ID   A0A1R1CD44_9BACL        Unreviewed;       717 AA.
AC   A0A1R1CD44;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=BK127_03485 {ECO:0000313|EMBL:OMF19967.1};
OS   Paenibacillus sp. FSL H7-0331.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=1920421 {ECO:0000313|EMBL:OMF19967.1, ECO:0000313|Proteomes:UP000187480};
RN   [1] {ECO:0000313|EMBL:OMF19967.1, ECO:0000313|Proteomes:UP000187480}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FSL H7-0331 {ECO:0000313|EMBL:OMF19967.1,
RC   ECO:0000313|Proteomes:UP000187480};
RA   Beno S.M.;
RT   "Paenibacillus species isolates.";
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OMF19967.1}.
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DR   EMBL; MRTH01000002; OMF19967.1; -; Genomic_DNA.
DR   RefSeq; WP_076228611.1; NZ_MRTH01000002.1.
DR   AlphaFoldDB; A0A1R1CD44; -.
DR   STRING; 1920421.BK127_03485; -.
DR   OrthoDB; 9787585at2; -.
DR   Proteomes; UP000187480; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000187480}.
FT   DOMAIN          185..549
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         206..213
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   717 AA;  82061 MW;  33AFA3E39E0BD87E CRC64;
     MEISMQNAYD EEMKRLADTF TEIDRQLQEL ASIPPYTGHD HTEQVLDSIR DSRRRNLAVA
     QSEPYFGRLD FQESGHKEPL PLYIGKVGVE KDLTLELMVV DWRAPVASLF YSYTGGLDAT
     QYDSPDGLVE GLVFLKRNLV IRKQILQRVV DTFDRNGDNM AVTDEFLLYR LGENKDNKLR
     DIVSTIQSEQ DSIIRAVKNS ALLIQGVAGS GKTTVALHRL AYLLYQYRDQ VRAERMIIFA
     PNRMFLDYIS GVLPELGVGD IQQTTFSDWA LELLEHEVKL IDTSEQLRYW FQTGPGRPVM
     NDAAPGRWKG SIKFMQWLEQ ALEQFEASAA PHADYSPWDG VKLSKQTMRQ WYEVEYKHDP
     LMKRRERVMA RVKRWQEMEL EKVWEVHLKK DYKKKASSRL RDYAKHWTAY TPFTFYKELF
     QTAGKPDYLS VELYNEIPKE LLASTEAHLK KKRVQPEDLA ALLFIRSKFQ GIHGDLTFDH
     TVIDEAQDFS PFQVALLNLH TRNQSFTILG DLSQGIHAYQ GIRKWDEFTA LFEEGKTAYF
     QLDRSYRSTM EIIYFANEVL KLGLDQPAAL AIPVFRSGDP VQIVRVDEAK LIASIITAVQ
     KLQTGEISTV AILVRTEARS EVLYKKLNAA GLSVNLIAAG QQHYEGGISI VPTFMAKGLE
     FDAVLIIDVD DVHYPATEQD AKLLYVGCTR ALHSLQIWYD GTASPLVDPI QGEFVIR
//