVMLIAIGL YFTLRSNVLQ LRMLKEMFRL LFESTSGPRG
     SISPFQAFCI SMAARVGTGN ITGIAIAIAL GGPGAVFWMW IIAIIGSASS FVESTLAQVY
     KIKDGESFRG GPAYYMQAGL KKRWMGALFA ILITLSFGLV FNAVQSNTIT IAFENSFGTN
     RLAVGLIMTA IFAVIIIGGV KRIAKLSEYI VVVLAVLYIG VALTIVVINI ADMPAVLALI
     VKNAFGIEQV AGGSLGAALM HGVKRGLFSN EAGMGSAPNA AATATTSHPA KQGLIQALGV
     LFDTLVICTS TAFIILLSGV YEQQGLGGIE LTQAALSVHM GSWASGFLAI MVFLFAFSTL
     MGNYYYGETN IEFLNTSKVW LWLYRICVLA MVIFGSVAKV QLVWDLADLF MGLMVVVNLI
     AITLLSRIAF DVLRNYMKQK KAGRDPKFVK SSIKGLEDVE CWDD
//