ID A0A1R1I7V8_9RHOO Unreviewed; 898 AA.
AC A0A1R1I7V8;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=GNAT family N-acetyltransferase {ECO:0000313|EMBL:OMG54795.1};
GN ORFNames=BJN45_06335 {ECO:0000313|EMBL:OMG54795.1};
OS Azonexus hydrophilus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Azonexaceae;
OC Azonexus.
OX NCBI_TaxID=418702 {ECO:0000313|EMBL:OMG54795.1, ECO:0000313|Proteomes:UP000187526};
RN [1] {ECO:0000313|EMBL:OMG54795.1, ECO:0000313|Proteomes:UP000187526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZS02 {ECO:0000313|EMBL:OMG54795.1,
RC ECO:0000313|Proteomes:UP000187526};
RA Salah Z., Rout S.P., Humphreys P.N.;
RT "Alkaliphiles isolated from bioreactors.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMG54795.1}.
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DR EMBL; MTHD01000002; OMG54795.1; -; Genomic_DNA.
DR RefSeq; WP_076093188.1; NZ_MTHD01000002.1.
DR AlphaFoldDB; A0A1R1I7V8; -.
DR STRING; 418702.BJN45_06335; -.
DR OrthoDB; 9807426at2; -.
DR Proteomes; UP000187526; Unassembled WGS sequence.
DR GO; GO:0043758; F:acetate-CoA ligase (ADP-forming) activity; IEA:InterPro.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd04301; NAT_SF; 1.
DR Gene3D; 3.40.630.30; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR003781; CoA-bd.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR043938; Ligase_CoA_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032875; Succ_CoA_lig_flav_dom.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR43334; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR PANTHER; PTHR43334:SF1; ACETATE--COA LIGASE [ADP-FORMING]; 1.
DR Pfam; PF13302; Acetyltransf_3; 1.
DR Pfam; PF13549; ATP-grasp_5; 1.
DR Pfam; PF13380; CoA_binding_2; 1.
DR Pfam; PF19045; Ligase_CoA_2; 1.
DR Pfam; PF13607; Succ_CoA_lig; 1.
DR SMART; SM00881; CoA_binding; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS51186; GNAT; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00409};
KW Reference proteome {ECO:0000313|Proteomes:UP000187526};
KW Transferase {ECO:0000313|EMBL:OMG54795.1}.
FT DOMAIN 497..533
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT DOMAIN 739..897
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
SQ SEQUENCE 898 AA; 98487 MW; 4C0DAE773E66FFA1 CRC64;
MLEQHYLTAL FEPKSVAVIG ASDRENSVGN IIFKNILGSG YKGRLYAINP KHETIQGQPA
YKSIEEIGAR VEMAVIATRP QTVPQIIEQC GRSGVRNVIV IASGFSEAGH IGAALERKVM
EIARSYNVRV LGPNCLGIIR PELGLNATFT KITADPGNLA LVSQSGAMCS AVLDWAKANQ
VGFSSVISLG MTADVDFGEI LDYLIYDSRT HYILMYVEGI RNARRFMSAL RSAARIKPII
LLKAGRHEAG SQAATAHSGM AAISDTVFDA AVRRAGVVRV KNVGQLFYAA KALASKFRPQ
GDRLAIITNG GGPGAMAADR AGDLGIPLAQ LSTETMGNLN KVLPTNWSHS NPVDIGGDAT
PERYRDALLS ISQDPNVDST LVMLSPQAMT DPLGVAQAII SISDKLNRRI ICCWMGEAQV
AEARKLLEDS GIPAFRMPET AIELFHHISK YYRNQKLLLQ TPEPTRQHGR PETEGAKMLI
EALLAERRKV LSEMESKAIL RAFKVPVAQT MVARTATEAL LLAEQIGFPV AMKVDSPELP
HKSDAGGVRL NIQNAPAVRN AYHDIIDTVQ KRHPTAKING VSIEPFLSRP HGREIMIGVI
RDPIFGPVIT FGAGGFDNEI FSDRSVALPP LNKFLAKDLI ESTRTSKILD QFHNMPPVDR
EAIKEVLLCI SEMVCELPWI IELDINPLIV DEHGAIAADA RIVIDHAANS SGDRYAHMAI
YPYPVHLIQD WTMNDGKVVT IRPIRPEDAD MEQEFVKAMS DESRYYRFMD TLRELTQTML
VRFTQIDYDR EMALVATLPD PESGKESQIG VARYVLNPDG ESVEFALAVG DDWQKCGVGR
KLMTALIDCA RMKGYRAVVG DVLSTNSKMF RLMTSLGFTI HPHPDDTAVK RVVKPLTG
//
