GenomeNet

Database: UniProt
Entry: A0A1R1D462_9BACL
LinkDB: A0A1R1D462_9BACL
Original site: A0A1R1D462_9BACL 
ID   A0A1R1D462_9BACL        Unreviewed;       289 AA.
AC   A0A1R1D462;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   11-DEC-2019, entry version 8.
DE   RecName: Full=Prephenate dehydratase {ECO:0000256|RuleBase:RU361254};
DE            Short=PDT {ECO:0000256|RuleBase:RU361254};
DE            EC=4.2.1.51 {ECO:0000256|RuleBase:RU361254};
GN   Name=pheA {ECO:0000256|RuleBase:RU361254};
GN   ORFNames=BK133_15750 {ECO:0000313|EMBL:OMF31684.1};
OS   Paenibacillus sp. FSL H8-0548.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=1920422 {ECO:0000313|EMBL:OMF31684.1, ECO:0000313|Proteomes:UP000187405};
RN   [1] {ECO:0000313|EMBL:OMF31684.1, ECO:0000313|Proteomes:UP000187405}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FSL H8-0548 {ECO:0000313|EMBL:OMF31684.1,
RC   ECO:0000313|Proteomes:UP000187405};
RA   Beno S.M.;
RT   "Paenibacillus species isolates.";
RL   Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O;
CC         Xref=Rhea:RHEA:21648, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:18005, ChEBI:CHEBI:29934; EC=4.2.1.51;
CC         Evidence={ECO:0000256|RuleBase:RU361254};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis;
CC       phenylpyruvate from prephenate: step 1/1.
CC       {ECO:0000256|RuleBase:RU361254}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OMF31684.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; MRTK01000021; OMF31684.1; -; Genomic_DNA.
DR   RefSeq; WP_076337378.1; NZ_MRTK01000021.1.
DR   UniPathway; UPA00121; UER00345.
DR   Proteomes; UP000187405; Unassembled WGS sequence.
DR   GO; GO:0004106; F:chorismate mutase activity; IEA:InterPro.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR008242; Chor_mutase/pphenate_deHydtase.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR018528; Preph_deHydtase_CS.
DR   Pfam; PF01842; ACT; 1.
DR   Pfam; PF00800; PDT; 1.
DR   PIRSF; PIRSF001500; Chor_mut_pdt_Ppr; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Aromatic amino acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Lyase {ECO:0000256|RuleBase:RU361254};
KW   Phenylalanine biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Reference proteome {ECO:0000313|Proteomes:UP000187405}.
FT   DOMAIN          2..190
FT                   /note="Prephenate dehydratase"
FT                   /evidence="ECO:0000259|PROSITE:PS51171"
FT   DOMAIN          205..282
FT                   /note="ACT"
FT                   /evidence="ECO:0000259|PROSITE:PS51671"
FT   SITE            183
FT                   /note="Essential for prephenate dehydratase activity"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001500-2"
SQ   SEQUENCE   289 AA;  31972 MW;  8C5A3CF931AEF20D CRC64;
     MKTIAVLPAG SVSDEAAKHF FRGEEINYKH HRLISDVFLS TVNGISDYSI IPIENTIEGS
     VSLHMDWLVH EVDIPIQAEW VYPSIQNLIG PQSELLDDAG QIDYSRITKV ISHPVAIAQC
     LQFLRTKLPH AVTEHVSSTA EGVRIAKNNP NSGWAAIGTK TAAANEGLDV IASGITDHDN
     NYTRFLLVGS EPYKACQSKQ VKTSILVTLP EDYPGALHQV LAAFAWRKIN LSRIESRPTK
     KKLGNYYFFI DIDMALDSVL LPSAIQEIEA IGCHVRILGS YPSFSEYIK
//
DBGET integrated database retrieval system