ID A0A1R1S6P2_9ACTN Unreviewed; 377 AA.
AC A0A1R1S6P2;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Protein-L-isoaspartate O-methyltransferase {ECO:0000256|ARBA:ARBA00013346};
DE EC=2.1.1.77 {ECO:0000256|ARBA:ARBA00011890};
DE AltName: Full=L-isoaspartyl protein carboxyl methyltransferase {ECO:0000256|ARBA:ARBA00031350};
DE AltName: Full=Protein L-isoaspartyl methyltransferase {ECO:0000256|ARBA:ARBA00030757};
DE AltName: Full=Protein-beta-aspartate methyltransferase {ECO:0000256|ARBA:ARBA00031323};
GN ORFNames=SPAR_39064 {ECO:0000313|EMBL:OMI33947.1};
OS Streptomyces sparsogenes DSM 40356.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1331668 {ECO:0000313|EMBL:OMI33947.1, ECO:0000313|Proteomes:UP000186168};
RN [1] {ECO:0000313|EMBL:OMI33947.1, ECO:0000313|Proteomes:UP000186168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40356 {ECO:0000313|EMBL:OMI33947.1,
RC ECO:0000313|Proteomes:UP000186168};
RA Coyne S., Seebeck F.P.;
RT "Genome sequence of Streptomyces sparsogenes DSM 40356.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005369}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMI33947.1}.
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DR EMBL; ASQP01000501; OMI33947.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R1S6P2; -.
DR STRING; 67365.GCA_001704635_04936; -.
DR Proteomes; UP000186168; Unassembled WGS sequence.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR11579; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11579:SF0; PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE; 1.
DR Pfam; PF01135; PCMT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:OMI33947.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186168};
KW Transferase {ECO:0000313|EMBL:OMI33947.1}.
SQ SEQUENCE 377 AA; 41136 MW; 492768675313FE7A CRC64;
MSAGVLSPDW ASAFHAVPRS AFLPDLMWPF DMSTGRSTAV NKADDPAGWL RYADSDAPIV
TQWDDGKHSG TEPGQVSTSS ASMPSVVFSM LRDLDVRVGH RVLEIGTGTG WNAALLAHRL
GAENVVTVEV DAAVAAAARA SLDRFGTPVR VVHGDGLQGC PDAAPYDRII ATCGLRSIPF
SWVRQCRSHG IIVAPWGTHY DNGDAVARLI VAADGRSASG TFTGPVEFMK LRAQRLPPMV
HTDYVPGSVA DGDESSTTIT EAQFVAGRFS PQRFALSLLV RDCRHVVAEK EDGARPVWFY
GLTDRSWACV QFRDGAPARV WQSGPRRLWD EAEAAYRWWE EEGRPGFDRF GLTVDRHGER
IWLDAPDNPV PARAGWP
//
