ID A0A1R1M8T0_9GAMM Unreviewed; 417 AA.
AC A0A1R1M8T0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Heme d1 biosynthesis radical SAM protein NirJ {ECO:0000313|EMBL:OMH36251.1};
GN ORFNames=BGP75_09885 {ECO:0000313|EMBL:OMH36251.1};
OS Motiliproteus sp. MSK22-1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Motiliproteus.
OX NCBI_TaxID=1897630 {ECO:0000313|EMBL:OMH36251.1, ECO:0000313|Proteomes:UP000187359};
RN [1] {ECO:0000313|EMBL:OMH36251.1, ECO:0000313|Proteomes:UP000187359}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MSK22-1 {ECO:0000313|EMBL:OMH36251.1,
RC ECO:0000313|Proteomes:UP000187359};
RA Nakajima Y., Yoshizawa S., Ogura Y., Hayashi T., Kogure K.;
RT "Draft genome of Motiliproteus sp. strain MSK22-1.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMH36251.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MIEQ01000035; OMH36251.1; -; Genomic_DNA.
DR RefSeq; WP_076718132.1; NZ_MIEQ01000035.1.
DR AlphaFoldDB; A0A1R1M8T0; -.
DR STRING; 1897630.BGP75_09885; -.
DR OrthoDB; 9792276at2; -.
DR Proteomes; UP000187359; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21123; SPASM_MftC-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR023992; HemeD1_Synth_NirJ.
DR InterPro; IPR017200; PqqE-like.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR NCBIfam; TIGR04051; rSAM_NirJ; 1.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR PIRSF; PIRSF037420; PQQ_syn_pqqE; 1.
DR SFLD; SFLDF00393; heme_D1_biosynthesis_(NirJ-lik; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000187359};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 22..233
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 417 AA; 46790 MW; 832BF9BC0A1FD538 CRC64;
MFRLTHYVRE LVSPGSQRKP GTPPGPVVIW NLIRRCNLLC KHCYSISADT DFKGELNTDE
AFAVLEDLKG FKVPALILSG GEPLLRPDIY QIGERAKELG LYTGLSTNGT LIDEQEIKKL
KQVGFDYVGI SLDGLEKTHD EFRRKEGAFA ASFKAVELCK EAGIKVGLRF TLTEDNASEL
AELLDISKEY DIEKFYLSHL NYAGRGNKNR GDDAFHRTTR DALDLLLKEA LDDVKEGRAR
EFVTGNNDAD GVYLYKWALQ NFPEQAEHIR EYLEAWGGNA SGLHIANIDN LGTVHPDTFW
WNYDLGNVRQ KPFSQIWSES DDPLMQGFRQ QPRPVTGRCG ACQYLKICGG NTRVRAYQLT
DDPWAEDPAC YLTDQEIGID TDVERLQTTP YVHKSKSQNG SVAKGTGLAE SIAVQNI
//
