ID A0A1R1S7E7_9ACTN Unreviewed; 351 AA.
AC A0A1R1S7E7;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:OMI34217.1};
GN ORFNames=SPAR_37538 {ECO:0000313|EMBL:OMI34217.1};
OS Streptomyces sparsogenes DSM 40356.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1331668 {ECO:0000313|EMBL:OMI34217.1, ECO:0000313|Proteomes:UP000186168};
RN [1] {ECO:0000313|EMBL:OMI34217.1, ECO:0000313|Proteomes:UP000186168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 40356 {ECO:0000313|EMBL:OMI34217.1,
RC ECO:0000313|Proteomes:UP000186168};
RA Coyne S., Seebeck F.P.;
RT "Genome sequence of Streptomyces sparsogenes DSM 40356.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OMI34217.1}.
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DR EMBL; ASQP01000477; OMI34217.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1R1S7E7; -.
DR STRING; 67365.GCA_001704635_01529; -.
DR Proteomes; UP000186168; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd01574; PBP1_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000186168};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 14..68
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 351 AA; 37420 MW; FD471AA31F350C69 CRC64;
MRAGARADRR VQRASMADVA RLAGVSSQTV SRVSNGYSGV TEETRRQVLA AMKELGYRPN
SAARALKRGE FRTIGVITFS LATTGNVRTL EAIATSAAQE GYAVTLLPVA VPTQDEVRGA
FSRLGELAVD AVIVIMEVHL LDAATVSLPP GVQVVVADSD AGDRYSVVDT DQAGGTRAAV
RHLLDLGHRT VWHLAGPEES FAAQRRADAW RATLTDADRT PPPLVRGDWS AESGYRAGLR
LAEEADCTAV FAANDQMALG LLRALHERGR KVPEDVSVIG FDDIPEAGSF LPPLTTVHQD
FAEVGRRCVE GVLRQMREDV TEPGTTLVPT RLVLRGSTAP PPARLRAGGA G
//
