ID A0A1R1D9I9_9BACL Unreviewed; 363 AA.
AC A0A1R1D9I9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:OMF35146.1};
GN ORFNames=BK133_10550 {ECO:0000313|EMBL:OMF35146.1};
OS Paenibacillus sp. FSL H8-0548.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1920422 {ECO:0000313|EMBL:OMF35146.1, ECO:0000313|Proteomes:UP000187405};
RN [1] {ECO:0000313|EMBL:OMF35146.1, ECO:0000313|Proteomes:UP000187405}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FSL H8-0548 {ECO:0000313|EMBL:OMF35146.1,
RC ECO:0000313|Proteomes:UP000187405};
RA Beno S.M.;
RT "Paenibacillus species isolates.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMF35146.1}.
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DR EMBL; MRTK01000012; OMF35146.1; -; Genomic_DNA.
DR RefSeq; WP_076336364.1; NZ_MRTK01000012.1.
DR AlphaFoldDB; A0A1R1D9I9; -.
DR STRING; 1920422.BK133_10550; -.
DR OrthoDB; 9802008at2; -.
DR Proteomes; UP000187405; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR CDD; cd04909; ACT_PDH-BS; 1.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000187405}.
FT DOMAIN 2..290
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 363 AA; 39774 MW; 938AD4500201C4E6 CRC64;
MTTVAIFGVG LIGGSLALCF KGKPGIKVIG HSNRPSQVEK YMQRGVVDYA TTSMQEAAEQ
ADFIFICVPV GNLEEYLVKL SGFQLKPGCI VTDAGSTKAS VMERARTLDF GHATFIGGHP
MAGSERTGVE AASSHLYENA FYVLTPEVDT PVEAVDRLIE LLSHTKANIV KVESKEHDEI
AGAISHLPHI IAVSLVNQVR GYNETNELYE SLAAGGFRDI TRIASGDPII WRDILINNRK
VLLELLRDWG KEMEKFVTML EASDGEGIAE AFDAAGQFRS KMPERRKGMI HSAFDCYVDI
PDHPGIIGKI TSELGNSLIN LSNIHISESR EDIPGILRLS FRSQEYLDQA VVLLTAKGYD
VHL
//
