ID A0A1R1S4L9_9ACTN Unreviewed; 372 AA.
AC A0A1R1S4L9;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Regulatory protein {ECO:0000313|EMBL:OMI33119.1};
GN ORFNames=SPAR_43091 {ECO:0000313|EMBL:OMI33119.1};
OS Streptomyces sparsogenes DSM 40356.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1331668 {ECO:0000313|EMBL:OMI33119.1, ECO:0000313|Proteomes:UP000186168};
RN [1] {ECO:0000313|EMBL:OMI33119.1, ECO:0000313|Proteomes:UP000186168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40356 {ECO:0000313|EMBL:OMI33119.1,
RC ECO:0000313|Proteomes:UP000186168};
RA Coyne S., Seebeck F.P.;
RT "Genome sequence of Streptomyces sparsogenes DSM 40356.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMI33119.1}.
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DR EMBL; ASQP01000562; OMI33119.1; -; Genomic_DNA.
DR RefSeq; WP_065961232.1; NZ_ASQP01000562.1.
DR AlphaFoldDB; A0A1R1S4L9; -.
DR STRING; 67365.GCA_001704635_05741; -.
DR Proteomes; UP000186168; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd01107; HTH_BmrR; 1.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 1.10.1660.10; -; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR000551; MerR-type_HTH_dom.
DR InterPro; IPR047057; MerR_fam.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR30204:SF96; MERR FAMILY REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR Pfam; PF13411; MerR_1; 1.
DR Pfam; PF13672; PP2C_2; 1.
DR SMART; SM00422; HTH_MERR; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR PROSITE; PS00552; HTH_MERR_1; 1.
DR PROSITE; PS50937; HTH_MERR_2; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000186168}.
FT DOMAIN 3..73
FT /note="HTH merR-type"
FT /evidence="ECO:0000259|PROSITE:PS50937"
FT DOMAIN 131..367
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
SQ SEQUENCE 372 AA; 39598 MW; D4700F8F54E88177 CRC64;
MSLLTIGAFA KASRLSPKAL RLYDELGLLA PARVDPVTGY RLYAPGQLER ARLVAWLRRL
GMPLARIREV CDLGERDAAA AAREVRAFWA RVEAETAARR DLAAFLIDHL TWKDPLMSPT
VEQAAEPLEI RYAALSDTGL VRESNQDTAY AGPRLLAVAD GFGAAGAPAG AAAVRELRRV
DAEGVGTGVV PAGELLNALE EAVEQAGRAV RDIAGSGPAP HEVGTTLTAM LWTGSRLALV
HIGDSRAYLL RDGELFQITH DHTVVQSMVD EGRLSPEEAT SHPQRSLLLR ALTGGRDAAT
ADIRLHDARP GDRYLLCSDG LSAVVPTEDV RRVVGSAPDP EGAVRELVAL ANRAGGPDNV
SCVVADVVRP VD
//
