ID A0A1R1F166_9BACL Unreviewed; 383 AA.
AC A0A1R1F166;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN ORFNames=BK138_04000 {ECO:0000313|EMBL:OMF57762.1};
OS Paenibacillus rhizosphaerae.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=297318 {ECO:0000313|EMBL:OMF57762.1, ECO:0000313|Proteomes:UP000187172};
RN [1] {ECO:0000313|EMBL:OMF57762.1, ECO:0000313|Proteomes:UP000187172}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FSL R5-0378 {ECO:0000313|EMBL:OMF57762.1,
RC ECO:0000313|Proteomes:UP000187172};
RA Beno S.M.;
RT "Paenibacillus species isolates.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMF57762.1}.
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DR EMBL; MRTP01000001; OMF57762.1; -; Genomic_DNA.
DR RefSeq; WP_076166138.1; NZ_MRTP01000001.1.
DR AlphaFoldDB; A0A1R1F166; -.
DR STRING; 297318.BK138_04000; -.
DR Proteomes; UP000187172; Unassembled WGS sequence.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW Reference proteome {ECO:0000313|Proteomes:UP000187172}.
FT DOMAIN 27..367
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 383 AA; 43356 MW; 930C5C499975DE42 CRC64;
MKKKIMVIFG TRPEATKMCP VIQQLRHHHE WFETKVVVTG QHREQLSQAL SHFHIQPDVD
LALMKENQSL AYLTSAAIIG LDDIINEDKP DMILVHGDTQ TAMCGSLAAF FHKIPVGHVE
AGLRSHQKYS PWPEEVNRRI VDVITDLLFA PTSVSKNNLN REGYESEHIF ITGQTAVDAA
ILTNKADYKF HNEQLNDLVQ LQGKLITVTA HRRENYGEPM QQMFKAIRRV ADEHPDVHIV
YPVHLSPYVQ DTAFTMLSGH DRIHLLDPIE YPDMINLISR SHLVLSDSGG LQEETPVFNK
PLILMRDTTE RPEAVAANAV YLSGTQEDSI FNIANKLLTD PDLYQQMANA RNPFGDGLAS
KRIVHIIAHH FGLTDDLPNE FEE
//
