ID A0A1R1IEB2_9RHOO Unreviewed; 465 AA.
AC A0A1R1IEB2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=BJN45_01820 {ECO:0000313|EMBL:OMG56899.1};
OS Azonexus hydrophilus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Azonexaceae;
OC Azonexus.
OX NCBI_TaxID=418702 {ECO:0000313|EMBL:OMG56899.1, ECO:0000313|Proteomes:UP000187526};
RN [1] {ECO:0000313|EMBL:OMG56899.1, ECO:0000313|Proteomes:UP000187526}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ZS02 {ECO:0000313|EMBL:OMG56899.1,
RC ECO:0000313|Proteomes:UP000187526};
RA Salah Z., Rout S.P., Humphreys P.N.;
RT "Alkaliphiles isolated from bioreactors.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMG56899.1}.
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DR EMBL; MTHD01000001; OMG56899.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R1IEB2; -.
DR STRING; 418702.BJN45_01820; -.
DR Proteomes; UP000187526; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43065:SF50; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF08448; PAS_4; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000187526}.
FT DOMAIN 23..95
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 114..166
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 225..461
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 179..216
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 465 AA; 52363 MW; 3E347158341D0D30 CRC64;
MKESNRKLLE SEHKRASDSR RNLQLFLSQI IDGDPVPTLV IDASHRITHW NKACAAISGL
PAEQMVGTWD QWKAFYPESR PIMADLIVDG SLEERFDNYY HNLFRRSKTI ADAFEAESFF
PHLGSSGRWL FFTTAPIRDS DGKIIGAIET LQDVTERRLA EEQLLQYQGQ LEAQVESRTQ
ALARANQQLA KEHEELTNLL RKIEEAQQQL LQSEKMAAIG QLAAGVAHEI NNPIGFVNSN
LGSLKTYTTN LLHLIDAYES GQAAAIAEAK RQADLEFLRE DLPSLLAESQ EGLDRVTRIV
QDLKDFSRVD QAERQRADLN AALHSTLNVV RNELKYKADV IIELGEIPEI DCVPAQLNQV
FMNLLVNAAQ AIPERGKIFV RSGLERDHVW FEIEDTGSGM SEETRHRIFE PFFTTKPVGK
GTGLGLSISY DIIVKKHHGR VDVRSEPGKG TCFRIWLPID APAND
//
