ID A0A1R1CE85_9BACL Unreviewed; 479 AA.
AC A0A1R1CE85;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=4-hydroxyphenylacetate 3-hydroxylase {ECO:0000313|EMBL:OMF20298.1};
GN ORFNames=BK133_29425 {ECO:0000313|EMBL:OMF20298.1};
OS Paenibacillus sp. FSL H8-0548.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1920422 {ECO:0000313|EMBL:OMF20298.1, ECO:0000313|Proteomes:UP000187405};
RN [1] {ECO:0000313|EMBL:OMF20298.1, ECO:0000313|Proteomes:UP000187405}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FSL H8-0548 {ECO:0000313|EMBL:OMF20298.1,
RC ECO:0000313|Proteomes:UP000187405};
RA Beno S.M.;
RT "Paenibacillus species isolates.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMF20298.1}.
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DR EMBL; MRTK01000081; OMF20298.1; -; Genomic_DNA.
DR RefSeq; WP_076339967.1; NZ_MRTK01000081.1.
DR AlphaFoldDB; A0A1R1CE85; -.
DR STRING; 1920422.BK133_29425; -.
DR OrthoDB; 9785230at2; -.
DR Proteomes; UP000187405; Unassembled WGS sequence.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 1.10.3140.10; 4-hydroxybutyryl-coa dehydratase, domain 1; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR InterPro; IPR004925; HpaB/PvcC/4-BUDH.
DR InterPro; IPR024719; HpaB/PvcC/4-BUDH_C.
DR InterPro; IPR024674; HpaB/PvcC/4-BUDH_N.
DR PANTHER; PTHR36117; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR36117:SF3; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR Pfam; PF03241; HpaB; 1.
DR Pfam; PF11794; HpaB_N; 1.
DR PIRSF; PIRSF000331; HpaA_HpaB; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR000331-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000187405}.
FT DOMAIN 5..268
FT /note="HpaB/PvcC/4-BUDH N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11794"
FT DOMAIN 278..473
FT /note="HpaB/PvcC/4-BUDH C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03241"
FT BINDING 152..155
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
FT BINDING 189
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
FT BINDING 449..452
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
SQ SEQUENCE 479 AA; 54214 MW; CEF7945679AE6B36 CRC64;
MNHRGKRFVE SLEDGRSVWL EGKKVEGLAQ HAAFKGTLRT ISGLFGMLDR PDEQEIIGYR
TTEGHFAHSA FLVPYTAEEL AKRTQAFHVW SKRTNGMMSR LSDYARSIIT GWYGARVQLG
RLDPHFESKI SAYYREARDR DLFLTTAILD PQINRASGLE EERIAERFLH IVRKTEEGIV
VRGAKMIATG APYTHDFVIF SLLKFEQNQE DHAHVLIVPA NSKGLHIVCR ESYADDRPKE
HILSSQYEEM DAVLFFDDVL IPWERVLLQG NVAAVQKLRE YKGANSLAYH QTAVRSIAKF
EFVTGVTMAI AESIGVKDYL HIQEKLGELL SQVDVIKALV IASESEAKLD ESGMLVPEIS
YINTARNIGT KFYPRAIEII QQVGGGGFVQ TPSGMEDFYG PISKFMHLYF EGATVSAEKK
VQLMKLAWDL VGSPLGSRHE LYERFYAGDP IRHYAQQYQA ANKAYFTDPV WKLIHEGGK
//
