ID A0A1R1I1D2_9RHOO Unreviewed; 791 AA.
AC A0A1R1I1D2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=BJN45_14820 {ECO:0000313|EMBL:OMG52555.1};
OS Azonexus hydrophilus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Azonexaceae;
OC Azonexus.
OX NCBI_TaxID=418702 {ECO:0000313|EMBL:OMG52555.1, ECO:0000313|Proteomes:UP000187526};
RN [1] {ECO:0000313|EMBL:OMG52555.1, ECO:0000313|Proteomes:UP000187526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZS02 {ECO:0000313|EMBL:OMG52555.1,
RC ECO:0000313|Proteomes:UP000187526};
RA Salah Z., Rout S.P., Humphreys P.N.;
RT "Alkaliphiles isolated from bioreactors.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMG52555.1}.
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DR EMBL; MTHD01000005; OMG52555.1; -; Genomic_DNA.
DR RefSeq; WP_076096582.1; NZ_MTHD01000005.1.
DR AlphaFoldDB; A0A1R1I1D2; -.
DR STRING; 418702.BJN45_14820; -.
DR OrthoDB; 8552871at2; -.
DR Proteomes; UP000187526; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR PANTHER; PTHR45339:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000187526}.
FT DOMAIN 198..252
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 328..381
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 417..637
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 665..781
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 714
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 791 AA; 87496 MW; F2AE802C96967954 CRC64;
MPVVACSVVE ASFLVALAES VSVIAATGDV GTLLGYPAVA LVQGEVSLPE RIHGDDADIA
EALFGPDIPR GEQVDNLRLR QASGRIRCVK AIYAKRQRDD GVVELTLRLQ DAKSLPRTMD
DAANTANFRA MMENTNDFVY FKDRNHVFTG ASQTLVSLCH PAEQWTDLLG LTDYDVFPEP
YADLYYRLEK QVFSGVAAAQ EIQEFLSKDG QLNGWVDNRK FPIHDEAGEI IGLFGVARDI
TERIHAENRL KESEYFFRDS QRAANIGSYK FDICYDCWTS SEVMEQIFGI GPDYPRTLQG
WLEAVHPDDR QMMQDYFTSN VLKNREPFNK EYRILRRSDG EMRWVLGLGQ LRFDDDGQPC
WMLGTIQDIT ERKQLDAELA HYRHNLETLV EERTLELSKA KDAAEAASFS KSAFLANMSH
EIRTPLNAIT GMAHLIRKGG LSPLQIDQLG KLESAGEHLL EIINAVLELS KIEAGKYLLE
ETGVSVAGVV GGVVSIMQNR ADAKGLKLRT ELCQLPARLL GDPTRLQQTL LNYLSNAIKF
TEHGEVVLQV EMLENGDDNV LLRFSVRDTG IGIAPEAVER LFTAFEQADN TTTRLYGGTG
LGLAIARKLA CMMGGEAGVD STPGIGSTFW FSARLRRCVG DETEMPAATA DDAANAIKRK
FCGARVLLAE DEPINCEITL LLLEDAGLLA DTAEDGMAAV EKAATNDYAL ILMDMQMPRM
DGLEATRHIR RLDRQADTPI LAMTANAFAE DRVRCLEAGM VDFIAKPVKP EIFYSVLLKA
LSAADSRASI L
//
