ID A0A1R1PIR3_ZANCU Unreviewed; 1037 AA.
AC A0A1R1PIR3;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Gypsy retrotransposon integrase-like protein 1 {ECO:0000256|ARBA:ARBA00039658};
GN ORFNames=AX774_g5684 {ECO:0000313|EMBL:OMH80871.1};
OS Zancudomyces culisetae (Gut fungus) (Smittium culisetae).
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota; Kickxellomycotina;
OC Harpellomycetes; Harpellales; Legeriomycetaceae; Zancudomyces.
OX NCBI_TaxID=1213189 {ECO:0000313|EMBL:OMH80871.1, ECO:0000313|Proteomes:UP000188320};
RN [1] {ECO:0000313|Proteomes:UP000188320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=COL-18-3 {ECO:0000313|Proteomes:UP000188320};
RA Wang Y., White M., Kvist S., Moncalvo J.-M.;
RL Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMH80871.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LSSK01001054; OMH80871.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R1PIR3; -.
DR Proteomes; UP000188320; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd00303; retropepsin_like; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR47266; ENDONUCLEASE-RELATED; 1.
DR PANTHER; PTHR47266:SF19; RIBONUCLEASE H; 1.
DR Pfam; PF13650; Asp_protease_2; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF00098; zf-CCHC; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Reference proteome {ECO:0000313|Proteomes:UP000188320};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 241..257
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
FT DOMAIN 845..941
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 293..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 83..117
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1037 AA; 119720 MW; 527B6DB82F0870FC CRC64;
MKVPETFDCT SGMDPKEWVG KYRIIAKLNK WDEVDWIDFV QLHLGKRELV WYKRNTLKFT
SWEEFTKQFI TKFGPKDQSL KYLEQLKTIS QEEFETIEEL EYELEELLTK SKITEEKQKL
NWLLSALTTE NRIRVRDAGV ESWTEIVELI SKDEQQLAIQ RKPSTIDKEN SKKQTKPRIQ
LQHSGRPIKD MAQEKLGYGE MVKKMEEWSL NLLTKVDELM ENKLREHRRP RQQSYARGPI
KCFKCGVEGH KVPDCPEQSK AQDTSVNFIE LSTDKEEDAD VFAVQRGIHP RGVQKPYDFS
NKRVTPNTTN ARVPQRKVEE MRTEMEIEQP AKPQAVVTAK ELVAREDTPK SRNKLIPKIT
EGIEPFSLVE DLKSYYPHIS LPQLIQAAPQ LTHDMSQLAK KVKKEEINEI RLNPSKTSNC
KIEITIFGRR MWAIVDTGAA CSVATPNLVY GWGLITEQSD GQVIVTADGR RHAPRGIIRD
VPVQIGKYIF ATDITIMERT DDILILGTDW LLAHKTKLDM QKGELALPVG KQLLLAPLYT
RVTAEGADSD EAEVYLVISE RQGESTQEVI MDPRVTELME ENKELFIEDV EQLTQTDVTQ
HRIELTHETP IRQRPYRIPF HLYEKDITGR VARWAMILRN YNYSIVHCMG KRNPADALSR
LPANQPSTSH EELDILTLDF LYYTAITTYL REKEYPRGAD EKFREKLRNK ARKYTLKNDR
LCRVIKGQVK EVLHEKNIEE TIQSIHAEGH HGIENTWLKV KEEYTGEGLY EVVKKIVNEC
ITCQRYKGGR TRRSNLNPIF SPRPFSIFGI DAIGPINPVS KTGNRFILTG IDYFTKWPVA
AAWFGVPSQI ITDRGSGFVS DLAEQVYKEL GIRHTPTTPY RPQSNGQVER LNQTLKNALV
RQCRKDKQNW DKFIWKSLLA IRTMRNKSTK YSPAELLYGV QIATPSVWTP PPDVDDLDIA
VQERIDAIKS SLPEMRTDSV RNNVLAKERD RESYNKQVKS YKFNIGDLVL KMTEQTQSKL
EEIWEGLSRL TLGTIVA
//
